A) is frequently associated with alterations in serum proteins. B) occurs when serum viscosity is increased. C) can be confused with pan-agglutination. D) all of the above. A) is frequently associated with alterations in serum proteins. B) occurs when serum viscosity is increased. C) can be confused with pan-agglutination. D) all of the above.

Exam 9: Detection and Identification of Antibodies

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While performing an antibody screen, a test reaction is observed that is suspected to be rouleaux. A saline replacement test is done, and the reaction remains. What is the best interpretation?

(Multiple Choice)

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Question 61

A patient with a warm autoantibody has a positive DAT. The antibody screen was negative, but the eluate reacted uniformly with all normal cells and patient cells. Why was the antibody screen negative?

(Multiple Choice)

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Question 62

What is the purpose of Coombs' control cells?

(Multiple Choice)

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Question 63

What would be a realistic source of finding compatible units for a person with an antibody to a high-frequency antigen?

(Multiple Choice)

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Question 64

When performing the elution procedure, the solution containing the recovered antibody is called:

(Multiple Choice)

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Question 65

One drop of Coombs' control cells was added to a negative antibody screen. No agglutination was observed after centrifugation. What course of action is taken?

(Multiple Choice)

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Question 66

Of the antibodies listed below, which does NOT fit with the others in terms of the optimal temperature of reactivity?

(Multiple Choice)

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Question 67

How many units would you likely have to screen to find two compatible units for someone with the following antibodies: anti-C, anti-Le^a, anti-Jk^b?

(Multiple Choice)

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Question 68

What is the simplest way of reducing the interferences from benign cold autoantibodies in antibody screening procedures?

(Multiple Choice)

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Question 69

A doctor has ordered 4 units of red blood cells for a patient with anti-E in his serum. How many units would have to be screened to yield 4 E-negative units?

(Multiple Choice)

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Question 70

Why is it important for screening cells to be from individuals who have a homozygous expression of antigens?

(Multiple Choice)

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Question 71

A person has developed an antibody to the LISS reagent. What test will not be affected by this circumstance?

(Multiple Choice)

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Question 72

Pseudoagglutination:

(Multiple Choice)

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Question 73

A 2-unit crossmatch was ordered on a patient in the emergency room. The patient's antibody screen was negative. One unit was compatible and the other was incompatible at AHG. If the patient's antibody screen was negative and the donor had no history of antibodies, what could be the reason for this reaction?

(Multiple Choice)

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Question 74

In what circumstance would an alloadsorption be performed?

(Multiple Choice)

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Question 75

Cells that have antibody attached to them but are still separated from one another are:

(Multiple Choice)

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Question 76

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Exam 9: Detection and Identification of Antibodies

While performing an antibody screen, a test reaction is observed that is suspected to be rouleaux. A saline replacement test is done, and the reaction remains. What is the best interpretation?

A patient with a warm autoantibody has a positive DAT. The antibody screen was negative, but the eluate reacted uniformly with all normal cells and patient cells. Why was the antibody screen negative?

What is the purpose of Coombs' control cells?

What would be a realistic source of finding compatible units for a person with an antibody to a high-frequency antigen?

When performing the elution procedure, the solution containing the recovered antibody is called:

One drop of Coombs' control cells was added to a negative antibody screen. No agglutination was observed after centrifugation. What course of action is taken?

Of the antibodies listed below, which does NOT fit with the others in terms of the optimal temperature of reactivity?

How many units would you likely have to screen to find two compatible units for someone with the following antibodies: anti-C, anti-Lea, anti-Jkb?

What is the simplest way of reducing the interferences from benign cold autoantibodies in antibody screening procedures?

A doctor has ordered 4 units of red blood cells for a patient with anti-E in his serum. How many units would have to be screened to yield 4 E-negative units?

Why is it important for screening cells to be from individuals who have a homozygous expression of antigens?

A person has developed an antibody to the LISS reagent. What test will not be affected by this circumstance?

Pseudoagglutination:

In what circumstance would an alloadsorption be performed?

Cells that have antibody attached to them but are still separated from one another are:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

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How many units would you likely have to screen to find two compatible units for someone with the following antibodies: anti-C, anti-Le^a, anti-Jk^b?