Question 1

While on statin therapy,a patient should limit which common beverage?

Accepted Answer

A) Milk 
B) Apple juice 
C) Grapefruit juice 
D) Soda 
A) Milk 
B) Apple juice 
C) Grapefruit juice 
D) Soda

Question 2

What is the half-life of ezetimibe (Zetia)?

Accepted Answer

A) 12 hours 
B) 22 hours 
C) 28 hours 
D) 32 hours 
A) 12 hours 
B) 22 hours 
C) 28 hours 
D) 32 hours

Question 3

Statins are metabolized via the:

Accepted Answer

A) Kidneys. 
B) Liver. 
C) Large bowel. 
D) Small bowel. 
A) Kidneys. 
B) Liver. 
C) Large bowel. 
D) Small bowel.

Question 4

Any statin can be used to treat which condition?

Accepted Answer

A) Heterozygous familial hypercholesterolemia in adolescents 
B) Homozygous familial hyperlipidemia 
C) Hypertriglyceridemia 
D) Mixed dyslipidemia 
A) Heterozygous familial hypercholesterolemia in adolescents 
B) Homozygous familial hyperlipidemia 
C) Hypertriglyceridemia 
D) Mixed dyslipidemia

Question 5

When niacin is given concomitantly with some antihypertensive medications,which reaction can occur?

Accepted Answer

A) Headache 
B) Postural hypotension 
C) Postural hypertension 
D) Vomiting 
A) Headache 
B) Postural hypotension 
C) Postural hypertension 
D) Vomiting

Question 6

What is the typical dose of ezetimibe (Zetia)?

Accepted Answer

A) 5 mg 
B) 10 mg 
C) 15 mg 
D) 20 mg 
A) 5 mg 
B) 10 mg 
C) 15 mg 
D) 20 mg

Question 7

Vytorin is a common combined drug used to treat elevated cholesterol that is composed of which two drugs?

Accepted Answer

A) amlodipine besylate and atorvastatin calcium 
B) niacin and lovastatin 
C) ezetimibe and simvastatin 
D) niacin and simvastatin 
A) amlodipine besylate and atorvastatin calcium 
B) niacin and lovastatin 
C) ezetimibe and simvastatin 
D) niacin and simvastatin

Question 8

Which option describes the mechanism of action of statins?

Accepted Answer

A) Enhances conversion of 3-hydroxy-3 methylglutaryl coenzyme A (HMG-Co
A) ,the transmembrane protein that catalyzes a key step in the mevalonate pathway 
B) Inhibits conversion of HMG-CoA 
C) Increases fatty acid release from adipose tissue and inhibits fatty acid and triglyceride synthesis in the liver 
D) Increases fatty acid release from adipose tissue and increases fatty acid and triglyceride synthesis in the liver 
A) Enhances conversion of 3-hydroxy-3 methylglutaryl coenzyme A (HMG-Co
A) ,the transmembrane protein that catalyzes a key step in the mevalonate pathway 
B) Inhibits conversion of HMG-CoA 
C) Increases fatty acid release from adipose tissue and inhibits fatty acid and triglyceride synthesis in the liver 
D) Increases fatty acid release from adipose tissue and increases fatty acid and triglyceride synthesis in the liver

Question 9

Bile acid sequestrants cause which effects?

Accepted Answer

A) Reduce LDL and HDL cholesterol 
B) Reduce LDL cholesterol and increase HDL cholesterol 
C) Reduce LDL and total cholesterol 
D) Reduce LDL cholesterol and increase triglycerides 
A) Reduce LDL and HDL cholesterol 
B) Reduce LDL cholesterol and increase HDL cholesterol 
C) Reduce LDL and total cholesterol 
D) Reduce LDL cholesterol and increase triglycerides

Question 10

Bile acid sequestrants are not recommended for monotherapy if triglyceride levels are more than:

Accepted Answer

A) 100 mg/dl. 
B) 200 mg/dl. 
C) 300 mg/dl. 
D) 400 mg/dl. 
A) 100 mg/dl. 
B) 200 mg/dl. 
C) 300 mg/dl. 
D) 400 mg/dl.

Question 11

What is the staring dose of ezetimibe/simvastatin (Vytorin)?

Accepted Answer

A) 5 mg/10 mg 
B) 10 mg/10 mg 
C) 10 mg/20 mg 
D) 20 mg/20 mg 
A) 5 mg/10 mg 
B) 10 mg/10 mg 
C) 10 mg/20 mg 
D) 20 mg/20 mg

Question 12

Which natural product may reduce the effectiveness of statins?

Accepted Answer

A) Yohimbe 
B) St.John's wort 
C) Vitamin C 
D) Chromium 
A) Yohimbe 
B) St.John's wort 
C) Vitamin C 
D) Chromium

Question 13

What is the trade name for clofibrate?

Accepted Answer

A) TriCor 
B) Triglide 
C) Antara 
D) Atromid-S 
A) TriCor 
B) Triglide 
C) Antara 
D) Atromid-S

Question 14

Bile acid sequestrants may cause a deficiency of which vitamin?

Accepted Answer

A) Vitamin A 
B) Vitamin B1 
C) Vitamin B6 
D) Vitamin C 
A) Vitamin A 
B) Vitamin B1 
C) Vitamin B6 
D) Vitamin C

Question 15

What is the mechanism of action of niacin?

Accepted Answer

A) Inhibits fatty acid release from adipose tissue and inhibits fatty acid and triglyceride synthesis in the liver 
B) Increases fatty acid release from adipose tissue and inhibits fatty acid and triglyceride synthesis in the liver 
C) Increases fatty acid release from adipose tissue and increases fatty acid and triglyceride synthesis in the liver 
D) Inhibits fatty acid release from adipose tissue and increases fatty acid and triglyceride synthesis in the liver 
A) Inhibits fatty acid release from adipose tissue and inhibits fatty acid and triglyceride synthesis in the liver 
B) Increases fatty acid release from adipose tissue and inhibits fatty acid and triglyceride synthesis in the liver 
C) Increases fatty acid release from adipose tissue and increases fatty acid and triglyceride synthesis in the liver 
D) Inhibits fatty acid release from adipose tissue and increases fatty acid and triglyceride synthesis in the liver

Question 16

Which of the following is a cardiovascular adverse reaction that can occur in patients taking gemfibrozil (Lopid)?

Accepted Answer

A) Myocardial infarction 
B) Arrhythmias 
C) Hypertension 
D) Hypotension 
A) Myocardial infarction 
B) Arrhythmias 
C) Hypertension 
D) Hypotension

Question 17

The half-life of rosuvastatin (Crestor)is:

Accepted Answer

A) 1.2 hours. 
B) 2 hours. 
C) 14 hours. 
D) 19 hours. 
A) 1.2 hours. 
B) 2 hours. 
C) 14 hours. 
D) 19 hours.

Question 18

When concomitantly taking a bile acid sequestrant,ezetimibe (Zetia)can be taken:

Accepted Answer

A) At the same time as the bile acid sequestrant. 
B) 30 minutes before taking the bile acid sequestrant. 
C) 60 minutes before taking the bile acid sequestrant. 
D) 120 minutes before taking the bile acid sequestrant. 
A) At the same time as the bile acid sequestrant. 
B) 30 minutes before taking the bile acid sequestrant. 
C) 60 minutes before taking the bile acid sequestrant. 
D) 120 minutes before taking the bile acid sequestrant.

Question 19

The most common adverse effect of niacin and the number one reason it is discontinued is:

Accepted Answer

A) Headache. 
B) Muscle pain. 
C) Facial flushing. 
D) Elevations of liver enzymes. 
A) Headache. 
B) Muscle pain. 
C) Facial flushing. 
D) Elevations of liver enzymes.

Question 20

After oral administration,what percentage of fibric acid derivatives is absorbed?

Accepted Answer

A) 10% 
B) 20% 
C) 40% 
D) 60% 
A) 10% 
B) 20% 
C) 40% 
D) 60%

Exam 8: Drugs Used in the Treatment of Hyperlipidemias

While on statin therapy,a patient should limit which common beverage?

What is the half-life of ezetimibe (Zetia)?

Statins are metabolized via the:

Any statin can be used to treat which condition?

When niacin is given concomitantly with some antihypertensive medications,which reaction can occur?

What is the typical dose of ezetimibe (Zetia)?

Vytorin is a common combined drug used to treat elevated cholesterol that is composed of which two drugs?

Which option describes the mechanism of action of statins?

Bile acid sequestrants cause which effects?

Bile acid sequestrants are not recommended for monotherapy if triglyceride levels are more than:

What is the staring dose of ezetimibe/simvastatin (Vytorin)?

Which natural product may reduce the effectiveness of statins?

What is the trade name for clofibrate?

Bile acid sequestrants may cause a deficiency of which vitamin?

What is the mechanism of action of niacin?

Which of the following is a cardiovascular adverse reaction that can occur in patients taking gemfibrozil (Lopid)?

The half-life of rosuvastatin (Crestor)is:

When concomitantly taking a bile acid sequestrant,ezetimibe (Zetia)can be taken:

The most common adverse effect of niacin and the number one reason it is discontinued is:

After oral administration,what percentage of fibric acid derivatives is absorbed?

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Drugs Used in the Treatment of Cardiovascular Disorders

Drugs Used to Regulate Blood Pressure

Drugs Used in the Treatment of Blood Disorders

Drugs Used in the Treatment of Pulmonary Diseases and Disorders

Drugs Used in the Treatment of Common Disorders of the Gastrointestinal System

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Drugs Used in the Treatment of Nonbacterial Infections

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Prescribing for the Pediatric Patient

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