Question 1

T cell response to T-cell-dependent antigens requires

Accepted Answer

A) typically a protein antigen. 
B) binding of T cell to a Class II MHC receptor on an antigen-presenting cell. 
C) binding of T cell to a site on the antigen. 
D) interleukin-1 activating the T helper cell. 
E) All of the choices are correct. 
A) typically a protein antigen. 
B) binding of T cell to a Class II MHC receptor on an antigen-presenting cell. 
C) binding of T cell to a site on the antigen. 
D) interleukin-1 activating the T helper cell. 
E) All of the choices are correct.

Question 2

Variolation involved using

Accepted Answer

A) dried, ground smallpox scabs. 
B) a recombinant carrier with genetic material of the smallpox virus. 
C) preparations of human cowpox lesions. 
D) antibodies to the smallpox virus. 
E) None of the choices are correct. 
A) dried, ground smallpox scabs. 
B) a recombinant carrier with genetic material of the smallpox virus. 
C) preparations of human cowpox lesions. 
D) antibodies to the smallpox virus. 
E) None of the choices are correct.

Question 3

Killed or inactivated vaccines are prepared by

Accepted Answer

A) removal of virulence genes from the microbe. 
B) treatment with formalin, heat, or radiation. 
C) passage of the pathogen through unnatural hosts or tissue culture. 
D) long-term subculturing of the microbe. 
E) All of the choices are correct. 
A) removal of virulence genes from the microbe. 
B) treatment with formalin, heat, or radiation. 
C) passage of the pathogen through unnatural hosts or tissue culture. 
D) long-term subculturing of the microbe. 
E) All of the choices are correct.

Question 4

Vaccinia virus is often used in the technique to make

Accepted Answer

A) Adjuvant. 
B) Booster. 
C) Antibodies to toxin. 
D) Gamma globulin. 
E) "Trojan horse" recombinant vaccine. 
A) Adjuvant. 
B) Booster. 
C) Antibodies to toxin. 
D) Gamma globulin. 
E) "Trojan horse" recombinant vaccine.

Question 5

Which process involves a more rapid synthesis and greatly increased titer of antibody when the immune system is subsequently exposed to the same antigen?

Accepted Answer

A) Neutralization 
B) Opsonization 
C) Complement fixation 
D) Agglutination 
E) Anamnestic response 
A) Neutralization 
B) Opsonization 
C) Complement fixation 
D) Agglutination 
E) Anamnestic response

Question 6

Which sequence of events is correct for a specific immune response?

Accepted Answer

A) Lymphocyte development, presentation of antigens, antibody production, challenge of B cells. 
B) Lymphocyte development, challenge of B cells, antibody production, presentation of antigens. 
C) Lymphocyte development, presentation of antigens, B cell challenge, antibody production. 
D) Antibody production, lymphocyte production, B cell challenge, presentation of antigens. 
E) Presentation of antigens, B cell challenge, antibody production, lymphocyte development. 
A) Lymphocyte development, presentation of antigens, antibody production, challenge of B cells. 
B) Lymphocyte development, challenge of B cells, antibody production, presentation of antigens. 
C) Lymphocyte development, presentation of antigens, B cell challenge, antibody production. 
D) Antibody production, lymphocyte production, B cell challenge, presentation of antigens. 
E) Presentation of antigens, B cell challenge, antibody production, lymphocyte development.

Question 7

Human B lymphocytes mature in an intestinal region called the bursa.

Accepted Answer

A) True 
 B)False

Question 8

Immunotherapy is the

Accepted Answer

A) use of antitoxins. 
B) use of immune serum globulin. 
C) conferring of passive immunity. 
D) administering of preformed antibodies. 
E) All of the choices are correct. 
A) use of antitoxins. 
B) use of immune serum globulin. 
C) conferring of passive immunity. 
D) administering of preformed antibodies. 
E) All of the choices are correct.

Question 9

Monoclonal antibodies

Accepted Answer

A) originate from a single B cell clone. 
B) have a single specificity for antigen. 
C) are secreted by hybridomas. 
D) are used in immunology lab tests and cancer therapy. 
E) All of the choices are correct. 
A) originate from a single B cell clone. 
B) have a single specificity for antigen. 
C) are secreted by hybridomas. 
D) are used in immunology lab tests and cancer therapy. 
E) All of the choices are correct.

Question 10

Antibody molecules circulate in lymph, blood, and tissue fluids.

Accepted Answer

A) True 
 B)False

Question 11

Activation of B cells occurs when antigen bonds to B cell surface immunoglobulin receptors.

Accepted Answer

A) True 
 B)False

Question 12

The region of each antibody molecule where amino acid composition is very different from one clone of B lymphocytes to another is the

Accepted Answer

A) variable region. 
B) joining region. 
C) constant region. 
D) light region. 
E) hinge region. 
A) variable region. 
B) joining region. 
C) constant region. 
D) light region. 
E) hinge region.

Question 13

Lymphocyte maturation involves

Accepted Answer

A) hormonal signals that initiate development. 
B) B cells maturing in bone marrow sites. 
C) T cells maturing in the thymus. 
D) release of mature lymphocytes to begin migration to various lymphoid organs. 
E) all of the choices are correct. 
A) hormonal signals that initiate development. 
B) B cells maturing in bone marrow sites. 
C) T cells maturing in the thymus. 
D) release of mature lymphocytes to begin migration to various lymphoid organs. 
E) all of the choices are correct.

Question 14

Live, attenuated vaccines

Accepted Answer

A) include the Sabin polio vaccine. 
B) include the measles, mumps, rubella vaccine (MMR). 
C) contain viable microbes that can multiply in the person. 
D) require smaller doses and fewer boosters compared to inactivated vaccines. 
E) All of the choices are correct. 
A) include the Sabin polio vaccine. 
B) include the measles, mumps, rubella vaccine (MMR). 
C) contain viable microbes that can multiply in the person. 
D) require smaller doses and fewer boosters compared to inactivated vaccines. 
E) All of the choices are correct.

Question 15

Immune sera is produced in horses for all the following except

Accepted Answer

A) diphtheria. 
B) botulism. 
C) snake bites. 
D) chickenpox. 
E) spider bites. 
A) diphtheria. 
B) botulism. 
C) snake bites. 
D) chickenpox. 
E) spider bites.

Question 16

The immunoglobulin/s found on the surface of B cells is/are

Accepted Answer

A) IgM only. 
B) IgG only. 
C) IgD only. 
D) IgM and IgG. 
E) IgE and IgA. 
A) IgM only. 
B) IgG only. 
C) IgD only. 
D) IgM and IgG. 
E) IgE and IgA.

Question 17

All of the following are advantages of attenuated vaccines over inactivated vaccines except

Accepted Answer

A) they require smaller doses. 
B) they require fewer boosters. 
C) they confer longer lasting protection. 
D) they can be transmitted to other people. 
E) they produce infection but not disease. 
A) they require smaller doses. 
B) they require fewer boosters. 
C) they confer longer lasting protection. 
D) they can be transmitted to other people. 
E) they produce infection but not disease.

Question 18

High titers of specific antibodies are components of

Accepted Answer

A) specific immune globulin (SIG). 
B) gamma globulin. 
C) immune serum globulin (ISG). 
D) attenuated vaccines. 
E) toxoids. 
A) specific immune globulin (SIG). 
B) gamma globulin. 
C) immune serum globulin (ISG). 
D) attenuated vaccines. 
E) toxoids.

Question 19

The differences in the classes of immunoglobulins are due primarily to variations in the Fc fragment.

Accepted Answer

A) True 
 B)False

Question 20

Antigens that elicit allergic reactions are called _____.

Accepted Answer

The answer of Antigens that elicit allergic reactions are called...

Exam 15: Adaptive, Specific Immunity and Immunization

T cell response to T-cell-dependent antigens requires

Variolation involved using

Killed or inactivated vaccines are prepared by

Vaccinia virus is often used in the technique to make

Which process involves a more rapid synthesis and greatly increased titer of antibody when the immune system is subsequently exposed to the same antigen?

Which sequence of events is correct for a specific immune response?

Human B lymphocytes mature in an intestinal region called the bursa.

Immunotherapy is the

Monoclonal antibodies

Antibody molecules circulate in lymph, blood, and tissue fluids.

Activation of B cells occurs when antigen bonds to B cell surface immunoglobulin receptors.

The region of each antibody molecule where amino acid composition is very different from one clone of B lymphocytes to another is the

Lymphocyte maturation involves

Live, attenuated vaccines

Immune sera is produced in horses for all the following except

The immunoglobulin/s found on the surface of B cells is/are

All of the following are advantages of attenuated vaccines over inactivated vaccines except

High titers of specific antibodies are components of

The differences in the classes of immunoglobulins are due primarily to variations in the Fc fragment.

Antigens that elicit allergic reactions are called _____.

The Main Themes of Microbiology

The Chemistry of Biology

Tools of the Laboratory: Methods of Studying Microorganisms

A Survey of Prokaryotic Cells and Microorganisms

A Survey of Eukaryotic Cells and Microorganisms

An Introduction to Viruses

Microbial Nutrition, Ecology, and Growth

An Introduction to Microbial Metabolism: the Chemical Crossroads of Life

An Introduction to Microbial Genetics

Genetic Engineering: a Revolution in Molecular Biology

Physical and Chemical Agents for Microbial Control

Drugs, Microbes, Host-The Elements of Chemotherapy

Microbe-Human Interactions: Infection, Disease, and Epidemiology

An Introduction to Host Defenses and Innate Immunities

Disorders in Immunity

Procedures for Identifying Pathogens and Diagnosing Infections

The Gram-Positive and Gram-Negative Cocci of Medical Importance

The Gram-Positive Bacilli of Medical Importance

The Gram-Negative Bacilli of Medical Importance

Miscellaneous Bacterial Agents of Disease

The Fungi of Medical Importance

The Parasites of Medical Importance

Introduction to Viruses That Infect Humans: the Dna Viruses

The Rna Viruses That Infect Humans

Environmental Microbiology

Applied and Industrial Microbiology

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