Question 1

Select the stages of transcription.

Accepted Answer

A)  initiation 
B)  elongation 
C)  termination 
D)  translation 
E)  replication 
A)  initiation 
B)  elongation 
C)  termination 
D)  translation 
E)  replication A,B,C

Question 2

What is the purpose of phosphorylating the carboxy terminal domain (CTD)of RNA Polymerase II?

Accepted Answer

A)  convert from the initiation to the elongation stage 
B)  to aid in transcriptional initiation 
C)  phosphorylate transcription factors 
D)  allow transcription factors to bind the TATA box 
A)  convert from the initiation to the elongation stage 
B)  to aid in transcriptional initiation 
C)  phosphorylate transcription factors 
D)  allow transcription factors to bind the TATA box A

Question 3

Which of the following forms of RNA encodes the sequence of amino acids for a functional protein?

Accepted Answer

A)  tRNA 
B)  snRNA 
C)  mRNA 
D)  rRNA 
E)  scRNA 
A)  tRNA 
B)  snRNA 
C)  mRNA 
D)  rRNA 
E)  scRNA C

Question 4

During translation,the mRNA is read in groups of nucleotides called quadrons.

Accepted Answer

A) True 
 B)False

Question 5

A functional eukaryotic protein is typically made up of the information contained within what region of pre-mRNA?

Accepted Answer

A)  exons 
B)  introns 
C)  enhancers 
D)  promoters 
A)  exons 
B)  introns 
C)  enhancers 
D)  promoters

Question 6

RNA polymerase I in eukaryotes produces which type of RNA?

Accepted Answer

A)  snRNA 
B)  tRNA 
C)  5S rRNA 
D)  18S rRNA 
A)  snRNA 
B)  tRNA 
C)  5S rRNA 
D)  18S rRNA

Question 7

The RNA polymerase forms a closed complex during the process of elongation during transcription.

Accepted Answer

A) True 
 B)False

Question 8

A ribozyme is a catalytic protein that assists in the processing of tRNA.

Accepted Answer

A) True 
 B)False

Question 9

What enables the splicing of group I and II introns?

Accepted Answer

A)  spliceosomes 
B)  ribozymes 
C)  snRNA 
D)  poly-A tail 
A)  spliceosomes 
B)  ribozymes 
C)  snRNA 
D)  poly-A tail

Question 10

Basal transcription in eukaryotes involves the action of only the core promoter.

Accepted Answer

A) True 
 B)False

Question 11

Select the components of the eukaryotic preinitiation complex.

Accepted Answer

A)  TFIID 
B)  DNA 
C)  TFIIB 
D)  RNA polymerase II 
E)  mediator 
A)  TFIID 
B)  DNA 
C)  TFIIB 
D)  RNA polymerase II 
E)  mediator

Question 12

In prokaryotes,a holoenzyme is formed when what is added to the core enzyme?

Accepted Answer

A)  Start codons 
B)  b 
C)  b' 
D)  σ 
E)  a 
A)  Start codons 
B)  b 
C)  b' 
D)  σ 
E)  a

Question 13

In trying to distinguish between the two models of eukaryotic transcriptional termination,you identify a drug that specifically blocks exonuclease activity.When you add it at the appropriate time to an in vitro system that carries out all the stages of eukaryotic transcription,you find that transcription proceeds normally,but transcription doesn't terminate. This experiment provides support for which model of eukaryotic transcriptional termination?

Accepted Answer

A)  Allosteric model 
B)  Torpedo model 
C)  Rho-dependent termination 
D)  Rho-independent termination 
A)  Allosteric model 
B)  Torpedo model 
C)  Rho-dependent termination 
D)  Rho-independent termination

Question 14

What region in eukaryotic genes contains the majority of regulatory elements?

Accepted Answer

A)  0 to 50 
B)  −50 to 0 
C)  −50 to −100 
D)  −100 to −150 
A)  0 to 50 
B)  −50 to 0 
C)  −50 to −100 
D)  −100 to −150

Question 15

The Prinbow box contains a CACAAC consensus sequence located in the −100 region of the promoter.

Accepted Answer

A) True 
 B)False

Question 16

A mutation in which of the following would result in a failure of the RNA polymerase to maintain an open complex?

Accepted Answer

A)  TFIIB 
B)  TFIID 
C)  TFIIE 
D)  TFIIH 
E)  TFIIF 
A)  TFIIB 
B)  TFIID 
C)  TFIIE 
D)  TFIIH 
E)  TFIIF

Question 17

The formation of open complex usually forms in GC-rich regions of DNA due to the decreased number of hydrogen bonds.

Accepted Answer

A) True 
 B)False

Question 18

Which of the following is not an example of a eukaryotic regulatory element?

Accepted Answer

A)  enhancers 
B)  silencers 
C)  core promoters 
D)  cis-acting elements 
E)  All of the answers are examples. 
A)  enhancers 
B)  silencers 
C)  core promoters 
D)  cis-acting elements 
E)  All of the answers are examples.

Question 19

Following transcription,the RNA has a complementary sequence to

Accepted Answer

A)  regulatory sequences. 
B)  termination sequences. 
C)  the coding strand of DNA. 
D)  the template strand of DNA. 
A)  regulatory sequences. 
B)  termination sequences. 
C)  the coding strand of DNA. 
D)  the template strand of DNA.

Question 20

Which subunit of the prokaryotic RNA polymerase carries out catalytic synthesis of RNA?

Accepted Answer

A)  alpha 
B)  omega 
C)  beta 
D)  sigma 
A)  alpha 
B)  omega 
C)  beta 
D)  sigma

Exam 14: Gene Transcription and RNA Modification

Select the stages of transcription.

What is the purpose of phosphorylating the carboxy terminal domain (CTD)of RNA Polymerase II?

Which of the following forms of RNA encodes the sequence of amino acids for a functional protein?

During translation,the mRNA is read in groups of nucleotides called quadrons.

A functional eukaryotic protein is typically made up of the information contained within what region of pre-mRNA?

RNA polymerase I in eukaryotes produces which type of RNA?

The RNA polymerase forms a closed complex during the process of elongation during transcription.

A ribozyme is a catalytic protein that assists in the processing of tRNA.

What enables the splicing of group I and II introns?

Basal transcription in eukaryotes involves the action of only the core promoter.

Select the components of the eukaryotic preinitiation complex.

In prokaryotes,a holoenzyme is formed when what is added to the core enzyme?

What region in eukaryotic genes contains the majority of regulatory elements?

The Prinbow box contains a CACAAC consensus sequence located in the −100 region of the promoter.

A mutation in which of the following would result in a failure of the RNA polymerase to maintain an open complex?

The formation of open complex usually forms in GC-rich regions of DNA due to the decreased number of hydrogen bonds.

Which of the following is not an example of a eukaryotic regulatory element?

Following transcription,the RNA has a complementary sequence to

Which subunit of the prokaryotic RNA polymerase carries out catalytic synthesis of RNA?

Overview of Genetics

Reproduction and Chromosome Transmission

Mendelian Inheritance

Sex Determination and Sex Chromosomes

Extensions of Mendelian Inheritance

Extranuclear Inheritance, Imprinting, and Maternal Effect

Genetic Linkage and Mapping in Eukaryotes

Variation in Chromosome Structure and Number

Genetics in Bacteria

Genetics of Viruses

Molecular Structure of DNA and RNA

Molecular Structure of Chromosomes and Transposition

Dna Replication and Recombination

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes

Non-Coding Rnas

Gene Mutation and DNA Repair

Molecular Technologies

Genomics

Medical Genetics and Cancer

Population Genetics

Quantitative Genetics

Filters