Question 1

Which drug is most widely used against malaria,except where resistant malaria is endemic to this medication?

Accepted Answer

A) quinidine gluconate 
B) primaquine (Malaride) 
C) chloroquine (Aralen) 
D) acyclovir (Zovirax) 
A) quinidine gluconate 
B) primaquine (Malaride) 
C) chloroquine (Aralen) 
D) acyclovir (Zovirax)

Question 2

Zanamivir (Relenza)is not indicated for children younger than:

Accepted Answer

A) 8 years. 
B) 7 year. 
C) 6 years. 
D) 5 years. 
A) 8 years. 
B) 7 year. 
C) 6 years. 
D) 5 years.

Question 3

Which drug is typically used to treat cryptococcal meningitis?

Accepted Answer

A) nystatin (Mycostatin) 
B) miconazole (Monistat) 
C) amphotericin B (Fungizone) 
D) clotrimazole (Gyne-Lotrimin) 
A) nystatin (Mycostatin) 
B) miconazole (Monistat) 
C) amphotericin B (Fungizone) 
D) clotrimazole (Gyne-Lotrimin)

Question 4

Benzimidazoles are metabolized via:

Accepted Answer

A) Urine. 
B) Feces. 
C) Liver. 
D) Large bowel. 
A) Urine. 
B) Feces. 
C) Liver. 
D) Large bowel.

Question 5

Which drug is used for prophylaxis of malaria in areas resistant to chloroquine (Aralen)?

Accepted Answer

A) primaquine (Malaride) 
B) quinidine gluconate 
C) pyrantel (Pin-Rid) 
D) piperazine 
A) primaquine (Malaride) 
B) quinidine gluconate 
C) pyrantel (Pin-Rid) 
D) piperazine

Question 6

When giving chloroquine,providers should be aware whether patients have which of the following?

Accepted Answer

A) Glucose-6-phosphate dehydrogenase (G-6-P
D)  
B) Hypertension 
C) Glaucoma 
D) Diabetes mellitus 
A) Glucose-6-phosphate dehydrogenase (G-6-P
D)  
B) Hypertension 
C) Glaucoma 
D) Diabetes mellitus

Question 7

In order to have any effect in treating an influenza infection in an elderly patient in a nursing home,amantadine must be administered:

Accepted Answer

A) To a patient with a full-functioning liver. 
B) To a patient within 48 hours of the onset of symptoms. 
C) In the absence of food. 
D) Administered with decongestants and antihistamines. 
A) To a patient with a full-functioning liver. 
B) To a patient within 48 hours of the onset of symptoms. 
C) In the absence of food. 
D) Administered with decongestants and antihistamines.

Question 8

The absorption of thiabendazole (Mintezol)is increased by the intake of which substance?

Accepted Answer

A) Orange juice 
B) Yogurt 
C) Fatty foods 
D) Skim milk 
A) Orange juice 
B) Yogurt 
C) Fatty foods 
D) Skim milk

Question 9

What is the mechanism of action for the imidazoles and triazoles?

Accepted Answer

A) Impair the synthesis of ergosterol which is necessary in fungal cell membranes 
B) Increase the synthesis of ergosterol which is necessary in fungal cell membranes 
C) Impair the synthesis of cholesterol which is necessary in fungal cell membranes 
D) Impair the synthesis of testosterone which is necessary in fungal cell membranes 
A) Impair the synthesis of ergosterol which is necessary in fungal cell membranes 
B) Increase the synthesis of ergosterol which is necessary in fungal cell membranes 
C) Impair the synthesis of cholesterol which is necessary in fungal cell membranes 
D) Impair the synthesis of testosterone which is necessary in fungal cell membranes

Question 10

Which of the following herpes mediations is not metabolized but is excreted in the urine as an unchanged drug?

Accepted Answer

A) acyclovir (Zovirax) 
B) penciclovir (Denavir) 
C) famciclovir (Famvir) 
D) valacyclovir (Valtrex) 
A) acyclovir (Zovirax) 
B) penciclovir (Denavir) 
C) famciclovir (Famvir) 
D) valacyclovir (Valtrex)

Question 11

When using metronidazole (Flagyl,Protostat)to treat bacterial vaginosis,what is the typical dosage?

Accepted Answer

A) 500 mg BID for 2 days 
B) 500 mg BID for 3 days 
C) 500 mg BID for 5 days 
D) 500 mg BID for 7 days 
A) 500 mg BID for 2 days 
B) 500 mg BID for 3 days 
C) 500 mg BID for 5 days 
D) 500 mg BID for 7 days

Question 12

Antimalarials are contraindicated with use of which other drug type?

Accepted Answer

A) Angiotensin-converting enzyme inhibitors 
B) Beta-adrenergic blockers 
C) Calcium channel blockers 
D) Diuretics 
A) Angiotensin-converting enzyme inhibitors 
B) Beta-adrenergic blockers 
C) Calcium channel blockers 
D) Diuretics

Question 13

What is the half-life of fluconazole?

Accepted Answer

A) 8 hours 
B) 21 hours 
C) 30 hours 
D) 64 hours 
A) 8 hours 
B) 21 hours 
C) 30 hours 
D) 64 hours

Question 14

Which option describes the mechanism of action of PIs?

Accepted Answer

A) Bind to an active site used by viral protease enzymes so they cannot process viral precursors critical to the maturation of HIV virus 
B) Bind to the active site of HIV reverse transcriptase and their antiviral activity is additive or synergistic with most other antiretrovirals 
C) Convert to active compounds in the presence of host enzymes,becoming part of the DNA chain,where they interfere with DNA synthesis and viral replication through their inhibition of viral RNA 
D) Compete with natural nucleotides in the host that would otherwise be incorporated into the newly synthesized DNA copies of the HIV virus;therefore,inhibit viral growth by terminating the virus' DNA chain 
A) Bind to an active site used by viral protease enzymes so they cannot process viral precursors critical to the maturation of HIV virus 
B) Bind to the active site of HIV reverse transcriptase and their antiviral activity is additive or synergistic with most other antiretrovirals 
C) Convert to active compounds in the presence of host enzymes,becoming part of the DNA chain,where they interfere with DNA synthesis and viral replication through their inhibition of viral RNA 
D) Compete with natural nucleotides in the host that would otherwise be incorporated into the newly synthesized DNA copies of the HIV virus;therefore,inhibit viral growth by terminating the virus' DNA chain

Question 15

Antimalarials are excreted via:

Accepted Answer

A) Stomach. 
B) Bile salts. 
C) Feces. 
D) Urine. 
A) Stomach. 
B) Bile salts. 
C) Feces. 
D) Urine.

Question 16

Pyrantel pamoate (Pin-Rid)is highly effective against which of the following?

Accepted Answer

A) Pinworm 
B) Hookworm 
C) Trichuriasis 
D) Strongyloidiasis 
A) Pinworm 
B) Hookworm 
C) Trichuriasis 
D) Strongyloidiasis

Question 17

What is the typical dosage of oseltamivir (Tamiflu)when used to treat influenza?

Accepted Answer

A) 50 mg BID 
B) 50 mg QD 
C) 75 mg BID. 
D) 75 mg BID 
A) 50 mg BID 
B) 50 mg QD 
C) 75 mg BID. 
D) 75 mg BID

Question 18

What is the mechanism of action of terbinafine?

Accepted Answer

A) Impairs the synthesis of ergosterol,which is necessary in fungal cell membranes 
B) Inhibits squalene 2,3-epoxidase,making it fungicidal to sensitive organisms 
C) Binds to microtubules comprising the spindles and inhibits fungal mitosis 
D) Disrupts DNA and protein synthesis in susceptible organisms 
A) Impairs the synthesis of ergosterol,which is necessary in fungal cell membranes 
B) Inhibits squalene 2,3-epoxidase,making it fungicidal to sensitive organisms 
C) Binds to microtubules comprising the spindles and inhibits fungal mitosis 
D) Disrupts DNA and protein synthesis in susceptible organisms

Question 19

In which pregnancy category are benzimidazoles?

Accepted Answer

A) Category A 
B) Category B 
C) Category C 
D) Category D 
A) Category A 
B) Category B 
C) Category C 
D) Category D

Question 20

PIs are excreted via:

Accepted Answer

A) Saliva. 
B) Urine. 
C) Bile salts. 
D) Feces. 
A) Saliva. 
B) Urine. 
C) Bile salts. 
D) Feces.

Exam 18: Drugs Used in the Treatment of Nonbacterial Infections

Which drug is most widely used against malaria,except where resistant malaria is endemic to this medication?

Zanamivir (Relenza)is not indicated for children younger than:

Which drug is typically used to treat cryptococcal meningitis?

Benzimidazoles are metabolized via:

Which drug is used for prophylaxis of malaria in areas resistant to chloroquine (Aralen)?

When giving chloroquine,providers should be aware whether patients have which of the following?

In order to have any effect in treating an influenza infection in an elderly patient in a nursing home,amantadine must be administered:

The absorption of thiabendazole (Mintezol)is increased by the intake of which substance?

What is the mechanism of action for the imidazoles and triazoles?

Which of the following herpes mediations is not metabolized but is excreted in the urine as an unchanged drug?

When using metronidazole (Flagyl,Protostat)to treat bacterial vaginosis,what is the typical dosage?

Antimalarials are contraindicated with use of which other drug type?

What is the half-life of fluconazole?

Which option describes the mechanism of action of PIs?

Antimalarials are excreted via:

Pyrantel pamoate (Pin-Rid)is highly effective against which of the following?

What is the typical dosage of oseltamivir (Tamiflu)when used to treat influenza?

What is the mechanism of action of terbinafine?

In which pregnancy category are benzimidazoles?

PIs are excreted via:

Conscientious and Rational Prescribing in the 21st Century

An Introduction to Pharmacodynamics and Pharmacokinetics

Communicating With Patients About Medications: a Patient-Centered Approach

Drugs Used in the Treatment of Bone and Joint Disorders

Drugs Used in the Treatment of Eye and Ear Disorders

Drugs Used in the Treatment of Cardiovascular Disorders

Drugs Used to Regulate Blood Pressure

Drugs Used in the Treatment of Hyperlipidemias

Drugs Used in the Treatment of Blood Disorders

Drugs Used in the Treatment of Pulmonary Diseases and Disorders

Drugs Used in the Treatment of Common Disorders of the Gastrointestinal System

Drugs Used to Treat Endocrine Gland Disorders

Drugs Used in the Treatment of Diabetes Mellitus

Drugs Used to Treat Common Neurological Conditions

Practical Pharmacotherapy of Drugs Used to Treat Psychiatric Disorders

Drugs Used in the Treatment of Skin Disorders

Modern Approaches to Managing Bacterial Infections

Drugs Used in the Treatment of Neoplasms

Drugs Used to Affect Womens Health

Drugs Used to Affect Mens Health

Prescribing for the Geriatric Patient

Prescribing for the Pediatric Patient

Drugs Used to Manage Pain

The Integrative Medicine Pharmacopoeia: Herbals, vitamins, and Dietary Supplements

Agents Used to Manipulate the Immune Response

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