Exam 12: Control of Gene Expression

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Which of the following does NOT accurately describe the contents of the nucleus?

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With what structure is the outer membrane of the nuclear envelope continuous?

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What domain of a transcription factor is responsible for recognizing and associating with specific DNA base pair sequences?

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How do the proteins involved in controlling transcription of genes related to flower development associate with one another?

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The helix-loop-helix (HLH)motif is often preceded by a stretch of highly ______ amino acids whose ______ charged side chains contact DNA and determine the transcription factor's sequence specificity.

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You are working with adult mouse fibroblast cells. The genes for transcription factors from pluripotent stem cells are transduced into the adult fibroblast cells as part of viral vectors in various combinations, and once inside the cells they are expressed. What results would you expect to obtain? (Select all correct choices)

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Which of the traits below is characteristic of the classical nuclear localization signals?

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A section of a bacterial chromosome in which genes for the enzymes of a particular metabolic pathway are clustered together in a functional complex under coordinate control is called ______.

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Transcription factors bound at the enhancer stimulate the initiation of transcription at the core promoter through the action of intermediaries called _____.

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You are interpreting data on a DNA chip or microarray. You expose the chip to a mixture of two cDNA populations: one from cells that were not treated with a glucocorticoid hormone (untreated controls; labeled with a red fluorescent dye)and a population from cells that were treated with glucocorticoid hormones (glucocorticoid-treated; labeled with green fluorescent dye). You look at a spot on the chip representing the gene for phosphoenolase, a gene that is turned off by glucocorticoid treatment, but is expressed in control, untreated cells. What color should the spot representing the phosphoenolase gene be?

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What is thought to maintain X chromosome inactivation?

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How do allolactose and lactose differ?

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Which of the following is NOT a general description of one of the gene expression regulation mechanisms that operate in eukaryotic organisms?

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The success of cloning experiments led to all of the following conclusions EXCEPT:

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In mRNA editing, to which nitrogenous bases is adenine converted by the enzymatic removal of an amino group?

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Evidence suggests that ________ of __________ groups from nucleosomes in the wake of an elongating RNA polymerase prevents inappropriate __________ within the internal coding region of a gene.

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The combination of a basic stretch of amino acids and a leucine zipper is known as a(n)_____ motif.

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You attempt deletion mapping of a part of the promoter region of a particular gene. \ You remove a short sequence of nucleotides. Once the altered DNA is transfected into cells, the cells are able to transcribe the transfected DNA in a normal fashion. What do you conclude?

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How many adenosine residues must the poly(A)tail have to short enough to cause the mRNA to be degraded rapidly?

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A plant breeder is looking to create a novel bloom type highlighting the intricate colors found in the carpals of a particular lily by reducing the stamens. He is not concerned about plant fertility. What would be his most efficient way to produce new candidate plants?

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