Question 1

You examine cells with a microscope and detect two Barr bodies in each cell.What is the most likely genotype of the cells?

Accepted Answer

A) XX 
B) XY 
C) XO 
D) XXY 
E) XXX 
A) XX 
B) XY 
C) XO 
D) XXY 
E) XXX

Question 2

Mitosis results in ________ chromosome number, whereas meiosis results in ________ chromosome number.

Accepted Answer

A) a doubling of; no change in 
B) no change in; no change in 
C) a reduction by half in; no change in 
D) no change in; a doubling of 
E) no change in; a reduction by half in 
A) a doubling of; no change in 
B) no change in; no change in 
C) a reduction by half in; no change in 
D) no change in; a doubling of 
E) no change in; a reduction by half in

Question 3

Males with one copy of an X-linked gene are said to be ________ for that gene.

Accepted Answer

A) homozygous 
B) heteroallelic 
C) heterozygous 
D) hemizygous 
E) deficient 
A) homozygous 
B) heteroallelic 
C) heterozygous 
D) hemizygous 
E) deficient

Question 4

Which aspect(s)of chromosome behavior is/are primarily responsible for the tremendous amount of genetic variability associated with sexual reproduction?

Accepted Answer

A) segregation of sister chromatids at anaphase II of meiosis 
B) segregation of homologous chromosomes at anaphase I of meiosis 
C) crossing-over between homologous chromosomes during prophase I of meiosis 
D) independent alignment of different homologous pairs on the metaphase I spindle 
E) both crossing-over between homologous chromosomes during prophase I of meiosis and independent alignment of different homologous pairs on the metaphase I spindle 
A) segregation of sister chromatids at anaphase II of meiosis 
B) segregation of homologous chromosomes at anaphase I of meiosis 
C) crossing-over between homologous chromosomes during prophase I of meiosis 
D) independent alignment of different homologous pairs on the metaphase I spindle 
E) both crossing-over between homologous chromosomes during prophase I of meiosis and independent alignment of different homologous pairs on the metaphase I spindle

Question 5

A cell with three pairs of chromosomes has the genotype Aa Bb Cc, with each locus on a different chromosome.If this cell were to undergo mitotic division, how many genetically different types of daughter cells could be produced?

Accepted Answer

A) 1 
B) 3 
C) 6 
D) 8 
E) 9 
A) 1 
B) 3 
C) 6 
D) 8 
E) 9

Question 6

Drosophila melanogaster has four pairs of chromosomes (including a pair of sex chromosomes).Sperm from this species are formed by a meiotic process in which homologous chromosomes pair and segregate but do not undergo crossing-over.How many genetically different kinds of sperm could be produced by a Drosophila melanogaster male (XY)?

Accepted Answer

A) 4 
B) 8 
C) 16 
D) 64 
E) 256 
A) 4 
B) 8 
C) 16 
D) 64 
E) 256

Question 7

In the following pedigree, the indicated trait is caused by what type of allele?

Accepted Answer

A) autosomal recessive 
B) autosomal dominant 
C) X-linked recessive 
D) X-linked dominant 
E) Y-linked 
A) autosomal recessive 
B) autosomal dominant 
C) X-linked recessive 
D) X-linked dominant 
E) Y-linked

Question 8

Cells in the G0 stage

Accepted Answer

A) have two chromatids per chromosome. 
B) are replicating their chromosomes. 
C) are about to enter the mitotic phase of the cell cycle. 
D) are in an extended G1 phase and no longer dividing. 
E) are dead. 
A) have two chromatids per chromosome. 
B) are replicating their chromosomes. 
C) are about to enter the mitotic phase of the cell cycle. 
D) are in an extended G1 phase and no longer dividing. 
E) are dead.

Question 9

You engineer an XY mouse in which the SRY gene is inactivated.What do you expect to observe in this mouse?

Accepted Answer

A) The mouse will develop male anatomic features. 
B) The mouse will develop female anatomic features. 
C) The mouse's Y chromosome will convert into an X chromosome. 
D) The mouse's X chromosome will convert into a Y chromosome. 
E) The mouse will exhibit both male and female morphological features. 
A) The mouse will develop male anatomic features. 
B) The mouse will develop female anatomic features. 
C) The mouse's Y chromosome will convert into an X chromosome. 
D) The mouse's X chromosome will convert into a Y chromosome. 
E) The mouse will exhibit both male and female morphological features.

Question 10

In fruit flies, an X-linked dominant mutant allele of the Notch gene (N)causes Notched wings in heterozygous females but is lethal in hemizygous or homozygous condition.What ratio of offspring would be observed in a cross of a Notched-wing female with a normal male?

Accepted Answer

A) 1/3 Notched-wing females, 1/3 normal females, 1/3 normal males 
B) 1/4 Notched-wing females, 1/4 normal females, 1/4 Notched-wing males, 1/4 normal males 
C) 1/2 Notched-wing females, 1/2 normal males 
D) 1/2 normal females, 1/2 Notched-wing males 
E) 2/3 Notched-wing females, 1/3 normal males 
A) 1/3 Notched-wing females, 1/3 normal females, 1/3 normal males 
B) 1/4 Notched-wing females, 1/4 normal females, 1/4 Notched-wing males, 1/4 normal males 
C) 1/2 Notched-wing females, 1/2 normal males 
D) 1/2 normal females, 1/2 Notched-wing males 
E) 2/3 Notched-wing females, 1/3 normal males

Question 11

Individuals with Turner syndrome have which of the following sex chromosome complements?

Accepted Answer

A) XO 
B) XX 
C) XYY 
D) XXY 
E) XXX 
A) XO 
B) XX 
C) XYY 
D) XXY 
E) XXX

Question 12

An XY individual with a loss-of-function mutation in the SRY gene is expected to be female.

Accepted Answer

A) True 
 B)False

Question 13

Suppose you discover a new species of worm that exists in two forms-slimy and nonslimy.You find that mating slimy females to nonslimy males produces offspring consisting of slimy males and nonslimy females, whereas mating nonslimy females with slimy males produces offspring of both sexes that are all slimy.You would conclude that the ________ allele is dominant and that ________ are the heterogametic sex (the sex with two different sex chromosomes)in this species of worm.

Accepted Answer

A) slimy; females 
B) slimy; males 
C) nonslimy; females 
D) nonslimy; males 
A) slimy; females 
B) slimy; males 
C) nonslimy; females 
D) nonslimy; males

Question 14

In human oogenesis, how many chromosomes does a primary oocyte carry?

Accepted Answer

A) 22 
B) 23 
C) 44 
D) 46 
E) 92 
A) 22 
B) 23 
C) 44 
D) 46 
E) 92

Question 15

During which of the following stages of the cell cycle would a chromosome consist of only a single chromatid?

Accepted Answer

A) G1 
B) G2 
C) mitotic prophase 
D) mitotic metaphase 
E) All of the choices are correct. 
A) G1 
B) G2 
C) mitotic prophase 
D) mitotic metaphase 
E) All of the choices are correct.

Question 16

In human oogenesis, how many chromosomes does a secondary oocyte carry?

Accepted Answer

A) 22 
B) 23 
C) 44 
D) 46 
E) 92 
A) 22 
B) 23 
C) 44 
D) 46 
E) 92

Question 17

What aspect of chromosome behavior most clearly accounts for Mendel's law of independent assortment?

Accepted Answer

A) movement of sister chromatids to opposite poles at anaphase II of meiosis 
B) movement of homologous chromosomes to opposite poles at anaphase I of meiosis 
C) crossing over between homologous chromosomes during prophase I of meiosis 
D) replication of chromosomes prior to meiosis 
E) independent alignment of different homologous pairs on the metaphase I spindle 
A) movement of sister chromatids to opposite poles at anaphase II of meiosis 
B) movement of homologous chromosomes to opposite poles at anaphase I of meiosis 
C) crossing over between homologous chromosomes during prophase I of meiosis 
D) replication of chromosomes prior to meiosis 
E) independent alignment of different homologous pairs on the metaphase I spindle

Question 18

The mitotic stage during which chromosomes begin attaching to spindle fibers and moving randomly and reversibly to the centrosomes is

Accepted Answer

A) prophase. 
B) prometaphase. 
C) metaphase. 
D) anaphase. 
E) telophase. 
A) prophase. 
B) prometaphase. 
C) metaphase. 
D) anaphase. 
E) telophase.

Question 19

Which of the following is not a property of homologous chromosomes?

Accepted Answer

A) They pair physically during prophase of meiosis I. 
B) They exchange genes by crossing over during meiosis. 
C) They carry alleles for the same genes at the same chromosomal position. 
D) Their centromeres are attached to each other during G2 of the cell cycle. 
E) They segregate to opposite poles at anaphase of meiosis I. 
A) They pair physically during prophase of meiosis I. 
B) They exchange genes by crossing over during meiosis. 
C) They carry alleles for the same genes at the same chromosomal position. 
D) Their centromeres are attached to each other during G2 of the cell cycle. 
E) They segregate to opposite poles at anaphase of meiosis I.

Question 20

In the following pedigree, the indicated trait most likely is caused by which type of allele?

Accepted Answer

A) autosomal recessive 
B) autosomal dominant 
C) X-linked recessive 
D) X-linked dominant 
E) Y-linked 
A) autosomal recessive 
B) autosomal dominant 
C) X-linked recessive 
D) X-linked dominant 
E) Y-linked

You examine cells with a microscope and detect two Barr bodies in each cell.What is the most likely genotype of the cells?

Mitosis results in chromosome number, whereas meiosis results in chromosome number.

Males with one copy of an X-linked gene are said to be ________ for that gene.

Which aspect(s)of chromosome behavior is/are primarily responsible for the tremendous amount of genetic variability associated with sexual reproduction?

A cell with three pairs of chromosomes has the genotype Aa Bb Cc, with each locus on a different chromosome.If this cell were to undergo mitotic division, how many genetically different types of daughter cells could be produced?

In the following pedigree, the indicated trait is caused by what type of allele?

Cells in the G₀ stage

You engineer an XY mouse in which the SRY gene is inactivated.What do you expect to observe in this mouse?

In fruit flies, an X-linked dominant mutant allele of the Notch gene (N)causes Notched wings in heterozygous females but is lethal in hemizygous or homozygous condition.What ratio of offspring would be observed in a cross of a Notched-wing female with a normal male?

Individuals with Turner syndrome have which of the following sex chromosome complements?

An XY individual with a loss-of-function mutation in the SRY gene is expected to be female.

In human oogenesis, how many chromosomes does a primary oocyte carry?

During which of the following stages of the cell cycle would a chromosome consist of only a single chromatid?

In human oogenesis, how many chromosomes does a secondary oocyte carry?

What aspect of chromosome behavior most clearly accounts for Mendel's law of independent assortment?

The mitotic stage during which chromosomes begin attaching to spindle fibers and moving randomly and reversibly to the centrosomes is

Which of the following is not a property of homologous chromosomes?

In the following pedigree, the indicated trait most likely is caused by which type of allele?

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters

Exam 4: The Chromosome Theory of Inheritance

You examine cells with a microscope and detect two Barr bodies in each cell.What is the most likely genotype of the cells?

Mitosis results in ________ chromosome number, whereas meiosis results in ________ chromosome number.

Males with one copy of an X-linked gene are said to be ________ for that gene.

Which aspect(s)of chromosome behavior is/are primarily responsible for the tremendous amount of genetic variability associated with sexual reproduction?

A cell with three pairs of chromosomes has the genotype Aa Bb Cc, with each locus on a different chromosome.If this cell were to undergo mitotic division, how many genetically different types of daughter cells could be produced?

In the following pedigree, the indicated trait is caused by what type of allele?

Cells in the G0 stage

You engineer an XY mouse in which the SRY gene is inactivated.What do you expect to observe in this mouse?

In fruit flies, an X-linked dominant mutant allele of the Notch gene (N)causes Notched wings in heterozygous females but is lethal in hemizygous or homozygous condition.What ratio of offspring would be observed in a cross of a Notched-wing female with a normal male?

Individuals with Turner syndrome have which of the following sex chromosome complements?

An XY individual with a loss-of-function mutation in the SRY gene is expected to be female.

In human oogenesis, how many chromosomes does a primary oocyte carry?

During which of the following stages of the cell cycle would a chromosome consist of only a single chromatid?

In human oogenesis, how many chromosomes does a secondary oocyte carry?

What aspect of chromosome behavior most clearly accounts for Mendel's law of independent assortment?

The mitotic stage during which chromosomes begin attaching to spindle fibers and moving randomly and reversibly to the centrosomes is

Which of the following is not a property of homologous chromosomes?

In the following pedigree, the indicated trait most likely is caused by which type of allele?

Genetics: the Study of Biological Information

Mendels Principles of Heredity

Extensions to Mendels Laws

Linkage, Recombination, and the Mapping of Genes on Chromosomes

DNA Structure, Replication, and Recombination

Anatomy and Function of a Gene: Dissection Through Mutation

Gene Expression: the Flow of Information From Dna to Rna to Protein

Digital Analysis of Dna

Genome Annotation

Analyzing Genomic Variation

The Eukaryotic Chromosome

Chromosomal Rearrangements and Changes in Chromosome Number

Bacterial Genetics

Organellar Inheritance

Gene Regulation in Prokaryotes

Gene Regulation in Eukaryotes

Manipulating the Genomes of Eukaryotes

The Genetic Analysis of Development

The Genetics of Cancer

Variation and Selection in Populations

The Genetics of Complex Traits

Filters

Mitosis results in chromosome number, whereas meiosis results in chromosome number.

Cells in the G₀ stage