Exam 3: The Chromosome Theory of Inheritance

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Chiasmata are structures of cross over between non-sister chromatids of homologous chromosomes.

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In an individual with genotype Lpq/lPQ the L gene is in the middle.What would be the genotypes of the gametes produced by a double crossover surrounding the L locus?

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Some of the larger human chromosomes typically contain multiple chiasmata during meiotic prophase.If you were to carefully study the distribution of these chiasmata,what would you find?

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When mapping three genes,why do geneticists prefer to do one three-point cross rather than three two-point crosses? Give two reasons.

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Which of the following processes can generate recombinant gametes?

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How does Mendel's law of independent assortment relate to the concept of linkage?

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The map of a chromosome interval is Q-10 m.u.-R-40 m.u.-S.Which interval would likely show the higher ratio of double to single chiasmata?

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Genetic mapping distance calculated for a chromosome is directly related to physical distance along that chromosome.

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What are chiasmata?

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Individuals heterozygous for the RB+ and RB- alleles can develop tumours as a result of

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In peas,tall (T)is dominant to short (t),red flowers (R)is dominant to white flowers (r),and wide leaves (W)is dominant to narrow leaves (w).A tall,red,wide-leaved plant is crossed to a short,white,narrow-leaved plant and the progeny are as follows: tall red wide 381 tall white wide 122 short red wide 118 short white wide 379 1000 What is the genotype of the tall,red,wide-leaved parent?

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The measured distance between genes D and E in a two-point test cross is 50 map units.What does this mean in physical terms?

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Recombination due to crossing over occurs only rarely in mitosis.

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The R/r and S/s genes are linked and 10 map units apart.In the cross Rs/rS × rs/rs what fraction of the progeny will be RS/rs?

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The zipper-like connection between paired homologs in early prophase is known as a

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In Drosophila,the genes y,f,and v are all X-linked.y f v females are crossed to wild-type males and the F1 females are test-crossed.The F2 are distributed as follows. yfv 3210 yf+ 72 y+v 1024 y++ 678 +fv 690 +f+ 1044 ++v 60 +++ 10,000 State what a coefficient of coincidence of 0.5 would mean.

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In Drosophila,the genes y (yellow body)and car (carnation eyes)are located at opposite ends of the X chromosome.In doubly heterozygous females (y+ car+/y car),a single chiasma is observed somewhere along the X chromosome in 90% of the examined oocytes.No X chromosomes with multiple chiasmata are observed.What percentage of the male progeny from such a female would be recombinant for y and car?

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If the map distance between genes A and B is 10 map units and the map distance between genes B and C is 25 map units,what is the map distance between genes A and C?

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In fruit flies,the recessive pr and cn mutations cause brown and bright-red eyes,respectively (wild-type flies have brick-red eyes).The double mutant pr cn combination has orange eyes.A female who has wild-type eyes is crossed to an orange-eyed male.Their progeny have the following distribution of eye colours: wild-type 8 brown 241 bright-red 239 orange 12 500 Which classes are the parental types?

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Suppose the L and M genes are on the same chromosome but separated by 100 map units.What fraction of the progeny from the cross LM/lm × lm/lm would be Lm/lm?

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