Exam 8: Evolution in Finite Populations
Exam 1: An Overview of Evolutionary Biology49 Questions
Exam 2: Early Evolutionary Ideas and Darwin S Insight49 Questions
Exam 3: Natural Selection47 Questions
Exam 4: Phylogeny and Evolutionary History47 Questions
Exam 5: Inferring Phylogeny46 Questions
Exam 6: Transmission Genetics and the Sources of Genetic Variation50 Questions
Exam 7: The Genetics of Populations46 Questions
Exam 8: Evolution in Finite Populations50 Questions
Exam 9: Evolution at Multiple Loci47 Questions
Exam 10: Genome Evolution49 Questions
Exam 11: The Origin and Evolution of Early Life50 Questions
Exam 12: Major Transitions47 Questions
Exam 13: Evolution and Development45 Questions
Exam 14: Species and Speciation48 Questions
Exam 15: Extinction and Evolutionary Trends49 Questions
Exam 16: The Evolution of Sex49 Questions
Exam 17: The Evolution of Sociality50 Questions
Exam 18: Coevolution50 Questions
Exam 19: Human Evolution49 Questions
Exam 20: Evolution and Medicine50 Questions
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How are the neutral theory of molecular evolution and the Hardy-Weinberg equilibrium similar?
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Both are used as null models in evolutionary biology.
The effective population size is often lower than the census size of a population because
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D
Consider a collection of 50 distinct alleles, each at equal frequency in a population. The time before the first coalescent event will be shortest if
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A
A researcher examines a microsatellite locus in a wild population of D. melanogaster. She finds that in a sample of 50 individuals, 20 different alleles are segregating. According to the neutral theory, these alleles are most likely experiencing
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The neutral theory predicts a constant rate of substitutions per generation; however, molecular clock estimates show that substitutions accumulate annually regardless of the generation time. What explanation for this discrepancy is illustrated in the figure? 

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Consider a population with an effective size of 4,000 and 32 segregating alleles. On average, how many generations would it take for all 32 alleles to coalesce to a single, ancestral allele?
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Consider a population of lizards living on the coast of Africa. A storm creates piles of debris that the lizards use to raft to a faraway uninhabited island. Which evolutionary process is happening?
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Consider a series of island populations each founded by a single individual that is heterozygous at a particular locus. If the alleles at this locus are neutral, and there is no mutation or migration, describe what the variation will look like after many generations within each population and between populations. Why?
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A rancher genotypes all of her 150 head of cattle. In her herd, 25 are A1A1, 75 are A1A2, and 50 are A2A2. Assuming there is random mating, no selection, no mutation, and no new cattle are introduced into the population, what is the probability that the A1 allele will be fixed?
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In the figure, assuming all evolutionary processes are similar in A-D, which genealogy is expected to carry the largest number of neutral alleles? 

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Why might a wind-pollinated plant experience different levels of diversity in mitochondrial versus nuclear loci following a postglacial recolonization event?
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The graphs show the results of simulations of changes in the frequency of a neutral allele. Each graph shows 10 different runs of the simulation. What is the most likely difference between these simulations? Explain your reasoning. A
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C




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Explain why the probability of fixation of a new beneficial allele is independent of population size
in Haldane's model of selection and drift.
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Consider two species, 1 and 2, that experience different mutation rates with m1 < m2, and have populations sizes of Ne1 < Ne2. Which species would you expect to have a lower frequency of heterozygotes at a neutral locus? Explain your reasoning.
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If neutral mutations occur at the rate of 0.5 per individual per generation, the rate of neutral substitutions per generation in that population will equal
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In a diploid population, the threshold at which selection will outweigh drift occurs when s (the selective advantage) is greater than
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Refer to the figure of the genetic code shown to answer the following question. Which of the following mutations to a codon is most likely to be selectively neutral? 

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Gene trees and species trees both depict evolutionary relationships. What is the difference between these two types of trees?
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