Question 1

In eukaryotic organisms, a single-stranded break in the DNA is required before recombination can
begin during meiosis.

Accepted Answer

A) True 
 B)False

Question 2

Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?

Accepted Answer

A)  Ds 
B)  C 
C)  Sh 
D)  Wx 
E)  All of the answers are correct 
A)  Ds 
B)  C 
C)  Sh 
D)  Wx 
E)  All of the answers are correct

Question 3

Which of the following is incorrect regarding immunoglobins?

Accepted Answer

A)  They are produced by B cells 
B)  They recognize a specific epitope 
C)  The human genome contains a unique gene for each immunoglobin produced 
D)  They are all proteins 
A)  They are produced by B cells 
B)  They recognize a specific epitope 
C)  The human genome contains a unique gene for each immunoglobin produced 
D)  They are all proteins

Question 4

All light chain polypeptides in an immunoglobin contain which of the following?

Accepted Answer

A)  A C region 
B)  A V region 
C)  A J region 
D)  All of the answers are correct 
A)  A C region 
B)  A V region 
C)  A J region 
D)  All of the answers are correct

Question 5

Which of the following enzymes is required for a transposon to move?

Accepted Answer

A)  Integrase 
B)  Jumpase 
C)  Splicase 
D)  Transposase 
E)  None of the answers are correct 
A)  Integrase 
B)  Jumpase 
C)  Splicase 
D)  Transposase 
E)  None of the answers are correct

Question 6

The integrase enzyme is responsible for inserting bacteriophage l into the host genome.

Accepted Answer

A) True 
 B)False

Question 7

What is the selfish DNA theory?

Accepted Answer

A)  A theory that explains how DNA point mutations are repaired within the genome. 
B)  A theory that explains how transposable elements are repaired within the genome. 
C) A theory that attempts to explain the proliferation of transposable elements in a genome by comparing it to the action of a parasite. 
D)  None of the above 
A)  A theory that explains how DNA point mutations are repaired within the genome. 
B)  A theory that explains how transposable elements are repaired within the genome. 
C) A theory that attempts to explain the proliferation of transposable elements in a genome by comparing it to the action of a parasite. 
D)  None of the above

Question 8

The formation of a D-loop is associated with which of the following models of recombination?

Accepted Answer

A)  Double-stranded break model 
B)  Holliday model 
C)  Single-stranded break model 
D)  All of the answers are correct 
A)  Double-stranded break model 
B)  Holliday model 
C)  Single-stranded break model 
D)  All of the answers are correct

Question 9

RAG1 and RAG2 proteins are associated with which of the following?

Accepted Answer

A)  Recombination during prophase I of meiosis 
B)  Nucleotide excision repair 
C)  Transposition 
D)  Integration of a bacteriophage into the host genome 
E)  Site-specific recombination in antibody genes 
A)  Recombination during prophase I of meiosis 
B)  Nucleotide excision repair 
C)  Transposition 
D)  Integration of a bacteriophage into the host genome 
E)  Site-specific recombination in antibody genes

Question 10

Insertion sequences can be identified by which of the following?

Accepted Answer

A)  Presence of an integrase enzyme 
B)  High level of mutation 
C)  Presence of inverted repeats at the end of the sequence 
D)  Presence of a reverse transcriptase enzyme 
E)  All of the answers are correct 
A)  Presence of an integrase enzyme 
B)  High level of mutation 
C)  Presence of inverted repeats at the end of the sequence 
D)  Presence of a reverse transcriptase enzyme 
E)  All of the answers are correct

Question 11

Transposons that utilize an RNA intermediate for transposition are called .

Accepted Answer

A)  Retro elements 
B)  Retroposons 
C)  Retrotransposons 
D)  All of the answers are correct 
A)  Retro elements 
B)  Retroposons 
C)  Retrotransposons 
D)  All of the answers are correct

Question 12

An attachment site for bacteriophage l have which of the following characteristic(s)?

Accepted Answer

A)  Specific proteins in the cell membrane 
B)  A unique set of phospholipids that identify the organelle of interest 
C)  A lack of a cell wall 
D)  A specific DNA sequence that is recognized by the integrase enzyme 
E)  None of the answers are correct 
A)  Specific proteins in the cell membrane 
B)  A unique set of phospholipids that identify the organelle of interest 
C)  A lack of a cell wall 
D)  A specific DNA sequence that is recognized by the integrase enzyme 
E)  None of the answers are correct

Question 13

A bacteriophage that has integrated into the bacterial chromosome is called a prophage.

Accepted Answer

A) True 
 B)False

Question 14

As a researcher, you have identified a potential transposable element that contains both a transposase and resolvase enzyme. Which of the following types of transposons would you assign it to based on this information?

Accepted Answer

A)  Composite transposon 
B)  Non-viral retro element 
C)  Viral-like retro element 
D)  Replicative transposon 
E)  Insertion sequence 
A)  Composite transposon 
B)  Non-viral retro element 
C)  Viral-like retro element 
D)  Replicative transposon 
E)  Insertion sequence

Question 15

The individual who first proposed the existence of transposable elements was .

Accepted Answer

A)  Sturtevant 
B)  Morgan 
C)  McClintock 
D)  Franklin 
E)  Watson 
A)  Sturtevant 
B)  Morgan 
C)  McClintock 
D)  Franklin 
E)  Watson

Question 16

Transposase is involved with removing the transposable element from its current location.

Accepted Answer

A) True 
 B)False

Question 17

A composite transposon will contain only genes that are necessary for transposition.

Accepted Answer

A) True 
 B)False

Question 18

To date, there are not any indications that transposable elements offer a selective advantage to a
species.

Accepted Answer

A) True 
 B)False

Question 19

Which of the following processes accounts for the tremendous variation in antibody structure?

Accepted Answer

A)  RNA editing 
B)  Site-specific recombination 
C)  Integrase activity 
D)  Physiological adaptation 
E)  Hot spots of mutation in the immunoglobin genes 
A)  RNA editing 
B)  Site-specific recombination 
C)  Integrase activity 
D)  Physiological adaptation 
E)  Hot spots of mutation in the immunoglobin genes

Exam 17: Recombination and Transposition at the Molecular

In eukaryotic organisms, a single-stranded break in the DNA is required before recombination can begin during meiosis.

Which of the following genes was mobile in McClintock's experiments with mutable sites in corn?

Which of the following is incorrect regarding immunoglobins?

All light chain polypeptides in an immunoglobin contain which of the following?

Which of the following enzymes is required for a transposon to move?

The integrase enzyme is responsible for inserting bacteriophage l into the host genome.

What is the selfish DNA theory?

The formation of a D-loop is associated with which of the following models of recombination?

RAG1 and RAG2 proteins are associated with which of the following?

Insertion sequences can be identified by which of the following?

Transposons that utilize an RNA intermediate for transposition are called .

An attachment site for bacteriophage l have which of the following characteristic(s)?

A bacteriophage that has integrated into the bacterial chromosome is called a prophage.

As a researcher, you have identified a potential transposable element that contains both a transposase and resolvase enzyme. Which of the following types of transposons would you assign it to based on this information?

The individual who first proposed the existence of transposable elements was .

Transposase is involved with removing the transposable element from its current location.

A composite transposon will contain only genes that are necessary for transposition.

To date, there are not any indications that transposable elements offer a selective advantage to a species.

Which of the following processes accounts for the tremendous variation in antibody structure?

Overview of Genetics

Mendelian Inheritance

Reproduction and Chromosome Transmission

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and

Variation in Chromosome Structure and Number

Molecular Structure of Dna and Rna

Chromosome Organization and Molecular Structure

Dna Replication

Gene Transcription and Rna Modification

Translation of Mrna

Gene Regulation in Bacteria and Bacteriophages

Gene Regulation in Eukaryotes

Gene Mutation and Dna Repair

Recombinant Dna Technology

Biotechnology

Genomics I: Analysis of Dna

Genomics II: Functional Genomics, Proteomics, and

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

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