Exam 14: Regulation of Gene Expression in Eukaryotes

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Before Muller's discovery that radiation induces mutation, scientists had to work on spontaneous mutants that were found solely by phenotype differences in natural populations. Which of the features of Drosophila made it a fortuitous choice for Morgan and his colleagues?

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A single nucleotide in a genome can be targeted for mutagenesis using the__________ technique, adapted from a bacterial defense system.

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In nature, RNAi protects cells against infection by what kind of pathogen?

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DNA markers that are found to segregate with a mutation of interest can be used to determine the mutation's distance from the markers by looking at what?

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