Exam 8: Gene Expression: the Flow of Information From Dna to Rna to Protein

Many cancers have a mutation that changes a valine to a glutamic acid in the RAF kinase protein which phosphorylates proteins that promote cell division.This mutant protein is a constitutively active kinase.What type of allele is this mutant allele?

The DNA sequence 5′ ATGGGGGACACC 3′ encodes the amino acids Met Gly Asp Thr.A mutation changes the sequence to 5′ ATGGGTGACACC 3′, but the same amino acids are encoded.What type of mutation has occurred?

A large deletion removes the promoter and first three exons of a gene.No mRNA or protein is detected.What type of allele is this mutant allele?

The wobble base of a tRNA is

A tRNA with the anticodon sequence 5′ IUC 3′ will not normally exist because

The appearance of a novel phenotype resulting from the substitution of a single base pair might be due to

A prokaryotic large ribosomal subunit is composed of

A mutation that changes a codon sequence, and subsequently changes the amino acid that should have been placed at that point in the polypeptide chain, is a

A codon is a three-base sequence of

How many different amino acids could be encoded by the synthetic mRNA sequence 5' UGCUGCUGC 3'?

A mutation that is characterized by a change in the DNA sequence, but no change in the resulting protein sequence, is a

When the anticodon of a tRNA and the codon of an mRNA interact, the two sequences are

The retroviruses, including HIV, are unique because they use

Experiments that are done inside a living cell are described by the Latin term

The DNA sequence 5′ ATGGGGGACACC 3′ encodes the amino acids Met Gly Asp Thr.A mutation changes the sequence to 5′ ATGGGGAACACC 3′ that encodes the amino acids Met Gly Asn Thr.What type of mutation has occurred?

An anticodon of sequence 5′ GUA 3′ will recognize the codon sequence

The Central Dogma describes the flow of genetic information as

A mutation that changes a codon that originally coded for an amino acid into a stop codon is a

The sequences found in a mature eukaryotic mRNAs are

A DNA sequence 5′ ATGGGGGACACC 3′ encodes the amino acids Met Gly Asp Thr.A mutation changes the sequence to 5′ ATGAGGGGACACC 3′ that encodes the amino acids Met Arg Gly His.What type of mutation has occurred?