Question 1

Interaction between two distinct polypeptide chains is what type of structure in a protein?

Accepted Answer

A) primary structure 
B) secondary structure 
C) tertiary structure 
D) quaternary structure 
E) both primary and secondary structure 
A) primary structure 
B) secondary structure 
C) tertiary structure 
D) quaternary structure 
E) both primary and secondary structure

Question 2

What is the consequence to a bacterial cell of a mutation that inactivates the enzyme responsible for methylating the A in the DNA sequence 5′ GATC?

Accepted Answer

A) Replication of the lagging strand cannot be completed. 
B) Thymine dimers cannot be repaired. 
C) Parental and new DNA strands cannot be distinguished during mismatch repair. 
D) Expression of certain metabolic genes is decreased. 
E) The mutation rate of all genes will be lower. 
A) Replication of the lagging strand cannot be completed. 
B) Thymine dimers cannot be repaired. 
C) Parental and new DNA strands cannot be distinguished during mismatch repair. 
D) Expression of certain metabolic genes is decreased. 
E) The mutation rate of all genes will be lower.

Question 3

What does the hydrolysis of a purine base from the deoxyribose-phosphate backbone leave behind?

Accepted Answer

A) an apurinic site 
B) a modified base 
C) a double-strand break 
D) a mutation 
E) a deletion 
A) an apurinic site 
B) a modified base 
C) a double-strand break 
D) a mutation 
E) a deletion

Question 4

What statement about biochemical pathways is correct?

Accepted Answer

A) All enzymes in the pathway catalyze the same reaction. 
B) If an enzyme in a pathway is inactive, adding excessive amounts of its substrate will restore the normal phenotype. 
C) If an enzyme in a pathway is inactive, adding excessive amounts of its product will restore the normal phenotype. 
D) If the enzyme that catalyzes the final step in a pathway is inactive, all the other enzymes will be inactivated as well. 
E) If the first enzyme in a pathway is inactivated, adding the final product will not restore the normal phenotype. 
A) All enzymes in the pathway catalyze the same reaction. 
B) If an enzyme in a pathway is inactive, adding excessive amounts of its substrate will restore the normal phenotype. 
C) If an enzyme in a pathway is inactive, adding excessive amounts of its product will restore the normal phenotype. 
D) If the enzyme that catalyzes the final step in a pathway is inactive, all the other enzymes will be inactivated as well. 
E) If the first enzyme in a pathway is inactivated, adding the final product will not restore the normal phenotype.

Question 5

Which condition does not involve a defect in an enzyme pathway?

Accepted Answer

A) Alkaptonuria 
B) Albinism 
C) Sickle cell anemia 
D) Phenylketonuria (PKU) 
A) Alkaptonuria 
B) Albinism 
C) Sickle cell anemia 
D) Phenylketonuria (PKU)

Question 6

What level(s)of protein structure could be affected by a nucleotide substitution that results in an amino acid change in a polypeptide? (Select all that apply. )

Accepted Answer

A) primary structure 
B) secondary structure 
C) tertiary structure 
D) quaternary structure 
E) There will be no structural changes. 
A) primary structure 
B) secondary structure 
C) tertiary structure 
D) quaternary structure 
E) There will be no structural changes.

Question 7

In a segment of DNA, an A base is changed to a C and the error is copied during replication.Under which circumstances is that change considered a mutation? (Select all that apply. )

Accepted Answer

A) The change alters the phenotype of the organism's offspring. 
B) The change results in production of a novel protein. 
C) The change is in a somatic cell, such as a skin cell. 
D) The change is in a gene, but has no effect on a gene product or phenotype. 
A) The change alters the phenotype of the organism's offspring. 
B) The change results in production of a novel protein. 
C) The change is in a somatic cell, such as a skin cell. 
D) The change is in a gene, but has no effect on a gene product or phenotype.

Question 8

Thymine dimers are caused by

Accepted Answer

A) X-rays. 
B) active oxygen species. 
C) a mutagen such as ethylmethane sulfonate (EMS). 
D) depurination. 
E) UV light. 
A) X-rays. 
B) active oxygen species. 
C) a mutagen such as ethylmethane sulfonate (EMS). 
D) depurination. 
E) UV light.

Question 9

Exposure to UV light from the sun or tanning beds causes

Accepted Answer

A) depurination. 
B) deamination. 
C) alkylation. 
D) thymine dimers. 
E) oxidation. 
A) depurination. 
B) deamination. 
C) alkylation. 
D) thymine dimers. 
E) oxidation.

Question 10

In a test tube, a particular DNA polymerase has an error rate of 1 mistake in every 106 bases copied.Why is the mutation rate in a cell that uses this DNA polymerase much lower?

Accepted Answer

A) The polymerase is more careful in replicating regions where genes exist. 
B) Repair mechanisms correct errors made by the polymerase. 
C) Not all mutations can be detected easily. 
D) The DNA polymerase has no proofreading function. 
E) Mutations do not occur if mutagens are not present. 
A) The polymerase is more careful in replicating regions where genes exist. 
B) Repair mechanisms correct errors made by the polymerase. 
C) Not all mutations can be detected easily. 
D) The DNA polymerase has no proofreading function. 
E) Mutations do not occur if mutagens are not present.

Question 11

Replacing a thymine nucleotide with a guanine is an example of a

Accepted Answer

A) translocation. 
B) transition. 
C) transversion. 
D) forward mutation. 
E) reversion or reverse mutation 
A) translocation. 
B) transition. 
C) transversion. 
D) forward mutation. 
E) reversion or reverse mutation

Interaction between two distinct polypeptide chains is what type of structure in a protein?

What is the consequence to a bacterial cell of a mutation that inactivates the enzyme responsible for methylating the A in the DNA sequence 5′ GATC?

What does the hydrolysis of a purine base from the deoxyribose-phosphate backbone leave behind?

What statement about biochemical pathways is correct?

Which condition does not involve a defect in an enzyme pathway?

What level(s)of protein structure could be affected by a nucleotide substitution that results in an amino acid change in a polypeptide? (Select all that apply. )

In a segment of DNA, an A base is changed to a C and the error is copied during replication.Under which circumstances is that change considered a mutation? (Select all that apply. )

Thymine dimers are caused by

Exposure to UV light from the sun or tanning beds causes

In a test tube, a particular DNA polymerase has an error rate of 1 mistake in every 106 bases copied.Why is the mutation rate in a cell that uses this DNA polymerase much lower?

Replacing a thymine nucleotide with a guanine is an example of a

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

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Exam 7: Anatomy and Function of a Gene: Dissection Through Mutation

Interaction between two distinct polypeptide chains is what type of structure in a protein?

What is the consequence to a bacterial cell of a mutation that inactivates the enzyme responsible for methylating the A in the DNA sequence 5′ GATC?

What does the hydrolysis of a purine base from the deoxyribose-phosphate backbone leave behind?

What statement about biochemical pathways is correct?

Which condition does not involve a defect in an enzyme pathway?

What level(s)of protein structure could be affected by a nucleotide substitution that results in an amino acid change in a polypeptide? (Select all that apply. )

In a segment of DNA, an A base is changed to a C and the error is copied during replication.Under which circumstances is that change considered a mutation? (Select all that apply. )

Thymine dimers are caused by

Exposure to UV light from the sun or tanning beds causes

In a test tube, a particular DNA polymerase has an error rate of 1 mistake in every 106 bases copied.Why is the mutation rate in a cell that uses this DNA polymerase much lower?

Replacing a thymine nucleotide with a guanine is an example of a

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters