Exam 8: DNA Structure and Chromosomal Organization

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What role might nucleosomes play in chromosome structure? What are the dimensions of the problem in packing a diploid amount of DNA into a typical nucleus?

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A _______________ molecule connects two ribose sugars together in an RNA molecule.

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Both ________________ and _________________ have a two-ringed chemical structure.

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If a DNA molecule was a ladder, the rungs of the ladder would be formed by the ____________ and the rails of the ladder would be formed by the ______________.

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DNA replication occurs during cytokinesis.

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In addition to the nucleosome, DNA in a chromosome has several more levels of folding and compaction.

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DNA is made up of a linear array of ____________________.

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Describe the structure of nucleosomes.

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Match the following researchers with their discovery.
The structure of DNA
Chargaff
The genetic material is DNA, not protein
Griffith
Transforming factor can be transferred between dead and living bacteria
Avery
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The structure of DNA
Chargaff
The genetic material is DNA, not protein
Griffith
Transforming factor can be transferred between dead and living bacteria
Avery
In a DNA molecule, the amount of adenine equals the amount of cytosine
Crick
The transforming factor is chromatin
Miescher
The nucleus contains nuclein, which contains DNA
Chase
The genetic code
None of these
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Very rarely, DNA polymerase makes mistakes and during replication inserts a "wrong" (non-complementary) nucleotide into the new DNA strand (e.g., inserts a G opposite a T). What are the consequences of such errors?

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The nitrogenous bases of DNA stores genetic information.

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RNA differs from DNA in

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The two strands of each polynucleotide chain in DNA are identical.

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