Question 1

_____ is the most abundant class of antibodies in serum.

Accepted Answer

The answer of _____ is the most abundant class of...

Question 2

The progeny cells of a B-cell clone are called

Accepted Answer

A) antibodies. 
B) sensitized T cells. 
C) activated macrophages. 
D) plasma cells. 
E) Bursa cells. 
A) antibodies. 
B) sensitized T cells. 
C) activated macrophages. 
D) plasma cells. 
E) Bursa cells.

Question 3

The major histocompatability complex is

Accepted Answer

A) a group of blood vessels that protects the nervous system. 
B) a set of genes that code for MHC cell receptors. 
C) also known as the complement system. 
D) located in the thymus gland. 
E) all of the choices are correct. 
A) a group of blood vessels that protects the nervous system. 
B) a set of genes that code for MHC cell receptors. 
C) also known as the complement system. 
D) located in the thymus gland. 
E) all of the choices are correct.

Question 4

Which is incorrect about the Fc region of an immunoglobulin?

Accepted Answer

A) It determines the antibody's distribution in the body. 
B) It forms the antigen binding sites. 
C) It contains an effector molecule that can bind to cells such as macrophages and mast cells. 
D) It contains an effector molecule that can fix complement. 
E) It determines the class to which the immunoglobulin belongs. 
A) It determines the antibody's distribution in the body. 
B) It forms the antigen binding sites. 
C) It contains an effector molecule that can bind to cells such as macrophages and mast cells. 
D) It contains an effector molecule that can fix complement. 
E) It determines the class to which the immunoglobulin belongs.

Question 5

Each genetically distinct group of lymphocytes that possesses the same specificity is called a _____.

Accepted Answer

The answer of Each genetically distinct group of lymphocytes that...

Question 6

Discuss, in detail, all the genetic and cellular events encompassed in the clonal selection theory of lymphocyte development.

Accepted Answer

The clonal selection theory of lymphocyt

Question 7

In the primary response to an antigen, the first class of antibody to be secreted is

Accepted Answer

A) IgD. 
B) IgE. 
C) IgG. 
D) IgM. 
E) IgA. 
A) IgD. 
B) IgE. 
C) IgG. 
D) IgM. 
E) IgA.

Question 8

Each _____ fragment of an antibody molecule contains the variable regions of a heavy and light chain that folds into a groove for one antigenic determinant.

Accepted Answer

The answer of Each _____ fragment of an antibody molecule...

Question 9

Which of the immunizations would carry the greatest risk for immunocompromised patients?

Accepted Answer

A) Killed, inactivated vaccines 
B) Attenuated vaccines 
C) Toxoids 
D) Immune serums 
E) Subunit vaccines 
A) Killed, inactivated vaccines 
B) Attenuated vaccines 
C) Toxoids 
D) Immune serums 
E) Subunit vaccines

Question 10

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

Accepted Answer

A) Neutralization 
B) Opsonization 
C) Complement fixation 
D) Agglutination 
E) Anamnestic response 
A) Neutralization 
B) Opsonization 
C) Complement fixation 
D) Agglutination 
E) Anamnestic response

Question 11

The immunoglobulin class that is the only one capable of crossing the placenta is

Accepted Answer

A) IgA. 
B) IgD. 
C) IgE. 
D) IgG. 
E) IgM. 
A) IgA. 
B) IgD. 
C) IgE. 
D) IgG. 
E) IgM.

Question 12

Cytotoxic T cells

Accepted Answer

A) stimulate B cell proliferation. 
B) lack specificity for a target cell. 
C) secrete granzymes and perforins that damage target cells. 
D) secrete interleukin-2 to stimulate B and T cells. 
E) All of the choices are correct. 
A) stimulate B cell proliferation. 
B) lack specificity for a target cell. 
C) secrete granzymes and perforins that damage target cells. 
D) secrete interleukin-2 to stimulate B and T cells. 
E) All of the choices are correct.

Question 13

Which of the following is a special binding substance that enhances immugenicity and prolongs antigen retention at the injection site?

Accepted Answer

A) Adjuvant 
B) Booster 
C) Antibodies to toxin 
D) Gamma globulin 
E) "Trojan horse" recombinant vaccine 
A) Adjuvant 
B) Booster 
C) Antibodies to toxin 
D) Gamma globulin 
E) "Trojan horse" recombinant vaccine

Question 14

When antiserum is subjected to electrophoresis, the gamma globulin band contains mostly

Accepted Answer

A) IgM. 
B) IgA. 
C) IgD. 
D) IgE. 
E) IgG. 
A) IgM. 
B) IgA. 
C) IgD. 
D) IgE. 
E) IgG.

Question 15

Which antibody confers the most important specific local immunity to enteric, respiratory, and genitourinary pathogens?

Accepted Answer

A) IgD 
B) IgE 
C) IgG 
D) IgM 
E) IgA 
A) IgD 
B) IgE 
C) IgG 
D) IgM 
E) IgA

Question 16

Antitoxins

Accepted Answer

A) contain antibodies to neutralize specific toxin. 
B) use Vaccinia virus with genetic material of bacterial toxins. 
C) contain purified, chemically denatured bacterial exotoxin. 
D) include capsule material against the pneumococcus and meningococcus. 
E) contain attenuated organisms. 
A) contain antibodies to neutralize specific toxin. 
B) use Vaccinia virus with genetic material of bacterial toxins. 
C) contain purified, chemically denatured bacterial exotoxin. 
D) include capsule material against the pneumococcus and meningococcus. 
E) contain attenuated organisms.

Question 17

The immunoglobulin class that has a dimer form found in mucus, saliva, colostrum, and other body secretions is

Accepted Answer

A) IgA. 
B) IgD. 
C) IgE. 
D) IgG. 
E) IgM. 
A) IgA. 
B) IgD. 
C) IgE. 
D) IgG. 
E) IgM.

Question 18

Toxoids

Accepted Answer

A) contain modified bacterial exotoxin molecules. 
B) are always genetically engineered. 
C) contain select antigenic components of a pathogen rather than whole cells or viruses. 
D) confer passive immunity. 
E) All of the choices are correct. 
A) contain modified bacterial exotoxin molecules. 
B) are always genetically engineered. 
C) contain select antigenic components of a pathogen rather than whole cells or viruses. 
D) confer passive immunity. 
E) All of the choices are correct.

Question 19

The DTaP immunization

Accepted Answer

A) contains diphtheria toxoid. 
B) is administered in childhood. 
C) contains tetanus toxoid. 
D) contains a pertussis vaccine with acellular capsule material. 
E) All of the choices are correct. 
A) contains diphtheria toxoid. 
B) is administered in childhood. 
C) contains tetanus toxoid. 
D) contains a pertussis vaccine with acellular capsule material. 
E) All of the choices are correct.

Question 20

All of the following are advantages of attenuated vaccines over inactivated vaccines except

Accepted Answer

A) they confer longer lasting protection. 
B) they produce infection but not disease. 
C) they can mutate back to a virulent strain. 
D) they require fewer boosters. 
E) they require smaller doses. 
A) they confer longer lasting protection. 
B) they produce infection but not disease. 
C) they can mutate back to a virulent strain. 
D) they require fewer boosters. 
E) they require smaller doses.

Exam 15: Adaptive, Specific Immunity and Immunization

_____ is the most abundant class of antibodies in serum.

The progeny cells of a B-cell clone are called

The major histocompatability complex is

Which is incorrect about the Fc region of an immunoglobulin?

Each genetically distinct group of lymphocytes that possesses the same specificity is called a _____.

Discuss, in detail, all the genetic and cellular events encompassed in the clonal selection theory of lymphocyte development.

In the primary response to an antigen, the first class of antibody to be secreted is

Each _____ fragment of an antibody molecule contains the variable regions of a heavy and light chain that folds into a groove for one antigenic determinant.

Which of the immunizations would carry the greatest risk for immunocompromised patients?

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

The immunoglobulin class that is the only one capable of crossing the placenta is

Cytotoxic T cells

Which of the following is a special binding substance that enhances immugenicity and prolongs antigen retention at the injection site?

When antiserum is subjected to electrophoresis, the gamma globulin band contains mostly

Which antibody confers the most important specific local immunity to enteric, respiratory, and genitourinary pathogens?

Antitoxins

The immunoglobulin class that has a dimer form found in mucus, saliva, colostrum, and other body secretions is

Toxoids

The DTaP immunization

All of the following are advantages of attenuated vaccines over inactivated vaccines except

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