Exam 10: Chromosome Exam Title Tbd

A chromosome has broken, and a piece of one chromosome is translocated to a non- homologous chromosome. This is an example of what type of chromosomal alteration?

"Seedless" fruits and vegetables have how many chromosomes and what type of chromosomal distribution?

Histone proteins are the principal agents in chromatin packaging. The nucleosome core particle is a heterooctam protein complex that contains two molecules each of the four histones H2A, H2B, H3, and H4. Describe the proce managing existing nucleosome core particles during replication and the process of adding these and new nucleo core particles to DNA after the replication fork passes.

When nondisjunction occurs early in embryogenesis rather than gametogenesis, what would you expect in the resulting karyotype?

A region of a chromosome spanning the centromere is broken and reattached in the reverse direction. This is an example of which type of chromosomal defect?

Which of the following correctly lists the levels of compaction in eukaryotes from naked DNA to the most compact?

Which of the following is true regarding heterozygous carriers of large chromosome inversions or translocations?

The phenomenon of _____________ in allopolyploids consists of more rapid growth, increased fruit and flower production, and improved disease resistance.

There is clear evidence that chromatin state is directly related to the ability of transcriptionally active proteins to initiate gene transcription. Compare and contrast euchromatin to heterochromatin in the context of transcription.

Which type of chromosome deletion is caused by two concurrent chromosome breaks (rather than a single break)?

You are attempting to isolate cells for your karyotype, and you find one cell in each of the phases (prophase, metaphase, anaphase, and telophase). Which one is best suited for a karyotype?

What are the two common patterns of chromosome segregation seen in the tetravalent structures found in translocation heterozygotes?

Which histone protein is not part of the core nucleosome structure?

Donkeys have a somatic chromosome number of 62. Hybrids produced by crossing donkeys and zebras are called zonkeys, are sterile, and have many characteristics intermediate between the two parental species. If a zonkey has 52 chromosomes, what is the somatic chromosome number of zebras?

After DNA replication, during reassembly of nucleosomes, the________tetramers are bound by H2A- H2B dimers to form complete nucleosomes.

Cri- du- chat syndrome is a human disorder caused by which type of chromosomal defect?

A karyotype shows that a child has Klinefelter syndrome (47,XXY). If the child is also color- blind (due to a recessive X- linked allele), despite his parents having normal color vision, in which parent and stage of meiosis did nondisjunction occur?

How is aneuploidy different from polyploidy? What are the mechanisms by which aneuploidy and polyploidy are caused, and what are the consequences of these chromosomal alterations in terms of survival and fertility of the offspring?

If nondisjunction occurs in meiosis I of a mother, what proportion of her gametes could have been fertilized by a normal sperm to produce a child with Turner syndrome?

Which proteins would you target if you wanted to disrupt the chromosome superstructure for chromatin condensation that ultimately produces the characteristic shape of the metaphase chromosome?