Exam 7: Replication, Maintenance, and Rearrangements of Genomic Dna

The leading and lagging strands at a replication fork are synthesized in opposite directions, but both are synthesized in a continuous manner.

Mitochondria have their own unique DNA polymerase.

A major difference between immunoglobulin heavy chains and light chains is that heavy chains contain _______ regions.

The most common cause of skin cancer is damage to DNA by

Explain how a prokaryotic chromosome can replicate and divide normally with no telomeres and only one origin of replication.

How does nucleotide-excision repair differ from base-excision repair?

Origins of replication are the

Gene amplification is

The function of topoisomerase II is to

Mutations in the genes for RAG1 and RAG2 would most likely have an effect on

T cell receptors

Cultured cells from xeroderma pigmentosum patients were unable to carry out

Why does the synthesis of Okazaki fragments require an RNA primer?

What are the functions of origins of replication?

DNA replication starts at sites called replication forks.

What are the functions of telomeres?

Recombination of DNA strands is important because it can

DNA polymerase requires a primer and cannot initiate synthesis de novo. What serves as a primer for DNA replication?

All known DNA polymerases synthesize DNA in the 5ʹ to 3ʹ direction.

Which region is not part of the immunoglobulin light chain?