Question 1

The process of clonal deletion is designed to

Accepted Answer

A) destroy clones of lymphocytes able to react to self molecules. 
B) slow down the primary immune response to an antigen. 
C) slow down the secondary immune response to an antigen. 
D) limit the number of lymphocyte clones an individual has in order to make the system more efficient. 
E) slow down the immune system in the elderly. 
A) destroy clones of lymphocytes able to react to self molecules. 
B) slow down the primary immune response to an antigen. 
C) slow down the secondary immune response to an antigen. 
D) limit the number of lymphocyte clones an individual has in order to make the system more efficient. 
E) slow down the immune system in the elderly.

Question 2

Herceptin is an example of a monoclonal antibody-based drug for

Accepted Answer

A) asthma. 
B) Chron's disease. 
C) breast cancer. 
D) respiratory syncytial virus. 
E) All of the choices are correct. 
A) asthma. 
B) Chron's disease. 
C) breast cancer. 
D) respiratory syncytial virus. 
E) All of the choices are correct.

Question 3

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is

Accepted Answer

A) IgA. 
B) IgD. 
C) IgE. 
D) IgG 
E) IgM. 
A) IgA. 
B) IgD. 
C) IgE. 
D) IgG 
E) IgM.

Question 4

Describe the major histocompatability complex with regard to its: a) location, b) composition, c) relationship to specific cell markers, and d) role in regulation of immune reactions.

Accepted Answer

The major histocompatibility complex (MH

Question 5

Autoantigens are types of self-antigens that initiate an autoimmune response that can cause damage to host tissue.

Accepted Answer

A) True 
 B)False

Question 6

An example of artificial active immunity would be

Accepted Answer

A) chickenpox infection is followed by lifelong immunity. 
B) chickenpox vaccine triggers extended immunity to chickenpox. 
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta. 
E) None of the choices are correct. 
A) chickenpox infection is followed by lifelong immunity. 
B) chickenpox vaccine triggers extended immunity to chickenpox. 
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta. 
E) None of the choices are correct.

Question 7

Which cells' direct involvement are required for cell-mediated immunity?

Accepted Answer

A) T-cells 
B) B-cells 
C) Bacterial cells 
D) Viral components 
E) Neutrophils 
A) T-cells 
B) B-cells 
C) Bacterial cells 
D) Viral components 
E) Neutrophils

Question 8

Which kind of T cell synthesizes perforins and granzymes to destroy bacteria, viral infected cells, and cancer cells?

Accepted Answer

A) TC 
B) TH 
C) CD4 
D) MHC 
A) TC 
B) TH 
C) CD4 
D) MHC

Question 9

Lymphocytes:

Accepted Answer

A) possess MHC antigens for recognizing self. 
B) have membrane receptors that recognize foreign antigens. 
C) gain tolerance to self by destruction of lymphocytes that could react against self. 
D) develop into clones of B and T cells with extreme variations of specificity. 
E) all of the choices are correct. 
A) possess MHC antigens for recognizing self. 
B) have membrane receptors that recognize foreign antigens. 
C) gain tolerance to self by destruction of lymphocytes that could react against self. 
D) develop into clones of B and T cells with extreme variations of specificity. 
E) all of the choices are correct.

Question 10

An example of artificial passive immunity would be

Accepted Answer

A) chickenpox infection is followed by lifelong immunity. 
B) chickenpox vaccine triggers extended immunity to chickenpox. 
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta. 
E) None of the choices are correct. 
A) chickenpox infection is followed by lifelong immunity. 
B) chickenpox vaccine triggers extended immunity to chickenpox. 
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta. 
E) None of the choices are correct.

Question 11

Edward Jenner's work involved

Accepted Answer

A) inoculation of dried pus from smallpox pustules into a person to stimulate immunity. 
B) development of passive immunotherapy. 
C) development of an immunization to protect people against cowpox. 
D) immunization using a related, less pathogenic organism to give protection against a more pathogenic one. 
E) All of the choices are correct. 
A) inoculation of dried pus from smallpox pustules into a person to stimulate immunity. 
B) development of passive immunotherapy. 
C) development of an immunization to protect people against cowpox. 
D) immunization using a related, less pathogenic organism to give protection against a more pathogenic one. 
E) All of the choices are correct.

Question 12

The albumin fraction of serum separated by electrophoresis will contain most of the antibodies.

Accepted Answer

A) True 
 B)False

Question 13

Cody is 4 months old and is given a DTaP injection by his pediatrician as part of the routine immunization schedule.What type of immunity will develop as a result of this?

Accepted Answer

A) Natural active immunity 
B) Artificial passive immunity 
C) Natural passive immunity 
D) Artificial active immunity 
E) None of the choices will protect him. 
A) Natural active immunity 
B) Artificial passive immunity 
C) Natural passive immunity 
D) Artificial active immunity 
E) None of the choices will protect him.

Question 14

The monomer subunit of immunoglobulin molecules has all the following, except

Accepted Answer

A) two identical heavy polypeptide chains. 
B) two identical light polypeptide chains. 
C) disulfide bonds between polypeptide chains. 
D) four antigen binding sites. 
E) a variable and constant region on each polypeptide chain. 
A) two identical heavy polypeptide chains. 
B) two identical light polypeptide chains. 
C) disulfide bonds between polypeptide chains. 
D) four antigen binding sites. 
E) a variable and constant region on each polypeptide chain.

Question 15

All of the following are characteristics of IgM, except

Accepted Answer

A) it has 10 antigen binding sites. 
B) it contains a central J chain. 
C) it is the first class synthesized by a plasma cell. 
D) it can fix complement. 
E) it is a dimer. 
A) it has 10 antigen binding sites. 
B) it contains a central J chain. 
C) it is the first class synthesized by a plasma cell. 
D) it can fix complement. 
E) it is a dimer.

Question 16

Which are the first to attack cancer cells and virus-infected cells?

Accepted Answer

A) helper T cells 
B) suppressor T cells 
C) cytotoxic T cells 
D) delayed hypersensitivity T cells 
E) natural killer (NK) cells 
A) helper T cells 
B) suppressor T cells 
C) cytotoxic T cells 
D) delayed hypersensitivity T cells 
E) natural killer (NK) cells

Question 17

The bone marrow is where

Accepted Answer

A) immune responses to antigen occur. 
B) blood stem cells give rise to immature lymphocytes. 
C) antigen is filtered from the blood. 
D) antigen is filtered from tissue fluid. 
E) T lymphocytes complete maturation. 
A) immune responses to antigen occur. 
B) blood stem cells give rise to immature lymphocytes. 
C) antigen is filtered from the blood. 
D) antigen is filtered from tissue fluid. 
E) T lymphocytes complete maturation.

Question 18

Class II MHC genes code for

Accepted Answer

A) certain secreted complement components. 
B) self receptors recognized by natural killer cells. 
C) all HLA antigens. 
D) receptors located primarily on macrophages, dendritic cells, and B cells. 
E) all of the choices are correct. 
A) certain secreted complement components. 
B) self receptors recognized by natural killer cells. 
C) all HLA antigens. 
D) receptors located primarily on macrophages, dendritic cells, and B cells. 
E) all of the choices are correct.

Question 19

Antigen presenting cells

Accepted Answer

A) include dendritic cells. 
B) include macrophages. 
C) engulf and modify antigen to be more immunogenic. 
D) hold and present processed antigen on their cell membrane surface. 
E) All of the choices are correct. 
A) include dendritic cells. 
B) include macrophages. 
C) engulf and modify antigen to be more immunogenic. 
D) hold and present processed antigen on their cell membrane surface. 
E) All of the choices are correct.

Question 20

Class I MHC genes code for

Accepted Answer

A) certain secreted complement components. 
B) markers that display unique characteristics of self. 
C) all HLA antigens. 
D) receptors located primarily on macrophages and B cells. 
E) all of the choices are correct. 
A) certain secreted complement components. 
B) markers that display unique characteristics of self. 
C) all HLA antigens. 
D) receptors located primarily on macrophages and B cells. 
E) all of the choices are correct.

Exam 15: Adaptive, Specific Immunity and Immunization

The process of clonal deletion is designed to

Herceptin is an example of a monoclonal antibody-based drug for

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is

Describe the major histocompatability complex with regard to its: a) location, b) composition, c) relationship to specific cell markers, and d) role in regulation of immune reactions.

Autoantigens are types of self-antigens that initiate an autoimmune response that can cause damage to host tissue.

An example of artificial active immunity would be

Which cells' direct involvement are required for cell-mediated immunity?

Which kind of T cell synthesizes perforins and granzymes to destroy bacteria, viral infected cells, and cancer cells?

Lymphocytes:

An example of artificial passive immunity would be

Edward Jenner's work involved

The albumin fraction of serum separated by electrophoresis will contain most of the antibodies.

Cody is 4 months old and is given a DTaP injection by his pediatrician as part of the routine immunization schedule.What type of immunity will develop as a result of this?

The monomer subunit of immunoglobulin molecules has all the following, except

All of the following are characteristics of IgM, except

Which are the first to attack cancer cells and virus-infected cells?

The bone marrow is where

Class II MHC genes code for

Antigen presenting cells

Class I MHC genes code for

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