Question 1

The production of gene families, such as the globin genes is the result of .

Accepted Answer

A)  Inversions 
B)  Deficiencies 
C)  Gene duplications 
D)  Simple translocations 
E)  None of the answers are correct 
A)  Inversions 
B)  Deficiencies 
C)  Gene duplications 
D)  Simple translocations 
E)  None of the answers are correct

Question 2

The term refers to genetic differences between members of the same species.

Accepted Answer

A)  chromosomal variation 
B)  genetic variation 
C)  chromosomal deletions 
D)  polyploidy 
A)  chromosomal variation 
B)  genetic variation 
C)  chromosomal deletions 
D)  polyploidy

Question 3

Gene duplications may be caused by which of the following?

Accepted Answer

A)  The crossing over of misaligned chromosomes 
B)  Deletion of important genetic information 
C)  Reciprocal translocations 
D)  Position effect 
E)  None of the answers are correct 
A)  The crossing over of misaligned chromosomes 
B)  Deletion of important genetic information 
C)  Reciprocal translocations 
D)  Position effect 
E)  None of the answers are correct

Question 4

The polytene chromosomes of Drosophila are an example of .

Accepted Answer

A)  Aneuploidy 
B)  Polyploidy 
C)  Translocations 
D)  Inversion loops 
E)  None of the answers are correct 
A)  Aneuploidy 
B)  Polyploidy 
C)  Translocations 
D)  Inversion loops 
E)  None of the answers are correct

Question 5

Homologous genes within a species are called paralogs.

Accepted Answer

A) True 
 B)False

Question 6

Which of following algebraic expressions would be used to denote a trisomic organism?

Accepted Answer

A)  3n 
B)  2n - 1 
C)  2n + 1 
D)  2n + 2 
A)  3n 
B)  2n - 1 
C)  2n + 1 
D)  2n + 2

Question 7

The short arm of a chromosome is denoted by the letter and the long arm by the letter .

Accepted Answer

A)  p, q 
B)  s, l 
C)  q, p 
D)  c, d 
A)  p, q 
B)  s, l 
C)  q, p 
D)  c, d

Question 8

Klinefelter and Turner syndromes are examples of which of the following?

Accepted Answer

A)  Sex chromosome aneuploidy 
B)  Autosomal aneuploidy 
C)  Reciprocal translocations 
D)  Paracentric inversions 
A)  Sex chromosome aneuploidy 
B)  Autosomal aneuploidy 
C)  Reciprocal translocations 
D)  Paracentric inversions

Question 9

Given the following sequence of genes on a chromosome, determine what change in chromosome structure occurred. (the * indicates the centromere)
Before A B C D * E F G H after A B C D * E F E F G H

Accepted Answer

A)  Terminal deficiency 
B)  Interstitial deficiency 
C)  Inversion 
D)  Gene duplication 
A)  Terminal deficiency 
B)  Interstitial deficiency 
C)  Inversion 
D)  Gene duplication

Question 10

Due to the formation of an inversion loop, sections of DNA may either be duplicated or deleted
depending on the size of the inversion.

Accepted Answer

A) True 
 B)False

Question 11

The majority of autosomal aneuploid conditions are lethal, but sex chromosome aneuploids are
usually not lethal.

Accepted Answer

A) True 
 B)False

Question 12

Chromosomes may be identified based on which of the following characteristics?

Accepted Answer

A)  Location of the centromere 
B)  Banding patterns 
C)  Size of the chromosome 
D)  All of the answers are correct 
A)  Location of the centromere 
B)  Banding patterns 
C)  Size of the chromosome 
D)  All of the answers are correct

Question 13

Human genetic diseases such a Cri-du-chat, Angelman syndrome and Prader-Willi syndrome are the result of which of the following?

Accepted Answer

A)  Translocations 
B)  Duplications 
C)  Deletions 
D)  Inversions 
A)  Translocations 
B)  Duplications 
C)  Deletions 
D)  Inversions

Question 14

An inversion heterozygote contains which of the following?

Accepted Answer

A)  Two homologous chromosomes with inversions 
B)  Two normal chromosomes 
C)  One normal chromosome and one chromosome with an inversion 
D)  None of the answers are correct 
A)  Two homologous chromosomes with inversions 
B)  Two normal chromosomes 
C)  One normal chromosome and one chromosome with an inversion 
D)  None of the answers are correct

Question 15

The ends of chromosomes have areas of repeated DNA called centromeres.

Accepted Answer

A) True 
 B)False

Question 16

Which of the following would have the shortest p arm of the chromosome?

Accepted Answer

A)  Acrocentic 
B)  Metacentric 
C)  Telocentric 
D)  Submetacentric 
E)  All of the answers would be equal 
A)  Acrocentic 
B)  Metacentric 
C)  Telocentric 
D)  Submetacentric 
E)  All of the answers would be equal

Question 17

A photographic representation of the chromosomes of an organism is called a .

Accepted Answer

A)  allele variation 
B)  chromosomal spreading 
C)  chromosome picture 
D)  karyotype 
A)  allele variation 
B)  chromosomal spreading 
C)  chromosome picture 
D)  karyotype

Question 18

A translocation represents when a piece of one chromosome is attached to another chromosome.

Accepted Answer

A)  simple 
B)  complex 
C)  reciprocal 
D)  balanced 
A)  simple 
B)  complex 
C)  reciprocal 
D)  balanced

Question 19

The effects of a deficiency on an organism is dependent on the size of the deletion and the importance
of the missing genetic material to the organism.

Accepted Answer

A) True 
 B)False

Question 20

Variations in chromosome structure are important for which of the following reason(s)?

Accepted Answer

A)  Evolution of new species 
B)  May result in the production of abnormal offspring 
C)  May alter the phenotype of an organism 
D)  All of the answers are correct 
A)  Evolution of new species 
B)  May result in the production of abnormal offspring 
C)  May alter the phenotype of an organism 
D)  All of the answers are correct

Exam 8: Variation in Chromosome Structure and Number

The production of gene families, such as the globin genes is the result of .

The term refers to genetic differences between members of the same species.

Gene duplications may be caused by which of the following?

The polytene chromosomes of Drosophila are an example of .

Homologous genes within a species are called paralogs.

Which of following algebraic expressions would be used to denote a trisomic organism?

The short arm of a chromosome is denoted by the letter and the long arm by the letter .

Klinefelter and Turner syndromes are examples of which of the following?

Given the following sequence of genes on a chromosome, determine what change in chromosome structure occurred. (the * indicates the centromere) Before A B C D * E F G H after A B C D * E F E F G H

Due to the formation of an inversion loop, sections of DNA may either be duplicated or deleted depending on the size of the inversion.

The majority of autosomal aneuploid conditions are lethal, but sex chromosome aneuploids are usually not lethal.

Chromosomes may be identified based on which of the following characteristics?

Human genetic diseases such a Cri-du-chat, Angelman syndrome and Prader-Willi syndrome are the result of which of the following?

An inversion heterozygote contains which of the following?

The ends of chromosomes have areas of repeated DNA called centromeres.

Which of the following would have the shortest p arm of the chromosome?

A photographic representation of the chromosomes of an organism is called a .

A translocation represents when a piece of one chromosome is attached to another chromosome.

The effects of a deficiency on an organism is dependent on the size of the deletion and the importance of the missing genetic material to the organism.

Variations in chromosome structure are important for which of the following reason(s)?

Overview of Genetics

Mendelian Inheritance

Reproduction and Chromosome Transmission

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and

Molecular Structure of Dna and Rna

Chromosome Organization and Molecular Structure

Dna Replication

Gene Transcription and Rna Modification

Translation of Mrna

Gene Regulation in Bacteria and Bacteriophages

Gene Regulation in Eukaryotes

Gene Mutation and Dna Repair

Recombination and Transposition at the Molecular

Recombinant Dna Technology

Biotechnology

Genomics I: Analysis of Dna

Genomics II: Functional Genomics, Proteomics, and

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

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