Question 1

What does the data analysis allow you to conclude about linkage between sn and car? (Select all that apply. )

Accepted Answer

A) There is a high probability that the deviations from the expected number of F2 in each genotype class are due to chance. 
B) The data do not allow rejection of the null hypothesis. 
C) The p value is high meaning that the data is significant. 
D) There is good evidence that cn and car are linked. 
A) There is a high probability that the deviations from the expected number of F2 in each genotype class are due to chance. 
B) The data do not allow rejection of the null hypothesis. 
C) The p value is high meaning that the data is significant. 
D) There is good evidence that cn and car are linked.

Question 2

In Neurospora, the white-spore allele (ws) results in white spores rather than the wild-type black spores. Diploid ws / ws+ cells undergo meiosis followed by one round of mitosis to form ordered tetrads. Indicate if the pattern of spores seen in the tetrads are consistent with first-division or second-division segregation.
-ws+; ws+; ws; ws; ws+; ws+; ws; ws

Accepted Answer

A) first-division segregation pattern 
B) second-division segregation pattern 
A) first-division segregation pattern 
B) second-division segregation pattern

Question 3

A female mouse from a true-breeding wild-type strain was crossed to a male mouse with apricot eyes (ap)and grey body (gy).The F1 mice were wild-type for both traits.When the F1 were interbred, the F2 were distributed as follows: Females
$$\begin{array} { | l | l | } 
\hline \text { all wild type } & 200 \
\hline
\end{array}$$ Males
$$\begin{array} { | l | r | } 
\hline \text { wild type } & 91 \
\hline \text { apricot } & 11 \
\hline \text { grey } & 9 \
\hline \text { apricot, grey } & 89 \
\hline
\end{array}$$ Which of the following statements is correct?

Accepted Answer

A) ap and gy are unlinked 
B) ap and gy are linked on an autosome and 10 map units apart 
C) ap and gy are linked on an autosome and 20 map units apart 
D) ap and gy are X-linked and 10 map units apart 
E) ap and gy are X-linked and 20 map units apart 
A) ap and gy are unlinked 
B) ap and gy are linked on an autosome and 10 map units apart 
C) ap and gy are linked on an autosome and 20 map units apart 
D) ap and gy are X-linked and 10 map units apart 
E) ap and gy are X-linked and 20 map units apart

Question 4

In peas, tall (T)is dominant to short (t), red flowers (R)is dominant to white flowers (r), and wide leaves (W)is dominant to narrow leaves (w).A tall plant that has red flowers and wide leaves is crossed to a short plant that has white flowers and narrow leaves.The resulting progeny are shown in the table.
 $\begin{array}{|l|r|}
\hline \text { tall, red, wide } & 381 \
\hline \text { tall, white, wide } & 122 \
\hline \text { short, red, wide } & 118 \
\hline \text { short, white, wide } & 379 \
\hline & 1000 \
\hline
\end{array}$
-What is the genotype of the tall plant that has red flowers and wide leaves?

Accepted Answer

A) T R W / t r w 
B) T R W / t r W? 
C) T R W / T R W? 
D) T R W / T r w? 
E) T r W / t R W? 
A) T R W / t r w 
B) T R W / t r W? 
C) T R W / T R W? 
D) T R W / T r w? 
E) T r W / t R W?

Question 5

In Drosophila, the genes y, f, and v are all X-linked. Females who are homozygous for recessive alleles of all three genes (y f v / y f v) are crossed to wild-type males. The resulting trihybrid F1 females are testcrossed. The F2 are distributed as follows:

$$\begin{array} { | l | r | } 
\hline y f v & 3210 \
\hline y f v ^ { + } & 72 \
\hline y f ^ { + } v & 1024 \
\hline y f ^ { + } v^ + & 678 \
\hline y ^ { + } f v & 690 \
\hline y ^ { + } f v ^+ & 1044 \
\hline y ^ { + } f ^+ v & 60 \
\hline y ^ { + } f ^+ v^ + & 3222 \
\hline & 10,000 \
\hline
\end{array}$$

-What is the coefficient of coincidence in this region?

Accepted Answer

A) 0 
B) 0.2 
C) 0.4 
D) 0.6 
E) 0.8 
A) 0 
B) 0.2 
C) 0.4 
D) 0.6 
E) 0.8

Question 6

In Neurospora, the white-spore allele (ws) results in white spores rather than the wild-type black spores. Diploid ws / ws+ cells undergo meiosis followed by one round of mitosis to form ordered tetrads. Indicate if the pattern of spores seen in the tetrads are consistent with first-division or second-division segregation.
-ws; ws; ws+; ws+; ws; ws; ws+; ws+

Accepted Answer

A) first-division segregation pattern 
B) second-division segregation pattern 
A) first-division segregation pattern 
B) second-division segregation pattern

Question 7

A dihybrid testcross is made to determine if genes C and D are linked.The results are shown in the table.
 $\begin{array}{|l|c|r|}
\hline \text { Parent genotypes: } & C c  D d \times c c d d & \
\hline & C c  D d & 222 \
\hline & C c  d d & 280 \
\hline \text { Progeny genotypes: } & c c  D d & 280 \
\hline & c c  d d & 218 \
\hline & & 1000 \
\hline
\end{array}$  
-Given this data, use Table 5.2 to find the most accurate range within which the p value falls.

Accepted Answer

A) 0.001 < p < 0.01 
B) 0.01 < p < 0.05 
C) 0.05 < p < 0.10 
D) 0.10 < p < 0.50 
A) 0.001 < p < 0.01 
B) 0.01 < p < 0.05 
C) 0.05 < p < 0.10 
D) 0.10 < p < 0.50

Question 8

Females heterozygous for the recessive second chromosome mutations px, sp, and cn are mated to a male homozygous for all three mutations.The offspring are as follows:
 $\begin{array}{|l|r|}
\hline p x  s p  c n & 1461 \
\hline p x  s p  c n^{+} & 3497 \
\hline p x  s p{+ c n} & 1\
\hline p x  s p^{+}  c n+ & 11 \
\hline p x^{+}  s p  c n & 9 \
\hline p x^{+}  s p  c n+ & 0 \
\hline p x^{+}  s p+ c n & 3483 \
\hline p x^{+}  s p+ c n+ & 1539 \
\hline & 10,000 \
\hline
\end{array}$
-Which of the three genes is in the middle?

Accepted Answer

A) px 
B) sp 
C) cn 
D) insufficient data 
A) px 
B) sp 
C) cn 
D) insufficient data

Question 9

The map of a chromosome interval is: A--10 m.u.--B--40 m.u.--C
From the cross A b c / a B C × a b c / a b c, how many double crossovers would be expected out of 1000 progeny?

Accepted Answer

A) 5 
B) 10 
C) 20 
D) 40 
E) 80 
A) 5 
B) 10 
C) 20 
D) 40 
E) 80

Question 10

The cross L p q / l P Q × l p q / l p q is carried out.If the L gene is in the middle, between genes P and Q, what would be the genotypes of the double crossover gametes in this cross?

Accepted Answer

A) L P Q and l p q 
B) L p Q and l P q 
C) l p Q and L P q 
D) L p q and l P Q 
E) cannot be determined 
A) L P Q and l p q 
B) L p Q and l P q 
C) l p Q and L P q 
D) L p q and l P Q 
E) cannot be determined

Question 11

Individuals heterozygous for the RB+ and RB− alleles can develop tumors as a result of (Select all that apply. )

Accepted Answer

A) a mitotic crossover that leads to homozygosity for RB+ in some cells and RB− in other cells. 
B) a somatic mutation in the RB+ allele that leads to homozygosity for RB−. 
C) a somatic mutation in the RB− allele that leads to homozygosity for RB+. 
D) the fact that RB− is dominant to RB+. 
A) a mitotic crossover that leads to homozygosity for RB+ in some cells and RB− in other cells. 
B) a somatic mutation in the RB+ allele that leads to homozygosity for RB−. 
C) a somatic mutation in the RB− allele that leads to homozygosity for RB+. 
D) the fact that RB− is dominant to RB+.

Question 12

In Drosophila, singed bristles (sn)and carnation eyes (car)are both caused by recessive X-linked alleles.The wild-type alleles (snS1U1P1+S1S1P0 and carS1U1P1+S1S1P0)are responsible for straight bristles and red eyes, respectively.A sn car female is mated to a snS1U1P1+S1S1P0 carS1U1P1+S1S1P0 male and the FS1U1B11S1U1B0 progeny are interbred.The FS1U1B12S1U1B0 are distributed as follows:
 $$\begin{array} { | l | r | } 
\hline s n~ c a r & 55 \
\hline s n~ c a r^+ & 45\
\hline s n ^{+ c a r} & 45 \
\hline s n ^ { + c a r +}  & \underline{55} \
\hline & 200 \
\hline
\end{array}$$  
-What is the p value from this test? (Pick the most accurate choice. )

Accepted Answer

A) p > 0.5 B) 0.1 < p < 0.5 C) p < 0.1 D) p < 0.05 E) p < 0.01 A) p > 0.5 B) 0.1 < p < 0.5 C) p < 0.1 D) p < 0.05 E) p < 0.01

Question 13

The R and S genes are linked and 10 map units apart.In the cross R s / r S × r s / r s what fraction of the progeny will be R S / r s?

Accepted Answer

A) 5% 
B) 10% 
C) 25% 
D) 40% 
E) 45% 
A) 5% 
B) 10% 
C) 25% 
D) 40% 
E) 45%

Question 14

The R and S genes are linked and 10 map units apart.In the cross R s / r S × r s / r s what percentage of the progeny will be R s / r s?

Accepted Answer

A) 5% 
B) 10% 
C) 25% 
D) 40% 
E) 45% 
A) 5% 
B) 10% 
C) 25% 
D) 40% 
E) 45%

Question 15

The hypothesis that predicts no linkage between genes is known as the null hypothesis.

Accepted Answer

A) True 
 B)False

Question 16

In tetrad analysis, which result would indicate that two genes are linked?

Accepted Answer

A) NPD = T. 
B) PD = T. 
C) PD = NPD. 
D) PD > NPD. 
E) PD > T. 
A) NPD = T. 
B) PD = T. 
C) PD = NPD. 
D) PD > NPD. 
E) PD > T.

Question 17

The diploid garden pea plant has 14 chromosomes.The haploid fungus Neurospora crassa has 7 chromosomes.Neither organism has separate male and female individuals.Therefore, the number of linkage groups in these two organisms is

Accepted Answer

A) the garden pea has 14 linkage groups, and Neurospora has 7. 
B) the garden pea has 7 linkage groups, and Neurospora has 7. 
C) the garden pea has 8 linkage groups, and Neurospora has 8. 
D) the garden pea has 15 linkage groups, and Neurospora has 8. 
A) the garden pea has 14 linkage groups, and Neurospora has 7. 
B) the garden pea has 7 linkage groups, and Neurospora has 7. 
C) the garden pea has 8 linkage groups, and Neurospora has 8. 
D) the garden pea has 15 linkage groups, and Neurospora has 8.

Question 18

Which type of tetrad contains two recombinant and two parental spores?

Accepted Answer

A) PD 
B) NPD 
C) T 
D) ordered tetrads 
E) None of these types contain two recombinant and two parental spores. 
A) PD 
B) NPD 
C) T 
D) ordered tetrads 
E) None of these types contain two recombinant and two parental spores.

What does the data analysis allow you to conclude about linkage between sn and car? (Select all that apply. )

The map of a chromosome interval is: A--10 m.u.--B--40 m.u.--C From the cross A b c / a B C × a b c / a b c, how many double crossovers would be expected out of 1000 progeny?

The cross L p q / l P Q × l p q / l p q is carried out.If the L gene is in the middle, between genes P and Q, what would be the genotypes of the double crossover gametes in this cross?

Individuals heterozygous for the RB⁺ and RB⁻ alleles can develop tumors as a result of (Select all that apply. )

The R and S genes are linked and 10 map units apart.In the cross R s / r S × r s / r s what fraction of the progeny will be R S / r s?

The R and S genes are linked and 10 map units apart.In the cross R s / r S × r s / r s what percentage of the progeny will be R s / r s?

The hypothesis that predicts no linkage between genes is known as the null hypothesis.

In tetrad analysis, which result would indicate that two genes are linked?

The diploid garden pea plant has 14 chromosomes.The haploid fungus Neurospora crassa has 7 chromosomes.Neither organism has separate male and female individuals.Therefore, the number of linkage groups in these two organisms is

Which type of tetrad contains two recombinant and two parental spores?

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

DNA Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters

Exam 5: Linkage, Recombination, and the Mapping of Genes on Chromosomes

What does the data analysis allow you to conclude about linkage between sn and car? (Select all that apply. )

The map of a chromosome interval is: A--10 m.u.--B--40 m.u.--C From the cross A b c / a B C × a b c / a b c, how many double crossovers would be expected out of 1000 progeny?

The cross L p q / l P Q × l p q / l p q is carried out.If the L gene is in the middle, between genes P and Q, what would be the genotypes of the double crossover gametes in this cross?

Individuals heterozygous for the RB+ and RB− alleles can develop tumors as a result of (Select all that apply. )

The R and S genes are linked and 10 map units apart.In the cross R s / r S × r s / r s what fraction of the progeny will be R S / r s?

The R and S genes are linked and 10 map units apart.In the cross R s / r S × r s / r s what percentage of the progeny will be R s / r s?

The hypothesis that predicts no linkage between genes is known as the null hypothesis.

In tetrad analysis, which result would indicate that two genes are linked?

The diploid garden pea plant has 14 chromosomes.The haploid fungus Neurospora crassa has 7 chromosomes.Neither organism has separate male and female individuals.Therefore, the number of linkage groups in these two organisms is

Which type of tetrad contains two recombinant and two parental spores?

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

The Chromosome Theory of Inheritance

DNA Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters

Individuals heterozygous for the RB⁺ and RB⁻ alleles can develop tumors as a result of (Select all that apply. )