Question 1

The lac operon is an example of _______ operon.

Accepted Answer

A) a noninducible 
B) a constitutive 
C) an inducible 
D) a repressible 
E) an irrepressible 
A) a noninducible 
B) a constitutive 
C) an inducible 
D) a repressible 
E) an irrepressible

Question 2

During a cloning experiment, the nucleus of a differentiated cell ________. (Select all correct choices)

Accepted Answer

A) is able to stop expressing the genes of the adult tissue from which it is taken 
B) starts expressing the genes of the adult tissue from which it was taken after transplantation 
C) begins to selectively express the genes that are appropriate for the activated egg in which it suddenly finds itself 
D) begins to selectively express the genes that are appropriate for the adult tissue in which it suddenly finds itself 
A) is able to stop expressing the genes of the adult tissue from which it is taken 
B) starts expressing the genes of the adult tissue from which it was taken after transplantation 
C) begins to selectively express the genes that are appropriate for the activated egg in which it suddenly finds itself 
D) begins to selectively express the genes that are appropriate for the adult tissue in which it suddenly finds itself

Question 3

The enzymes that remove acetyl groups from histones in the chromatin are ________.

Accepted Answer

A) histone acetyltransferases 
B) histone deacetylases 
C) histone acetylases 
D) histone methylases 
E) methylacetyltransferases 
A) histone acetyltransferases 
B) histone deacetylases 
C) histone acetylases 
D) histone methylases 
E) methylacetyltransferases

Question 4

What role are microfilaments thought to play in the localization of oskar and bicoid mRNAs in the fruit fly oocytes?

Accepted Answer

A) They are thought to anchor mRNAs in position after they have arrived at their destination. 
B) They move these mRNAs to their final destination. 
C) They play no role in localization or anchoring the mRNAs in the proper position. 
D) They compress the mRNAs. 
E) They increase the stability of mRNAs. 
A) They are thought to anchor mRNAs in position after they have arrived at their destination. 
B) They move these mRNAs to their final destination. 
C) They play no role in localization or anchoring the mRNAs in the proper position. 
D) They compress the mRNAs. 
E) They increase the stability of mRNAs.

Question 5

What is the name of the gene responsible for the inactivation of the X chromosome?

Accepted Answer

A) INAC 
B) XIST 
C) 1STX 
D) IRS 
E) XCHR 
A) INAC 
B) XIST 
C) 1STX 
D) IRS 
E) XCHR

Question 6

When present, the TATA, CAAT and GC boxes are typically found within 100 - 150 bp upstream from the transcription start site. Due to their closeness to the start of gene, they are often called ______.

Accepted Answer

A) distal promoter elements 
B) proximal promoter elements 
C) central promoter sites 
D) primary promoter elements 
E) primary promoter sites 
A) distal promoter elements 
B) proximal promoter elements 
C) central promoter sites 
D) primary promoter elements 
E) primary promoter sites

Question 7

Covalent linkage to what highly-conserved molecule marks proteins for destruction?

Accepted Answer

A) chaperonin 
B) actin 
C) polyubiquitin 
D) cyclin 
E) dystrophin 
A) chaperonin 
B) actin 
C) polyubiquitin 
D) cyclin 
E) dystrophin

Question 8

When an importin α/β complex carries a protein destined to move into the nucleus, what does it bind to when it comes to the outer surface of the nucleus near the nuclear pore complex?

Accepted Answer

A) the torus 
B) the outer ring of the nuclear pore complex 
C) the inner ring of the nuclear pore complex 
D) cytoplasmic filaments that extend from the outer ring of the nuclear pore complex 
E) the transporter 
A) the torus 
B) the outer ring of the nuclear pore complex 
C) the inner ring of the nuclear pore complex 
D) cytoplasmic filaments that extend from the outer ring of the nuclear pore complex 
E) the transporter

Question 9

Which type of molecule binds at the core promoter sites in association with RNA polymerase?

Accepted Answer

A) general transcription factors 
B) sequence-specific transcription factors 
C) elongation factors 
D) initiation factors 
E) termination factors 
A) general transcription factors 
B) sequence-specific transcription factors 
C) elongation factors 
D) initiation factors 
E) termination factors

Question 10

Which transcription factor helps to activate genes needed for cell division?

Accepted Answer

A) Egr 
B) Csn 
C) GATA 
D) trp 
A) Egr 
B) Csn 
C) GATA 
D) trp

Question 11

What experimental evidence suggests that the N-terminal tails of histones participate in the formation of higher-order chromatin structure?

Accepted Answer

A) The tails cause histones to denature. 
B) The tails when acetylated cause the dissolution of the 30-nm fibers. 
C) Chromatin fibers with histones lacking their tails cannot fold into higher-order fibers. 
D) Chromatin fibers with histones possessing longer tails cannot fold into higher-order fibers. 
E) Chromatin fibers lacking tails are shorter. 
A) The tails cause histones to denature. 
B) The tails when acetylated cause the dissolution of the 30-nm fibers. 
C) Chromatin fibers with histones lacking their tails cannot fold into higher-order fibers. 
D) Chromatin fibers with histones possessing longer tails cannot fold into higher-order fibers. 
E) Chromatin fibers lacking tails are shorter.

Question 12

The inactive mRNAs that are stored in an egg prior to fertilization typically have ________.

Accepted Answer

A) lengthened 5' UTRs 
B) lengthened poly(
A) tails 
C) shortened poly(
A) tails 
D) many lipids associated with them 
E) shortened 5' UTRs 
A) lengthened 5' UTRs 
B) lengthened poly(
A) tails 
C) shortened poly(
A) tails 
D) many lipids associated with them 
E) shortened 5' UTRs

Question 13

What evidence suggests that RNAi plays a role in heterochromatization?

Accepted Answer

A) Deletion of RNAi components impairs both methylation of histone H3K9 and heterochromatization. 
B) Addition of RNAi components impairs both methylation of histone H3K9 and heterochromatization. 
C) Deletion of RNAi components enhances both methylation of histone H3K9 and heterochromatization. 
D) Mutation of RNAi components denatures both methylation of histone H3K9 and heterochromatization. 
A) Deletion of RNAi components impairs both methylation of histone H3K9 and heterochromatization. 
B) Addition of RNAi components impairs both methylation of histone H3K9 and heterochromatization. 
C) Deletion of RNAi components enhances both methylation of histone H3K9 and heterochromatization. 
D) Mutation of RNAi components denatures both methylation of histone H3K9 and heterochromatization.

Question 14

When an adenine (A)is converted to an inosine (I), how is it subsequently read by the translational machinery?

Accepted Answer

A) It is read as a guanine (G). 
B) It is read as a cytosine (
C) . 
C) It is read as a uracil (U). 
D) It is read as a thymine (T). 
A) It is read as a guanine (G). 
B) It is read as a cytosine (
C) . 
C) It is read as a uracil (U). 
D) It is read as a thymine (T).

Question 15

The localization of mRNAs is mediated by specific proteins that recognize mRNA localization sequences on the mRNAs. Select the molecule or molecular region which is NOT believed to be involved in localization.

Accepted Answer

A) 3' UTR of mRNA 
B) collagen 
C) microtubules 
D) kinesin I motor protein 
E) microfilaments 
A) 3' UTR of mRNA 
B) collagen 
C) microtubules 
D) kinesin I motor protein 
E) microfilaments

Question 16

The fact that chromosomes should become shorter and shorter with each round of cell division is referred to as the ________.

Accepted Answer

A) shortening contradiction 
B) the replication paradox 
C) the short end hypothesis 
D) the truncated end problem 
E) the end-replication problem 
A) shortening contradiction 
B) the replication paradox 
C) the short end hypothesis 
D) the truncated end problem 
E) the end-replication problem

Question 17

Which of the following would be the most acceptable explanation for why cloned animals actually have telomeres of normal length on their chromosomes?

Accepted Answer

A) The telomeres were elongated before transfer to the egg by telomerase in egg cell cytoplasm. 
B) The telomeres were elongated after transfer to the egg by telomerase in egg cell cytoplasm. 
C) The telomeres were shortened before transfer to the egg by telomerase in egg cell cytoplasm. 
D) The telomeres were shortened after transfer to the egg by telomerase in egg cell cytoplasm. 
E) The telomeres were replaced prior to mitosis by DNA repair. 
A) The telomeres were elongated before transfer to the egg by telomerase in egg cell cytoplasm. 
B) The telomeres were elongated after transfer to the egg by telomerase in egg cell cytoplasm. 
C) The telomeres were shortened before transfer to the egg by telomerase in egg cell cytoplasm. 
D) The telomeres were shortened after transfer to the egg by telomerase in egg cell cytoplasm. 
E) The telomeres were replaced prior to mitosis by DNA repair.

Question 18

In gene expression profiling by microarray analysis, ____ sequences produced from mRNA are hybridized with ____ sequences that have been spotted onto a glass slide.

Accepted Answer

A) cDNA, complementary RNA 
B) cDNA, complementary DNA 
C) RNA, complementary 
D) intron, exon 
E) short, long 
A) cDNA, complementary RNA 
B) cDNA, complementary DNA 
C) RNA, complementary 
D) intron, exon 
E) short, long

Question 19

When a regulatory protein inhibits transcription, this is known as _________________.

Accepted Answer

A) positive control 
B) negative control 
C) averaged control 
D) circumspect control 
E) neutral control 
A) positive control 
B) negative control 
C) averaged control 
D) circumspect control 
E) neutral control

Question 20

You are working with adult mouse fibroblast cells. The genes for transcription factors from pluripotent stem cells are transduced into the adult fibroblast cells as part of viral vectors in various combinations, and once inside the cells they are expressed. Cells are produced that are capable of dividing indefinitely in culture and of differentiating into all of the various types of the body's cells. What are these new cells called? (Select all correct choices)

Accepted Answer

A) iPS cells 
B) white blood cells 
C) induced pluripotent cells 
D) infracted pluripotent cells 
E) infant-derived pluripotent cells 
A) iPS cells 
B) white blood cells 
C) induced pluripotent cells 
D) infracted pluripotent cells 
E) infant-derived pluripotent cells

The lac operon is an example of _______ operon.

During a cloning experiment, the nucleus of a differentiated cell ________. (Select all correct choices)

The enzymes that remove acetyl groups from histones in the chromatin are ________.

What role are microfilaments thought to play in the localization of oskar and bicoid mRNAs in the fruit fly oocytes?

What is the name of the gene responsible for the inactivation of the X chromosome?

When present, the TATA, CAAT and GC boxes are typically found within 100 - 150 bp upstream from the transcription start site. Due to their closeness to the start of gene, they are often called ______.

Covalent linkage to what highly-conserved molecule marks proteins for destruction?

When an importin α/β complex carries a protein destined to move into the nucleus, what does it bind to when it comes to the outer surface of the nucleus near the nuclear pore complex?

Which type of molecule binds at the core promoter sites in association with RNA polymerase?

Which transcription factor helps to activate genes needed for cell division?

What experimental evidence suggests that the N-terminal tails of histones participate in the formation of higher-order chromatin structure?

The inactive mRNAs that are stored in an egg prior to fertilization typically have ________.

What evidence suggests that RNAi plays a role in heterochromatization?

When an adenine (A)is converted to an inosine (I), how is it subsequently read by the translational machinery?

The localization of mRNAs is mediated by specific proteins that recognize mRNA localization sequences on the mRNAs. Select the molecule or molecular region which is NOT believed to be involved in localization.

The fact that chromosomes should become shorter and shorter with each round of cell division is referred to as the ________.

Which of the following would be the most acceptable explanation for why cloned animals actually have telomeres of normal length on their chromosomes?

In gene expression profiling by microarray analysis, sequences produced from mRNA are hybridized with sequences that have been spotted onto a glass slide.

When a regulatory protein inhibits transcription, this is known as _________________.

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics, Enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, Function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

Exam 12: Control of Gene Expression

The lac operon is an example of _______ operon.

During a cloning experiment, the nucleus of a differentiated cell ________. (Select all correct choices)

The enzymes that remove acetyl groups from histones in the chromatin are ________.

What role are microfilaments thought to play in the localization of oskar and bicoid mRNAs in the fruit fly oocytes?

What is the name of the gene responsible for the inactivation of the X chromosome?

When present, the TATA, CAAT and GC boxes are typically found within 100 - 150 bp upstream from the transcription start site. Due to their closeness to the start of gene, they are often called ______.

Covalent linkage to what highly-conserved molecule marks proteins for destruction?

When an importin α/β complex carries a protein destined to move into the nucleus, what does it bind to when it comes to the outer surface of the nucleus near the nuclear pore complex?

Which type of molecule binds at the core promoter sites in association with RNA polymerase?

Which transcription factor helps to activate genes needed for cell division?

What experimental evidence suggests that the N-terminal tails of histones participate in the formation of higher-order chromatin structure?

The inactive mRNAs that are stored in an egg prior to fertilization typically have ________.

What evidence suggests that RNAi plays a role in heterochromatization?

When an adenine (A)is converted to an inosine (I), how is it subsequently read by the translational machinery?

The localization of mRNAs is mediated by specific proteins that recognize mRNA localization sequences on the mRNAs. Select the molecule or molecular region which is NOT believed to be involved in localization.

The fact that chromosomes should become shorter and shorter with each round of cell division is referred to as the ________.

Which of the following would be the most acceptable explanation for why cloned animals actually have telomeres of normal length on their chromosomes?

In gene expression profiling by microarray analysis, ____ sequences produced from mRNA are hybridized with ____ sequences that have been spotted onto a glass slide.

When a regulatory protein inhibits transcription, this is known as _________________.

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics, Enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, Function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

In gene expression profiling by microarray analysis, sequences produced from mRNA are hybridized with sequences that have been spotted onto a glass slide.