Question 1

What is the appropriate dose of tiotropium (Spiriva)when treating chronic obstructive pulmonary disease (COPD)?

Accepted Answer

A) 10 mcg once a day 
B) 10 mcg twice a day 
C) 18 mcg once a day 
D) 18 mcg twice a day 
A) 10 mcg once a day 
B) 10 mcg twice a day 
C) 18 mcg once a day 
D) 18 mcg twice a day

Question 2

Which of the following describes the mechanism of action of zafirlukast?

Accepted Answer

A) Selective competitive inhibitor of leukotriene receptors D4 and E4 
B) Nonselective competitive inhibitor of leukotriene receptors D4 and E4 
C) Selective competitive agonist of leukotriene receptors D4 and E4 
D) Nonselective competitive agonist of leukotriene receptors D4 and E4 
A) Selective competitive inhibitor of leukotriene receptors D4 and E4 
B) Nonselective competitive inhibitor of leukotriene receptors D4 and E4 
C) Selective competitive agonist of leukotriene receptors D4 and E4 
D) Nonselective competitive agonist of leukotriene receptors D4 and E4

Question 3

What is the duration of action for all long-acting beta agonists?

Accepted Answer

A) 4 hours 
B) 8 hours 
C) 12 hours 
D) 16 hours 
A) 4 hours 
B) 8 hours 
C) 12 hours 
D) 16 hours

Question 4

A common adverse reaction when using a codeine-based antitussive is:

Accepted Answer

A) Hypertension. 
B) Headache. 
C) Insomnia. 
D) Constipation. 
A) Hypertension. 
B) Headache. 
C) Insomnia. 
D) Constipation.

Question 5

Antitussives are contraindicated in patients who use:

Accepted Answer

A) Monoamine oxidase inhibitors. 
B) Selective serotonin reuptake inhibitors. 
C) Tricyclics. 
D) Wellbutrin. 
A) Monoamine oxidase inhibitors. 
B) Selective serotonin reuptake inhibitors. 
C) Tricyclics. 
D) Wellbutrin.

Question 6

What is the mechanism of action of omalizumab?

Accepted Answer

A) Selectively binds to human immunoglobulin E (Ig
E) receptors on mast cells and eosinophils 
B) Blocks the production of leukotriene B4,another arachidonic acid metabolite with proinflammatory activity 
C) Performs as a selective competitive antagonist of the cysteinyl-leukotriene receptor and another receptor D4 
D) Prevents the release of mediators of type 1 allergic reactions,including histamine 
A) Selectively binds to human immunoglobulin E (Ig
E) receptors on mast cells and eosinophils 
B) Blocks the production of leukotriene B4,another arachidonic acid metabolite with proinflammatory activity 
C) Performs as a selective competitive antagonist of the cysteinyl-leukotriene receptor and another receptor D4 
D) Prevents the release of mediators of type 1 allergic reactions,including histamine

Question 7

Patients should not take albuterol/ipratropium if they are allergic to:

Accepted Answer

A) Alcohol. 
B) Milk. 
C) Peanuts. 
D) Oranges. 
A) Alcohol. 
B) Milk. 
C) Peanuts. 
D) Oranges.

Question 8

When salmeterol (Serevent)is used to treat exercise-induced asthma,how should it be dosed?

Accepted Answer

A) One inhalation 5 minutes before exercise 
B) One inhalation 10 minutes before exercise 
C) One inhalation 20 minutes before exercise 
D) One inhalation 30 minutes before exercise 
A) One inhalation 5 minutes before exercise 
B) One inhalation 10 minutes before exercise 
C) One inhalation 20 minutes before exercise 
D) One inhalation 30 minutes before exercise

Question 9

Antihistamines are rapidly absorbed after:

Accepted Answer

A) Intranasal administration. 
B) Oral administration. 
C) Subcutaneous administration. 
D) Transdermal administration. 
A) Intranasal administration. 
B) Oral administration. 
C) Subcutaneous administration. 
D) Transdermal administration.

Question 10

When using beta-2 receptor agonists,the patient should undergo periodic measurement of:

Accepted Answer

A) Intraocular pressure. 
B) Glucose level. 
C) Urine specific gravity. 
D) Liver function. 
A) Intraocular pressure. 
B) Glucose level. 
C) Urine specific gravity. 
D) Liver function.

Question 11

What is a common dosage for antitussives?

Accepted Answer

A) 5 to 10 mg every 4 hours 
B) 10 to 20 mg every 4 hours 
C) 20 to 30 mg every 4 hours 
D) 30 to 40 mg every 4 hours 
A) 5 to 10 mg every 4 hours 
B) 10 to 20 mg every 4 hours 
C) 20 to 30 mg every 4 hours 
D) 30 to 40 mg every 4 hours

Question 12

Oral corticosteroids are secreted via:

Accepted Answer

A) Bile. 
B) Urine. 
C) Feces. 
D) Multiple organs. 
A) Bile. 
B) Urine. 
C) Feces. 
D) Multiple organs.

Question 13

What is the mechanism of action of long-acting beta agonists?

Accepted Answer

A) Stimulation of beta-2 antagonist receptors in the lungs,resulting in a relaxation of bronchial smooth muscle 
B) Stimulation of beta-2 adrenergic receptors in the lungs,resulting in a relaxation of bronchial smooth muscle 
C) Stimulation of beta-2 adrenergic receptors in the lungs,resulting in a contraction of bronchial smooth muscle 
D) Decreased stimulation of beta-2 adrenergic receptors in the lungs,resulting in a relaxation of bronchial smooth muscle 
A) Stimulation of beta-2 antagonist receptors in the lungs,resulting in a relaxation of bronchial smooth muscle 
B) Stimulation of beta-2 adrenergic receptors in the lungs,resulting in a relaxation of bronchial smooth muscle 
C) Stimulation of beta-2 adrenergic receptors in the lungs,resulting in a contraction of bronchial smooth muscle 
D) Decreased stimulation of beta-2 adrenergic receptors in the lungs,resulting in a relaxation of bronchial smooth muscle

Question 14

Which substance increases xanthine derivative levels?

Accepted Answer

A) St.John's Wort 
B) capsaicin 
C) melatonin 
D) chondroitin 
A) St.John's Wort 
B) capsaicin 
C) melatonin 
D) chondroitin

Question 15

What is the half-life of prednisone?

Accepted Answer

A) 1.5 to 2.5 hours 
B) 2 to 3 hours 
C) 2.5 to 3.5 hours 
D) 3 to 4 hours 
A) 1.5 to 2.5 hours 
B) 2 to 3 hours 
C) 2.5 to 3.5 hours 
D) 3 to 4 hours

Question 16

How is omalizumab (Xolair)given?

Accepted Answer

A) Orally 
B) Intravenously 
C) Transdermally 
D) Subcutaneously 
A) Orally 
B) Intravenously 
C) Transdermally 
D) Subcutaneously

Question 17

One common dermatological side effect of long-term use of oral prednisone is:

Accepted Answer

A) Acne. 
B) Contact dermatitis. 
C) Oral herpes simplex. 
D) Tinea capitis. 
A) Acne. 
B) Contact dermatitis. 
C) Oral herpes simplex. 
D) Tinea capitis.

Question 18

When a patient is taking oral corticosteroids,which other medication may need to be adjusted?

Accepted Answer

A) simvastatin (Zocor) 
B) insulin 
C) minoxidil (Loniten) 
D) metoprolol (Lopressor) 
A) simvastatin (Zocor) 
B) insulin 
C) minoxidil (Loniten) 
D) metoprolol (Lopressor)

Question 19

How is albuterol/ipratropium (Combivent)typically taken?

Accepted Answer

A) 1 or 2 inhalations every 4 to 6 hours 
B) 1 or 2 inhalations every 12 hours 
C) 1 or 2 inhalations every 24 hours 
D) 2 to 4 inhalations every 4 to 6 hours 
A) 1 or 2 inhalations every 4 to 6 hours 
B) 1 or 2 inhalations every 12 hours 
C) 1 or 2 inhalations every 24 hours 
D) 2 to 4 inhalations every 4 to 6 hours

Question 20

Montelukast can be used to treat chronic asthma in which age group?

Accepted Answer

A) Children age 1 and older 
B) Children age 5 years and older 
C) Children age 7 years and older 
D) Children age 12 years and older 
A) Children age 1 and older 
B) Children age 5 years and older 
C) Children age 7 years and older 
D) Children age 12 years and older

Exam 10: Drugs Used in the Treatment of Pulmonary Diseases and Disorders

What is the appropriate dose of tiotropium (Spiriva)when treating chronic obstructive pulmonary disease (COPD)?

Which of the following describes the mechanism of action of zafirlukast?

What is the duration of action for all long-acting beta agonists?

A common adverse reaction when using a codeine-based antitussive is:

Antitussives are contraindicated in patients who use:

What is the mechanism of action of omalizumab?

Patients should not take albuterol/ipratropium if they are allergic to:

When salmeterol (Serevent)is used to treat exercise-induced asthma,how should it be dosed?

Antihistamines are rapidly absorbed after:

When using beta-2 receptor agonists,the patient should undergo periodic measurement of:

What is a common dosage for antitussives?

Oral corticosteroids are secreted via:

What is the mechanism of action of long-acting beta agonists?

Which substance increases xanthine derivative levels?

What is the half-life of prednisone?

How is omalizumab (Xolair)given?

One common dermatological side effect of long-term use of oral prednisone is:

When a patient is taking oral corticosteroids,which other medication may need to be adjusted?

How is albuterol/ipratropium (Combivent)typically taken?

Montelukast can be used to treat chronic asthma in which age group?

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