Question 1

Which of the following is associated with extracellular digestion via release of the contents of lysosomes directly to the environment?

Accepted Answer

A) rheumatoid arthritis 
B) fertilization of animal eggs 
C) autophagy 
D) only A and B 
E) choices A, B, and C 
A) rheumatoid arthritis 
B) fertilization of animal eggs 
C) autophagy 
D) only A and B 
E) choices A, B, and C D

Question 2

A protein is destined to be secreted from a cell. In which of the following organelles would you expect to find the protein first?

Accepted Answer

A) lysosome 
B) endosome 
C) Golgi apparatus 
D) secretory vesicle 
A) lysosome 
B) endosome 
C) Golgi apparatus 
D) secretory vesicle C

Question 3

act as proton pumps and keep the internal proton concentration of lysosomes high.

Accepted Answer

ATPases

Question 4

Which of the following cellular processes has/have been linked to cancer/tumor formation?

Accepted Answer

A) autophagy 
B) EGF desensitization 
C) NMDA receptors 
D) caveolae uptake 
E) both A and B 
A) autophagy 
B) EGF desensitization 
C) NMDA receptors 
D) caveolae uptake 
E) both A and B

Question 5

The organelle of plant cells analogous to lysosomes in animal cells is the

Accepted Answer

A) lysosome. 
B) microsome. 
C) triskelion. 
D) vacuole. 
E) endosome. 
A) lysosome. 
B) microsome. 
C) triskelion. 
D) vacuole. 
E) endosome.

Question 6

Cells of the pancreas produce and directly release enzymes to the digestive system. The type of secretory mechanism associated with the pancreatic cells is

Accepted Answer

A) regulated secretion. 
B) transport secretion. 
C) consistent secretion. 
D) constitutive secretion. 
E) intracellular secretion. 
A) regulated secretion. 
B) transport secretion. 
C) consistent secretion. 
D) constitutive secretion. 
E) intracellular secretion.

Question 7

You are working with cells and observe transport of your target protein within a cell. You suspect that sorting conforms to the SNARE hypothesis. You, therefore, expect

Accepted Answer

A) to eventually identify transport- SNAP receptors. 
B) the protein molecules were internalized by phagocytosis. 
C) an association with clatherin- coated pits. 
D) to eventually identify vesicle- SNAP receptors. 
E) all of the above 
A) to eventually identify transport- SNAP receptors. 
B) the protein molecules were internalized by phagocytosis. 
C) an association with clatherin- coated pits. 
D) to eventually identify vesicle- SNAP receptors. 
E) all of the above

Question 8

Uptake of low- density lipoproteins (LDLs)occurs by

Accepted Answer

A) simple diffusion. 
B) pinocytosis. 
C) bulk- phase endocytosis. 
D) facilitated transport. 
E) receptor- mediated endocytosis. 
A) simple diffusion. 
B) pinocytosis. 
C) bulk- phase endocytosis. 
D) facilitated transport. 
E) receptor- mediated endocytosis.

Question 9

Compared with the proteins of the trans- Golgi, the cis- Golgi proteins would

Accepted Answer

A) be identical. 
B) be glycosylated only. 
C) be shorter in length. 
D) be glycosylated and contain amino acid modifications. 
E) contain sialic acid. 
A) be identical. 
B) be glycosylated only. 
C) be shorter in length. 
D) be glycosylated and contain amino acid modifications. 
E) contain sialic acid.

Question 10

You have genetically engineered a yeast cell to make a protein that will ultimately be secreted from the cell. If all is functioning well, in which order (first to last)do you expect find the protein in the cell until it is secreted?

Accepted Answer

A) sER -Golgi -secretory vesicle -environment 
B) nucleus -rER -Golgi -secretory vesicle -environment 
C) rER -Golgi -sER -nucleus -environment 
D) rER -secretory vesicle -Golgi -environment 
E) rER -Golgi -secretory vesicle -environment 
A) sER -Golgi -secretory vesicle -environment 
B) nucleus -rER -Golgi -secretory vesicle -environment 
C) rER -Golgi -sER -nucleus -environment 
D) rER -secretory vesicle -Golgi -environment 
E) rER -Golgi -secretory vesicle -environment

Question 11

Which of the following organelles is associated with the ability to catabolize alkanes found in oil and petroleum products?

Accepted Answer

A) smooth endoplasmic reticulum 
B) mitochondria 
C) lysosomes 
D) peroxisomes 
E) all of the above 
A) smooth endoplasmic reticulum 
B) mitochondria 
C) lysosomes 
D) peroxisomes 
E) all of the above

Question 12

In a longitudinal section of a nerve cell, at the presynaptic site you note a variety of vesicles that are anchored to the plasma membrane. The vesicles must be specialized for

Accepted Answer

A) polarized secretion. 
B) constitutive secretion. 
C) zymogen secretion. 
D) regulated secretion. 
E) none of the above 
A) polarized secretion. 
B) constitutive secretion. 
C) zymogen secretion. 
D) regulated secretion. 
E) none of the above

Question 13

All of the following statements about cellular trafficking are true EXCEPT

Accepted Answer

A) Tethering proteins mediate docking between target and vesicle. 
B) COPI- coated vesicles move materials from Golgi to the secretory vesicle. 
C) Movement may be mediated by microtubules. 
D) v- SNAREs occur in vesicles; t- SNAREs occur on target sites. 
E) COPII- coated vesicles move materials from ER to Golgi. 
A) Tethering proteins mediate docking between target and vesicle. 
B) COPI- coated vesicles move materials from Golgi to the secretory vesicle. 
C) Movement may be mediated by microtubules. 
D) v- SNAREs occur in vesicles; t- SNAREs occur on target sites. 
E) COPII- coated vesicles move materials from ER to Golgi.

Question 14

The continuous release of mucus by the epithelial cells lining the respiratory tract is an example of

Accepted Answer

A) the formation of clathrin- coated pits. 
B) phagocytosis. 
C) regulated secretion. 
D) the mucus response. 
E) constitutive secretion. 
A) the formation of clathrin- coated pits. 
B) phagocytosis. 
C) regulated secretion. 
D) the mucus response. 
E) constitutive secretion.

Question 15

The investigation of the movement of proteins and lipids to their appropriate location within a cell is known as .

Accepted Answer

endomembra

Question 16

In a lysosomal storage disease, the hydrolases of lysosomes are released from the cells, rather than being isolated into vesicles. What is one possible mechanism for this result?

Accepted Answer

A) A proton gradient within vesicles was not generated. 
B) There is a mutation in all hydrolase genes that results in loss of the signal peptide. 
C) Lysosomal enzymes were not phosphorylated in the rER. 
D) There is a lack of mannose- 6- phosphatase activity. 
E) ER was unable to produce lysosomal vesicles. 
A) A proton gradient within vesicles was not generated. 
B) There is a mutation in all hydrolase genes that results in loss of the signal peptide. 
C) Lysosomal enzymes were not phosphorylated in the rER. 
D) There is a lack of mannose- 6- phosphatase activity. 
E) ER was unable to produce lysosomal vesicles.

Question 17

Microsomes are

Accepted Answer

A) organelles of eukaryotic cells. 
B) organelles through which electrons cannot pass. 
C) artifacts generated during homogenization of cells. 
D) structures observed in cyanobacteria. 
E) too small to be seen with an electron microscope. 
A) organelles of eukaryotic cells. 
B) organelles through which electrons cannot pass. 
C) artifacts generated during homogenization of cells. 
D) structures observed in cyanobacteria. 
E) too small to be seen with an electron microscope.

Question 18

are proteins associated with clathrin- coated vesicles that are involved in the binding of vesicles to specific receptors.

Accepted Answer

The answer of are proteins associated with clathrin- coated vesicles...

Question 19

Which of the following statements is false regarding phagocytosis?

Accepted Answer

A) It involves ingestion of large particles by the cell. 
B) It involves the projection of pseudopodia. 
C) It is a method used predominantly by ameba in obtaining food. 
D) In vertebrates, macrophages and neutrophils possess this ability. 
E) It is mediated by clathrin at the plasma membrane. 
A) It involves ingestion of large particles by the cell. 
B) It involves the projection of pseudopodia. 
C) It is a method used predominantly by ameba in obtaining food. 
D) In vertebrates, macrophages and neutrophils possess this ability. 
E) It is mediated by clathrin at the plasma membrane.

Question 20

Which of the following organelles are NOT part of the endomembrane system?

Accepted Answer

A) smooth endoplasmic reticulum 
B) rough endoplasmic reticulum 
C) endosomes 
D) peroxisomes 
E) Golgi complexes 
A) smooth endoplasmic reticulum 
B) rough endoplasmic reticulum 
C) endosomes 
D) peroxisomes 
E) Golgi complexes

Exam 12: The Endomembrane System and Peroxisomes

Which of the following is associated with extracellular digestion via release of the contents of lysosomes directly to the environment?

A protein is destined to be secreted from a cell. In which of the following organelles would you expect to find the protein first?

act as proton pumps and keep the internal proton concentration of lysosomes high.

Which of the following cellular processes has/have been linked to cancer/tumor formation?

The organelle of plant cells analogous to lysosomes in animal cells is the

Cells of the pancreas produce and directly release enzymes to the digestive system. The type of secretory mechanism associated with the pancreatic cells is

You are working with cells and observe transport of your target protein within a cell. You suspect that sorting conforms to the SNARE hypothesis. You, therefore, expect

Uptake of low- density lipoproteins (LDLs)occurs by

Compared with the proteins of the trans- Golgi, the cis- Golgi proteins would

You have genetically engineered a yeast cell to make a protein that will ultimately be secreted from the cell. If all is functioning well, in which order (first to last)do you expect find the protein in the cell until it is secreted?

Which of the following organelles is associated with the ability to catabolize alkanes found in oil and petroleum products?

In a longitudinal section of a nerve cell, at the presynaptic site you note a variety of vesicles that are anchored to the plasma membrane. The vesicles must be specialized for

All of the following statements about cellular trafficking are true EXCEPT

The continuous release of mucus by the epithelial cells lining the respiratory tract is an example of

The investigation of the movement of proteins and lipids to their appropriate location within a cell is known as .

In a lysosomal storage disease, the hydrolases of lysosomes are released from the cells, rather than being isolated into vesicles. What is one possible mechanism for this result?

Microsomes are

are proteins associated with clathrin- coated vesicles that are involved in the binding of vesicles to specific receptors.

Which of the following statements is false regarding phagocytosis?

Which of the following organelles are NOT part of the endomembrane system?

A Preview of the Cell

The Chemistry of the Cell

The Macromolecules of the Cell

Cells and Organelles

Bioenergetics: The Flow of Energy in the Cell

Enzymes: The Catalysts of Life

Membranes: Their Structure, Function, and Chemistry

Transport Across Membranes: Overcoming the Permeability Barrier

Chemotrophic Energy Metabolism: Glycolysis and Fermentation

Chemotrophic Energy Metabolism: Aerobic Respiration

Phototrophic Energy Metabolism: Photosynthesis

Signal Transduction Mechanisms: I Electrical and Synaptic Signaling in Neurons

Signal Transduction Mechanisms: Ii Messengers and Receptors

Cytoskeletal Systems

Cellular Movement: Motility and Contractility

Beyond the Cell: Cell Adhesion, Cell Junctions, and Extracellular Structures

The Structural Basis of Cellular Information: DNA, Chromosomes, and the Nucleus

The Cell Cycle, Dna Replication, and Mitosis

Sexual Reproduction, Meiosis, and Genetic Recombination

Gene Expression: I the Genetic Code and Transcription

Gene Expression: II Protein Synthesis and Sorting

The Regulation of Gene Expression

Cancer Cells

Filters