Question 1

In a cell with a diploid number of 12, how many chromatids are present at prophase of mitosis?

Accepted Answer

A) 24 
B) 48 
C) 6 
D) 12 
E) none of the above 
A) 24 
B) 48 
C) 6 
D) 12 
E) none of the above A

Question 2

The phase of the cell cycle associated with the doubling of the amount of DNA in the cell is

Accepted Answer

A) G1. 
B) G0. 
C) G2. 
D) S. 
E) M. 
A) G1. 
B) G0. 
C) G2. 
D) S. 
E) M. D

Question 3

A particular strain of yeast produces strains with a mutant cdc2 gene, resulting in little to no production of the Cdc2 protein kinase. As a result, one would expect that these cells would

Accepted Answer

A) lack chromosome condensation. 
B) not have the nuclear envelope disperse. 
C) not enter M phase. 
D) all of the above 
E) none of the above 
A) lack chromosome condensation. 
B) not have the nuclear envelope disperse. 
C) not enter M phase. 
D) all of the above 
E) none of the above D

Question 4

The multiple sites of DNA replication along eukaryotic chromosomes are known as

Accepted Answer

A) ARS elements. 
B) helicase loaders. 
C) replicons. 
D) multi- replication forks. 
E) none of the above 
A) ARS elements. 
B) helicase loaders. 
C) replicons. 
D) multi- replication forks. 
E) none of the above

Question 5

Which of the following families of proteins is associated with the contractile ring?

Accepted Answer

A) delta 
B) alpha 
C) rho 
D) sigma 
E) kappa 
A) delta 
B) alpha 
C) rho 
D) sigma 
E) kappa

Question 6

Which enzyme is involved in proofreading during DNA replication?

Accepted Answer

A) 3' to 5' endonuclease 
B) 5' to 3' endonuclease 
C) 5' to 3' exonuclease 
D) DNA polymerase 
E) 3' to 5' exonuclease 
A) 3' to 5' endonuclease 
B) 5' to 3' endonuclease 
C) 5' to 3' exonuclease 
D) DNA polymerase 
E) 3' to 5' exonuclease

Question 7

DNA replication

Accepted Answer

A) requires a type of RNA polymerase. 
B) proceeds by making two continuous strands. 
C) is partially regulated by promoter/terminator sites. 
D) is conservative. 
E) is not edited once polymerization has occurred. 
A) requires a type of RNA polymerase. 
B) proceeds by making two continuous strands. 
C) is partially regulated by promoter/terminator sites. 
D) is conservative. 
E) is not edited once polymerization has occurred.

Question 8

Ras is to Raf, as MEK is to

Accepted Answer

A) MAPK. 
B) Ras. 
C) cell growth. 
D) tyrosine. 
E) Cdc. 
A) MAPK. 
B) Ras. 
C) cell growth. 
D) tyrosine. 
E) Cdc.

Question 9

The longest phase of the cell cycle is

Accepted Answer

A) interphase. 
B) metaphase. 
C) prophase. 
D) anaphase. 
E) telophase. 
A) interphase. 
B) metaphase. 
C) prophase. 
D) anaphase. 
E) telophase.

Question 10

A NASA probe returned samples of rocks from the surface of Mars. From these rocks, a prokaryotic organism was isolated and remained viable under conditions similar to that of Mars. The organisms are capable of dividing to replicate themselves. An experiment was performed to determine whether the DNA replication of these organisms was semi- conservative using N15/N14 , similar to that of Mendelson and Stahl. If the method of DNA replication were conservative, after one generation one would expect to see

Accepted Answer

A) all of the DNA in the light (N14)band. 
B) all of the DNA in the heavy (N15)band. 
C) half of the DNA in the light band, the other half in the heavy band. 
D) all of the DNA at a point midway between the heavy and light bands. 
E) none of the above 
A) all of the DNA in the light (N14)band. 
B) all of the DNA in the heavy (N15)band. 
C) half of the DNA in the light band, the other half in the heavy band. 
D) all of the DNA at a point midway between the heavy and light bands. 
E) none of the above

Question 11

DNA repair in eukaryotes that facilitates replication in regions of thymine dimers is mediated by a unique DNA polymerase

Accepted Answer

A) 6. 
B) a. 
C) a 
D) fi. 
E) y 
A) 6. 
B) a. 
C) a 
D) fi. 
E) y

Question 12

What is the ploidy of an organism that is 7n, where n = 5?

Accepted Answer

A) 12 
B) 57 
C) 7 
D) 35 
E) 5 
A) 12 
B) 57 
C) 7 
D) 35 
E) 5

Question 13

A population of T cells has been stimulated to proliferate in response to a particular antigen. A sample of 1000 cells is examined microscopically in revealing that 200 of these cells are in the various stages of mitosis. Of the remaining 800 in interphase, 400 have x amount of DNA, 250 have 2x, and the remaining 150 have amounts somewhere between x and 2x. Additional analysis reveals that the G2 phase of the cell cycle lasts 2 hours. What is the total length of the cell cycle?

Accepted Answer

A) 6.4 hours 
B) 4 hours 
C) 13.3 hours 
D) 2.5 hours 
E) 8 hours 
A) 6.4 hours 
B) 4 hours 
C) 13.3 hours 
D) 2.5 hours 
E) 8 hours

Question 14

The phase of the cell cycle that varies most in duration in various cell types is

Accepted Answer

A) M. 
B) S. 
C) G1. 
D) G2. 
E) both A and B 
A) M. 
B) S. 
C) G1. 
D) G2. 
E) both A and B

Question 15

Using polyethylene glycol (PEG), early G1 phase cells were fused with S phase cells. Of the following events, which would you expect to be induced in the G1 cells as a result of the fusion?

Accepted Answer

A) spindle fiber formation 
B) mitosis 
C) condensation of chromosomes 
D) cytokinesis 
E) DNA replication 
A) spindle fiber formation 
B) mitosis 
C) condensation of chromosomes 
D) cytokinesis 
E) DNA replication

Question 16

The protein(s)that facilitate the unfolding of chromatin fibers ahead of the replication fork is (are)

Accepted Answer

A) helicase. 
B) replisomal proteins. 
C) scaffold proteins. 
D) chromatin remodeling proteins. 
E) both A and B 
A) helicase. 
B) replisomal proteins. 
C) scaffold proteins. 
D) chromatin remodeling proteins. 
E) both A and B

Question 17

During the G2 checkpoint in eukaryotic cells, the cell is assessed with regard to

Accepted Answer

A) chromosome attachment to the spindle. 
B) DNA damage. 
C) DNA replication. 
D) presence of growth factors. 
E) nutrients. 
A) chromosome attachment to the spindle. 
B) DNA damage. 
C) DNA replication. 
D) presence of growth factors. 
E) nutrients.

Question 18

DNA replication is

Accepted Answer

A) dispersive. 
B) semi- conservative. 
C) irregular. 
D) conservative. 
E) none of the above 
A) dispersive. 
B) semi- conservative. 
C) irregular. 
D) conservative. 
E) none of the above

Question 19

UV (ultraviolet)light- treated bacteria would most likely have DNA damage in the form of

Accepted Answer

A) pyrimidine dimer formation. 
B) deamination. 
C) intercalation of the bases. 
D) analog incorporation. 
E) direct transition of the bases. 
A) pyrimidine dimer formation. 
B) deamination. 
C) intercalation of the bases. 
D) analog incorporation. 
E) direct transition of the bases.

Question 20

Cyclins modulate the progression of cells through the cell cycle by

Accepted Answer

A) directly activating G proteins. 
B) increasing the production of DNA polymerases. 
C) inducing synthesis of constitutively active forms of growth cell receptors. 
D) activating protein kinases that are critical regulators of cell division. 
E) degrading histones. 
A) directly activating G proteins. 
B) increasing the production of DNA polymerases. 
C) inducing synthesis of constitutively active forms of growth cell receptors. 
D) activating protein kinases that are critical regulators of cell division. 
E) degrading histones.

Exam 19: The Cell Cycle, Dna Replication, and Mitosis

In a cell with a diploid number of 12, how many chromatids are present at prophase of mitosis?

The phase of the cell cycle associated with the doubling of the amount of DNA in the cell is

A particular strain of yeast produces strains with a mutant cdc2 gene, resulting in little to no production of the Cdc2 protein kinase. As a result, one would expect that these cells would

The multiple sites of DNA replication along eukaryotic chromosomes are known as

Which of the following families of proteins is associated with the contractile ring?

Which enzyme is involved in proofreading during DNA replication?

DNA replication

Ras is to Raf, as MEK is to

The longest phase of the cell cycle is

DNA repair in eukaryotes that facilitates replication in regions of thymine dimers is mediated by a unique DNA polymerase

What is the ploidy of an organism that is 7n, where n = 5?

The phase of the cell cycle that varies most in duration in various cell types is

Using polyethylene glycol (PEG), early G1 phase cells were fused with S phase cells. Of the following events, which would you expect to be induced in the G1 cells as a result of the fusion?

The protein(s)that facilitate the unfolding of chromatin fibers ahead of the replication fork is (are)

During the G2 checkpoint in eukaryotic cells, the cell is assessed with regard to

DNA replication is

UV (ultraviolet)light- treated bacteria would most likely have DNA damage in the form of

Cyclins modulate the progression of cells through the cell cycle by

A Preview of the Cell

The Chemistry of the Cell

The Macromolecules of the Cell

Cells and Organelles

Bioenergetics: The Flow of Energy in the Cell

Enzymes: The Catalysts of Life

Membranes: Their Structure, Function, and Chemistry

Transport Across Membranes: Overcoming the Permeability Barrier

Chemotrophic Energy Metabolism: Glycolysis and Fermentation

Chemotrophic Energy Metabolism: Aerobic Respiration

Phototrophic Energy Metabolism: Photosynthesis

The Endomembrane System and Peroxisomes

Signal Transduction Mechanisms: I Electrical and Synaptic Signaling in Neurons

Signal Transduction Mechanisms: Ii Messengers and Receptors

Cytoskeletal Systems

Cellular Movement: Motility and Contractility

Beyond the Cell: Cell Adhesion, Cell Junctions, and Extracellular Structures

The Structural Basis of Cellular Information: DNA, Chromosomes, and the Nucleus

Sexual Reproduction, Meiosis, and Genetic Recombination

Gene Expression: I the Genetic Code and Transcription

Gene Expression: II Protein Synthesis and Sorting

The Regulation of Gene Expression

Cancer Cells

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