Exam 13: The Yin and Yang of Memory: Forgetting Versus Maintenance

Inhibiting NMDA receptor function during the retention interval enhances the rate of forgetting.

From the psychological perspective, all forgetting is a consequence of intrinsic neural processes that degrade synapses.

_______ trace theory asserts that forgetting is retrieval failure that is due to competition among similar memory traces for expression.

Stress produced by social isolation increases the rate of forgetting because it puts Rac1 in the inactive state.

ZIP will erase taste-aversion memories only if injected at a specific time after acquisition.

Neurobiologist assume that all forgetting is due to a retrieval failure.

Enhancing NMDA function during the retention interval prevents forgetting, whereas inhibiting NMDA function accelerates forgetting.

By interfering with AMPA receptor endocytosis, PKMζ can prevent forgetting.

Enhancing NMDA function during the retention interval accelerates forgetting, whereas inhibiting NMDA function prevents forgetting.

Dudai used two strategies to assess the role of PKMζ in preventing forgetting. What were they?

In its active state the GTPase Rac1 often leads to rapid forgetting. If Rac1 is inactive, however, the rate of forgetting is markedly slower.

Imagine a drug that inhibited the activity of Rac1. What effect should this drug have on forgetting?

A retrieval failure can be the result of two similar memories competing for expression.

The peptide _______ prevents forgetting.

The dominate negative PKMζ construct enhances forgetting because it is highly active.

There are intrinsic forces operating to degrade the synaptic basis of memories.

Enhancing NMDA function during the retention interval enhances forgetting whereas inhibiting NMDA function accelerates forgetting.

By interfering with NMDA receptor function, PKMζ can prevent forgetting.

The peptide GluR23y inhibits the removal AMPA receptors from the PSD.

Which statement(s) is/are true? (Select all that apply.)