Question 1

Match the following. Chemotherapeutic agents are placed into various classes of drug action
-Corticosteroids

Accepted Answer

A) Cell cycle active, phase-specific 
B) Cell cycle active, phase-nonspecific 
C) Non-cell cycle active 
A) Cell cycle active, phase-specific 
B) Cell cycle active, phase-nonspecific 
C) Non-cell cycle active C

Question 2

Tumor immunity has the following general feature-the normal immune response frequently prevents the growth of tumors.

Accepted Answer

A) True 
 B)False  False

Question 3

Match the characteristics with the type of tumor.
-Metastasis

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant B

Question 4

Cancer results from a series of genetic alterations that can include inactivation of oncogenes that promote cell growth.

Accepted Answer

A) True 
 B)False

Question 5

Tumor immunity has the following general feature-tumors express antigens that are recognized as foreign by the immune system of the tumor-bearing host.

Accepted Answer

A) True 
 B)False

Question 6

Tumors are neoplasms.

Accepted Answer

A) True 
 B)False

Question 7

Match the antigens with the appropriate description.
-Tumor-specific antigens

Accepted Answer

A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism 
A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism

Question 8

The most common cause of pediatric cancer deaths is

Accepted Answer

A) acute lymphoblastic leukemia. 
B) tumors of the central and sympathetic nervous system. 
C) malignant lymphoma. 
D) renal tumors. 
A) acute lymphoblastic leukemia. 
B) tumors of the central and sympathetic nervous system. 
C) malignant lymphoma. 
D) renal tumors.

Question 9

Most tumors are of connective tissue origin.

Accepted Answer

A) True 
 B)False

Question 10

Match the characteristics with the type of tumor.
-Resembling the parent tissue

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant

Question 11

Next-generation sequencing techniques have clinical applications in the recognition and treatment of cancer because they allow the sequencing of entire cancer genomes.

Accepted Answer

A) True 
 B)False

Question 12

A cancer-disposing gene, BRCA2, is associated with a very high risk of

Accepted Answer

A) uterine cancer. 
B) endometrial cancer. 
C) breast cancer. 
D) None of the above. 
A) uterine cancer. 
B) endometrial cancer. 
C) breast cancer. 
D) None of the above.

Question 13

Cancer results from a series of genetic alterations that can include affecting a host's ability to repair resulting damage to DNA.

Accepted Answer

A) True 
 B)False

Question 14

Match the antigens with the appropriate description.
-Tumor-associated antigens

Accepted Answer

A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism 
A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism

Question 15

Match the characteristics with the type of tumor.
-Increase in number of cells that accumulate

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant

Question 16

Match the following. Chemotherapeutic agents are placed into various classes of drug action
-Act on the S, G2, or M phase of mitosis

Accepted Answer

A) Cell cycle active, phase-specific 
B) Cell cycle active, phase-nonspecific 
C) Non-cell cycle active 
A) Cell cycle active, phase-specific 
B) Cell cycle active, phase-nonspecific 
C) Non-cell cycle active

Question 17

Match the antigens with the appropriate description.
-Spontaneous tumor antigens

Accepted Answer

A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism 
A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism

Question 18

A new positive prognostic indicator for primary breast cancer in women is

Accepted Answer

A) a good gene expression signature. 
B) a low S phase tumor cell content. 
C) diploid DNA content of tumor cells. 
D) All of the above. 
A) a good gene expression signature. 
B) a low S phase tumor cell content. 
C) diploid DNA content of tumor cells. 
D) All of the above.

Question 19

Match the characteristics with the type of tumor.
-Minimal mitotic activity

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant

Question 20

Tumor immunity has the following general feature-the immune system can be stimulated to kill tumor cells and rid the host of the tumor.

Accepted Answer

A) True 
 B)False

Exam 31: Tumor Immunology and Up-To-Date Applications of Next-Generation Sequencing

Match the following. Chemotherapeutic agents are placed into various classes of drug action -Corticosteroids

Tumor immunity has the following general feature-the normal immune response frequently prevents the growth of tumors.

Match the characteristics with the type of tumor. -Metastasis

Cancer results from a series of genetic alterations that can include inactivation of oncogenes that promote cell growth.

Tumor immunity has the following general feature-tumors express antigens that are recognized as foreign by the immune system of the tumor-bearing host.

Tumors are neoplasms.

Match the antigens with the appropriate description. -Tumor-specific antigens

The most common cause of pediatric cancer deaths is

Most tumors are of connective tissue origin.

Match the characteristics with the type of tumor. -Resembling the parent tissue

Next-generation sequencing techniques have clinical applications in the recognition and treatment of cancer because they allow the sequencing of entire cancer genomes.

A cancer-disposing gene, BRCA2, is associated with a very high risk of

Cancer results from a series of genetic alterations that can include affecting a host's ability to repair resulting damage to DNA.

Match the antigens with the appropriate description. -Tumor-associated antigens

Match the characteristics with the type of tumor. -Increase in number of cells that accumulate

Match the following. Chemotherapeutic agents are placed into various classes of drug action -Act on the S, G2, or M phase of mitosis

Match the antigens with the appropriate description. -Spontaneous tumor antigens

A new positive prognostic indicator for primary breast cancer in women is

Match the characteristics with the type of tumor. -Minimal mitotic activity

Tumor immunity has the following general feature-the immune system can be stimulated to kill tumor cells and rid the host of the tumor.

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Rapid Testing

Precipitation and Particle Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Flow Cytometry

Molecular Laboratory Techniques

Infectious Diseases: Traditional and Alternate Diagnostic Techniques

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Primary and Acquired Immune Deficiency Syndromes

Hypersensitivity Reactions

Immunoproliferative Disorders

Tolerance, Autoimmunity, and Autoimmune Diseases

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Transplantation: Hla, Solid Organ, and Hematopoietic Stem Cells

Primer on Vaccines

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