Question 1

The opening of NMDA receptor channels require synaptic depolarization.

Accepted Answer

A) True 
 B)False  True

Question 2

What are the two conditions that must be met for Ca2+ ions to flow into the neuron?

Accepted Answer

1) ligand binding (glutamate); 2) synaptic depolarization

Question 3

Which statement(s) about LTP is/are false? (Select all that apply.)

Accepted Answer

A)  NMDA and AMPA receptors are required for the induction of LTP. 
B)  CNQX can inhibit induction, but not expression, of LTP. 
C)  APV can inhibit induction, but not expression, of LTP. 
D)  To express LTP, NMDA and AMPA channels are crucial. 
E)  None of the above 
A)  NMDA and AMPA receptors are required for the induction of LTP. 
B)  CNQX can inhibit induction, but not expression, of LTP. 
C)  APV can inhibit induction, but not expression, of LTP. 
D)  To express LTP, NMDA and AMPA channels are crucial. 
E)  None of the above B,D

Question 4

What is APV, and what is its function?

Accepted Answer

The answer of What is APV, and what is its...

Question 5

Why should inhibiting AMPA receptors prevent the expression of LTP?

Accepted Answer

The answer of Why should inhibiting AMPA receptors prevent the...

Question 6

Why should inhibiting NMDA receptors prevent the degradation of the actin cytoskeleton?

Accepted Answer

The answer of Why should inhibiting NMDA receptors prevent the...

Question 7

AMPA receptors influx mainly Na+; NMDA receptors influx both Na+ and Ca2+.

Accepted Answer

A) True 
 B)False

Question 8

The degradation of the actin cytoskeleton depends on spectrins degrading calpains.

Accepted Answer

A) True 
 B)False

Question 9

Phosphatases add phosphates to other proteins.

Accepted Answer

A) True 
 B)False

Question 10

Glutamate is an excitatory neurotransmitter.

Accepted Answer

A) True 
 B)False

Question 11

The delivery of AMPA receptors produced by LTP induction involves both lateral diffusion and the exocytic processes.

Accepted Answer

A) True 
 B)False

Question 12

AMPA trafficking is regulated _______ and by _______.

Accepted Answer

The answer of AMPA trafficking is regulated _______ and by...

Question 13

Glutamate receptors involved in LTP are found along the axon.

Accepted Answer

A) True 
 B)False

Question 14

Competitive antagonists, such as APV, can replace a ligand and cause conformational changes in the receptor.

Accepted Answer

A) True 
 B)False

Question 15

Which term(s) applies/apply to glutamate? (Select all that apply.)

Accepted Answer

A)  Neurotransmitter 
B)  First messenger 
C)  Ligand 
D)  Receptor 
E)  None of the above. 
A)  Neurotransmitter 
B)  First messenger 
C)  Ligand 
D)  Receptor 
E)  None of the above.

Question 16

Why would an increase in the population of AMPA receptors increase the fEPSP?

Accepted Answer

The answer of Why would an increase in the population...

Question 17

Stargazin is critical to the trapping of AMPA receptors in the PSD.

Accepted Answer

A) True 
 B)False

Question 18

You could block the expression of LTP by inhibiting _______ receptors.

Accepted Answer

The answer of You could block the expression of LTP...

Question 19

Which is/are shared by NMDA and AMPA receptors? (Select all that apply.)

Accepted Answer

A)  Neither bind to glutamate. 
B)  Both have a magnesia binding site. 
C)  Both require depolarizing in order to open the channel. 
D)  Both are voltage gated. 
E)  None of the above. 
A)  Neither bind to glutamate. 
B)  Both have a magnesia binding site. 
C)  Both require depolarizing in order to open the channel. 
D)  Both are voltage gated. 
E)  None of the above.

Question 20

What is an excitatory synapse?

Accepted Answer

The answer of What is an excitatory synapse?...

The opening of NMDA receptor channels require synaptic depolarization.

What are the two conditions that must be met for Ca²⁺ ions to flow into the neuron?

Which statement(s) about LTP is/are false? (Select all that apply.)

What is APV, and what is its function?

Why should inhibiting AMPA receptors prevent the expression of LTP?

Why should inhibiting NMDA receptors prevent the degradation of the actin cytoskeleton?

AMPA receptors influx mainly Na⁺; NMDA receptors influx both Na⁺ and Ca²⁺.

The degradation of the actin cytoskeleton depends on spectrins degrading calpains.

Phosphatases add phosphates to other proteins.

Glutamate is an excitatory neurotransmitter.

The delivery of AMPA receptors produced by LTP induction involves both lateral diffusion and the exocytic processes.

AMPA trafficking is regulated _ and by _.

Glutamate receptors involved in LTP are found along the axon.

Competitive antagonists, such as APV, can replace a ligand and cause conformational changes in the receptor.

Which term(s) applies/apply to glutamate? (Select all that apply.)

Why would an increase in the population of AMPA receptors increase the fEPSP?

Stargazin is critical to the trapping of AMPA receptors in the PSD.

You could block the expression of LTP by inhibiting _______ receptors.

Which is/are shared by NMDA and AMPA receptors? (Select all that apply.)

What is an excitatory synapse?

Introduction: Fundamental Concepts and Historical Foundations

Memory and the Brain: Central Concepts

Stabilizing Long-Term Potentiation

Consolidating Ltp: Translation and Transcription

Consolidating Ltp: Specific Mechanisms

Maintaining Long-Term Potentiation

Bringing It All Together

Making Memories: Conceptual Issues and Methodologies

Memory Formation: Early Stages

Memory Consolidation

Memory Modulation Systems

The Yin and Yang of Memory: Forgetting Versus Maintenance

Hunting for Engrams

The Fate of Retrieved Memories

Memory Systems and the Hippocampus

The Hippocampus Index and Episodic Memory

When Memories Age

Actions, Habits, and the Cortico-Striatal System

Learning About Danger: the Neurobiology of Fear Memories

Filters

Exam 3: Generating Long-Term Potentiation

The opening of NMDA receptor channels require synaptic depolarization.

What are the two conditions that must be met for Ca2+ ions to flow into the neuron?

Which statement(s) about LTP is/are false? (Select all that apply.)

What is APV, and what is its function?

Why should inhibiting AMPA receptors prevent the expression of LTP?

Why should inhibiting NMDA receptors prevent the degradation of the actin cytoskeleton?

AMPA receptors influx mainly Na+; NMDA receptors influx both Na+ and Ca2+.

The degradation of the actin cytoskeleton depends on spectrins degrading calpains.

Phosphatases add phosphates to other proteins.

Glutamate is an excitatory neurotransmitter.

The delivery of AMPA receptors produced by LTP induction involves both lateral diffusion and the exocytic processes.

AMPA trafficking is regulated _______ and by _______.

Glutamate receptors involved in LTP are found along the axon.

Competitive antagonists, such as APV, can replace a ligand and cause conformational changes in the receptor.

Which term(s) applies/apply to glutamate? (Select all that apply.)

Why would an increase in the population of AMPA receptors increase the fEPSP?

Stargazin is critical to the trapping of AMPA receptors in the PSD.

You could block the expression of LTP by inhibiting _______ receptors.

Which is/are shared by NMDA and AMPA receptors? (Select all that apply.)

What is an excitatory synapse?

Introduction: Fundamental Concepts and Historical Foundations

Memory and the Brain: Central Concepts

Stabilizing Long-Term Potentiation

Consolidating Ltp: Translation and Transcription

Consolidating Ltp: Specific Mechanisms

Maintaining Long-Term Potentiation

Bringing It All Together

Making Memories: Conceptual Issues and Methodologies

Memory Formation: Early Stages

Memory Consolidation

Memory Modulation Systems

The Yin and Yang of Memory: Forgetting Versus Maintenance

Hunting for Engrams

The Fate of Retrieved Memories

Memory Systems and the Hippocampus

The Hippocampus Index and Episodic Memory

When Memories Age

Actions, Habits, and the Cortico-Striatal System

Learning About Danger: the Neurobiology of Fear Memories

Filters

What are the two conditions that must be met for Ca²⁺ ions to flow into the neuron?

AMPA receptors influx mainly Na⁺; NMDA receptors influx both Na⁺ and Ca²⁺.

AMPA trafficking is regulated _ and by _.