Exam 10: Chromosome Exam Title Tbd

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A diploid organism with a genome size of n = 23 experienced a Robertsonian translocation. How many chromosomes would you expect to see in the karyotype of a somatic cell in an affected individual?

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C

Chromosomal translocation involves chromosome breakage and reattachment of the broken segment to a ________chromosome.

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_________is rare and occurs most commonly when repetitive regions of homologous chromosomes misalign, resulting in partial deletions and partial duplications.

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Unequal crossover

Which of the following is FALSE of Down syndrome?

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During gametogenesis, what percentage of gametes would be aneuploid if the nondisjunction event occurs during meiosis I?

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What is meant by the "beads on a string" model of chromatin?

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A cell can form 10 nm chromatin fibers, but not 30 nm fibers. Which molecule has likely been removed or mutated in this cell?

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What structure, seen during synapsis, is indicative of a chromosome inversion?

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A chromosome contains the following gene order: A B C D • E F G H Which of the following rearrangements represents a paracentric inversion?

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Given a chromosome with the gene order, A B C D • E F G H, and an inverted chromosome with this gene order, A F E • D C B G H, which of the following recombinant chromosomes would result from a crossover between C and D? A) ABCCBGH and \cdotC B) ABCD E FA and \cdot\cdot C) ABCDEFA and \cdot\cdot D) ABCD E FA and \cdot E) A BCCBGH and \cdot\cdot

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Prader- Willi and Angelman syndromes are caused by which type of chromosomal mutations, both in connection with chromosome 15?

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Which of the following is FALSE regarding organization in an interphase nucleus?

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Nucleosomes are comprised of how many molecules of histones?

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Which of the following did Hermann Muller determine when studying eye color variegation in Drosophila melanogaster?

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In an allopolyploid organism, what is true regarding the fertility of interspecies hybrids?

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The figure shows the structure of a series of fruit fly deletion mutants. The gap in each line represents the segment of the chromosome that is deleted in each mutant. Stains that were heterozygous for each deletion mutation and a point mutation (A, B, C, D, E, and F) were created and analyzed for wild- type (+) or mutant (- ) phenotypes. The results of the analyses are shown in the table.  The figure shows the structure of a series of fruit fly deletion mutants. The gap in each line represents the segment of the chromosome that is deleted in each mutant. Stains that were heterozygous for each deletion mutation and a point mutation (A, B, C, D, E, and F) were created and analyzed for wild- type (+) or mutant (- ) phenotypes. The results of the analyses are shown in the table.     \begin{array}{|c|c|c|c|c|c|c|} \hline \text { Deletion } & \mathrm{A} & \mathrm{B} & \mathrm{C} & \mathrm{D} & \mathrm{E} & \mathrm{F} \\ \hline \text { Deletion 1 } & + & - & + & - & + & - \\ \hline \text { Deletion 2 } & + & + & - & + & - & + \\ \hline \text { Deletion 3 } & - & + & - & + & - & - \\ \hline \text { Deletion 4 } & - & + & + & + & + & + \\ \hline \text { Deletion 5 } & - & - & + & + & - & - \\ \hline \end{array}    Which of the following is the correct order of the six point mutations on the chromosome? Deletion Deletion 1 + - + - + - Deletion 2 + + - + - + Deletion 3 - + - + - - Deletion 4 - + + + + + Deletion 5 - - + + - - Which of the following is the correct order of the six point mutations on the chromosome?

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During gametogenesis, what percentage of gametes would be trisomic if the nondisjunction event occurs during meiosis II?

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In balanced translocation heterozygotes, viable gametes and progeny are produced by which pattern(s) of chromosome segregation?

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Active transcription occurs where with respect to matrix attachment regions (MARs)?

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Karyotypes are a method for displaying chromosomes by grouping them into homologous pairs based on what two distinguishing factors?

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