Question 1

All of the following are characteristics of monoclonal reagents except:

Accepted Answer

A)  an absence of batch variation. 
B)  antibodies directed against a single epitope. 
C)  undetectable subgroups of A. 
D)  monoclonal antibodies with high affinities. 
A)  an absence of batch variation. 
B)  antibodies directed against a single epitope. 
C)  undetectable subgroups of A. 
D)  monoclonal antibodies with high affinities.

Question 2

What test is used to remove autoantibodies from test serum?

Accepted Answer

A)  Adsorption 
B)  Direct Coombs' 
C)  Elution 
D)  Indirect Coombs' 
A)  Adsorption 
B)  Direct Coombs' 
C)  Elution 
D)  Indirect Coombs'

Question 3

Which immunoglobulin exists in a pentameric configuration?

Accepted Answer

A)  IgG 
B)  IgM 
C)  IgA 
D)  IgE 
A)  IgG 
B)  IgM 
C)  IgA 
D)  IgE

Question 4

HLA proteins are coded by what complex?

Accepted Answer

A)  Major histocompatibility complex 
B)  Human leukocyte compatibility complex 
C)  Complement 
D)  Innate immune response 
A)  Major histocompatibility complex 
B)  Human leukocyte compatibility complex 
C)  Complement 
D)  Innate immune response

Question 5

A patient with multiple myeloma exhibits rouleaux formation in an immediate spin crossmatch. What procedure is recommended to distinguish true red blood cell agglutination from nonspecific agglutination?

Accepted Answer

A)  Secretor studies 
B)  Saline dilution 
C)  Enzyme treatment 
D)  Polyethylene glycol enhancement 
A)  Secretor studies 
B)  Saline dilution 
C)  Enzyme treatment 
D)  Polyethylene glycol enhancement

Question 6

What is the equivalent of Factor D (alternative pathway) in the classic complement pathway?

Accepted Answer

A)  C1q 
B)  C1s 
C)  C1r 
D)  C4 
A)  C1q 
B)  C1s 
C)  C1r 
D)  C4

Question 7

Why is low ionic strength solution (LISS) used in blood banking?

Accepted Answer

A)  It reduces the incubation time. 
B)  It reduces the net negative surface charge on the RBC. 
C)  It increases the zeta potential. 
D)  It enhances aggregation. 
A)  It reduces the incubation time. 
B)  It reduces the net negative surface charge on the RBC. 
C)  It increases the zeta potential. 
D)  It enhances aggregation.

Question 8

Which immunoglobulin is found in greatest concentration in serum?

Accepted Answer

A)  IgE 
B)  IgM 
C)  IgG 
D)  IgA 
A)  IgE 
B)  IgM 
C)  IgG 
D)  IgA

All of the following are characteristics of monoclonal reagents except:

What test is used to remove autoantibodies from test serum?

Which immunoglobulin exists in a pentameric configuration?

HLA proteins are coded by what complex?

A patient with multiple myeloma exhibits rouleaux formation in an immediate spin crossmatch. What procedure is recommended to distinguish true red blood cell agglutination from nonspecific agglutination?

What is the equivalent of Factor D (alternative pathway) in the classic complement pathway?

Why is low ionic strength solution (LISS) used in blood banking?

Which immunoglobulin is found in greatest concentration in serum?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

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Exam 3: Fundamentals of Immunology

All of the following are characteristics of monoclonal reagents except:

What test is used to remove autoantibodies from test serum?

Which immunoglobulin exists in a pentameric configuration?

HLA proteins are coded by what complex?

A patient with multiple myeloma exhibits rouleaux formation in an immediate spin crossmatch. What procedure is recommended to distinguish true red blood cell agglutination from nonspecific agglutination?

What is the equivalent of Factor D (alternative pathway) in the classic complement pathway?

Why is low ionic strength solution (LISS) used in blood banking?

Which immunoglobulin is found in greatest concentration in serum?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The RH Blood Group System

Blood Group Terminology and the Other Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Overview of the Routine Blood Bank Laboratory

Other Technologies and Automation

Donor Screening and Component Preparation

Apheresis

Transfusion Therapy

Cellular Therapy

Transfusion-Transmitted Diseases

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Transfusion Safety and Federal Regulatory Requirements

Utilization Management

Laboratory Information Systems

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Tissue Banking: A New Role for the Transfusion Service

Filters