Exam 10: Analyzing Genomic Variation

A cis-acting DNA sequence that modulates the basal rate of transcription of a gene is termed a(n)

Which of the following would be suggested by a DNase hypersensitive site?

You have cloned and sequenced a new mouse gene and wish to know whether chromatin structure may affect its transcription.You DNase treat and then run Southern analysis.In the mouse strain with hypothetical phenotype A you detect your gene,but it is not detected in DNase treated samples from the mouse strain with phenotype B.What do you suspect as the cause?

In Drosophila females,Sxl protein associates with RNA transcribed from the ________________ gene,altering its splicing pattern.

In generating a reporter construct to study gene regulation,the reporter gene introduced replaces

Mutations in the GAL80 gene in yeast result in the continuous expression of the GAL1,GAL7,and GAL10 genes,even in the absence of galactose.This genetic evidence suggests that the GAL80 gene product acts as a(n)

The Myc protein is synthesized only in cells that are

tRNA molecules are transcribed by

Enhancers are regulatory sites that are next to the promoter.

Basal transcription factors bind to the promoters of all protein-encoding genes.

Hypercondensation of heterochromatin results in

Regions of DNA are most sensitive to DNase digestion when

The gene products encoded by trans-acting elements perform their function by

A variation that does not involve a change in DNA sequence but can be passed from one generation to another is a(n)

RNA interference is a process that regulates gene expression at the time of transcription.

The __________________________ is the cis-acting DNA sequence that serves as the binding site for RNA polymerase.

Reporter constructs are used to identify and characterize DNA sequences that regulate the expression levels of specific genes.What two DNA sequences are linked together to generate a reporter construct?

DNA regions that are transcriptionally silenced by hypercondensation have often undergone a modification of their cytosine residues termed

Most decisions controlling the amount of gene product synthesized are made during

The max gene is expressed at all times.