Exam 8: Evolution in Finite Populations

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How are the neutral theory of molecular evolution and the Hardy-Weinberg equilibrium similar?

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Both are used as null models in evolutionary biology.

The effective population size is often lower than the census size of a population because

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D

Consider a collection of 50 distinct alleles, each at equal frequency in a population. The time before the first coalescent event will be shortest if

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A researcher examines a microsatellite locus in a wild population of D. melanogaster. She finds that in a sample of 50 individuals, 20 different alleles are segregating. According to the neutral theory, these alleles are most likely experiencing

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The neutral theory predicts a constant rate of substitutions per generation; however, molecular clock estimates show that substitutions accumulate annually regardless of the generation time. What explanation for this discrepancy is illustrated in the figure? The neutral theory predicts a constant rate of substitutions per generation; however, molecular clock estimates show that substitutions accumulate annually regardless of the generation time. What explanation for this discrepancy is illustrated in the figure?

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Population bottlenecks occur when

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Consider a population with an effective size of 4,000 and 32 segregating alleles. On average, how many generations would it take for all 32 alleles to coalesce to a single, ancestral allele?

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A founder event changes allele frequencies because

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Consider a population of lizards living on the coast of Africa. A storm creates piles of debris that the lizards use to raft to a faraway uninhabited island. Which evolutionary process is happening?

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Consider a series of island populations each founded by a single individual that is heterozygous at a particular locus. If the alleles at this locus are neutral, and there is no mutation or migration, describe what the variation will look like after many generations within each population and between populations. Why?

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A rancher genotypes all of her 150 head of cattle. In her herd, 25 are A1A1, 75 are A1A2, and 50 are A2A2. Assuming there is random mating, no selection, no mutation, and no new cattle are introduced into the population, what is the probability that the A1 allele will be fixed?

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In the figure, assuming all evolutionary processes are similar in A-D, which genealogy is expected to carry the largest number of neutral alleles? In the figure, assuming all evolutionary processes are similar in A-D, which genealogy is expected to carry the largest number of neutral alleles?

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Why might a wind-pollinated plant experience different levels of diversity in mitochondrial versus nuclear loci following a postglacial recolonization event?

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The graphs show the results of simulations of changes in the frequency of a neutral allele. Each graph shows 10 different runs of the simulation. What is the most likely difference between these simulations? Explain your reasoning. A The graphs show the results of simulations of changes in the frequency of a neutral allele. Each graph shows 10 different runs of the simulation. What is the most likely difference between these simulations? Explain your reasoning. A    B    C  B The graphs show the results of simulations of changes in the frequency of a neutral allele. Each graph shows 10 different runs of the simulation. What is the most likely difference between these simulations? Explain your reasoning. A    B    C  C The graphs show the results of simulations of changes in the frequency of a neutral allele. Each graph shows 10 different runs of the simulation. What is the most likely difference between these simulations? Explain your reasoning. A    B    C

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Explain why the probability of fixation of a new beneficial allele is independent of population size in Haldane's model of selection and drift.

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Consider two species, 1 and 2, that experience different mutation rates with m1 < m2, and have populations sizes of Ne1 < Ne2. Which species would you expect to have a lower frequency of heterozygotes at a neutral locus? Explain your reasoning.

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If neutral mutations occur at the rate of 0.5 per individual per generation, the rate of neutral substitutions per generation in that population will equal

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In a diploid population, the threshold at which selection will outweigh drift occurs when s (the selective advantage) is greater than

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Refer to the figure of the genetic code shown to answer the following question. Which of the following mutations to a codon is most likely to be selectively neutral? Refer to the figure of the genetic code shown to answer the following question. Which of the following mutations to a codon is most likely to be selectively neutral?

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Gene trees and species trees both depict evolutionary relationships. What is the difference between these two types of trees?

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