Question 1

The evaluation of HER2/neu has what clinical function?

Accepted Answer

A)  Diagnostic marker 
B)  Predictive marker for response to herceptin 
C)  Prognostic marker in breast cancer 
D)  Both b and c 
A)  Diagnostic marker 
B)  Predictive marker for response to herceptin 
C)  Prognostic marker in breast cancer 
D)  Both b and c D

Question 2

A new positive prognostic indicator for primary breast cancer in women is:

Accepted Answer

A)  a good gene expression signature. 
B)  a low S phase tumor cell content. 
C)  diploid DNA content of tumor cells. 
D)  all of the above. 
A)  a good gene expression signature. 
B)  a low S phase tumor cell content. 
C)  diploid DNA content of tumor cells. 
D)  all of the above. A

Question 3

Most tumors are of connective tissue origin.

Accepted Answer

A) True 
 B)False  False

Question 4

Cancer results from a series of genetic alterations that can include affecting a host's ability to repair resulting damage to DNA.

Accepted Answer

A) True 
 B)False

Question 5

MATCHING
Match the characteristics with the type of tumor.

-Minimal mitotic activity

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant

Question 6

Match the following.Chemotherapeutic agents are placed into various classes of drug action:

-Act on the S,G2,or M phase of mitosis

Accepted Answer

A) Cell cycle active,phase-specific 
B) Cell cycle active,phase-nonspecific 
C) Non-cell cycle active 
A) Cell cycle active,phase-specific 
B) Cell cycle active,phase-nonspecific 
C) Non-cell cycle active

Question 7

Match the antigens with the appropriate description.

-Tumor-associated antigens

Accepted Answer

A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism 
A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism

Question 8

The most common cause of pediatric cancer deaths is:

Accepted Answer

A)  acute lymphoblastic leukemia. 
B)  tumors of the central and sympathetic nervous system. 
C)  malignant lymphoma. 
D)  renal tumors. 
A)  acute lymphoblastic leukemia. 
B)  tumors of the central and sympathetic nervous system. 
C)  malignant lymphoma. 
D)  renal tumors.

Question 9

MATCHING
Match the characteristics with the type of tumor.

-Metastasis

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant

Question 10

A cancer-disposing gene,BRCA2,is associated with a very high risk of:

Accepted Answer

A)  uterine cancer. 
B)  endometrial cancer. 
C)  breast cancer. 
D)  none of the above. 
A)  uterine cancer. 
B)  endometrial cancer. 
C)  breast cancer. 
D)  none of the above.

Question 11

MATCHING
Match the characteristics with the type of tumor.

-Resembling the parent tissue

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant

Question 12

Tumor immunity has the following general feature-the normal immune response frequently prevents the growth of tumors.

Accepted Answer

A) True 
 B)False

Question 13

Tumor immunity has the following general feature-the immune system can be stimulated to kill tumor cells and rid the host of the tumor.

Accepted Answer

A) True 
 B)False

Question 14

MATCHING
Match the characteristics with the type of tumor.

-Increase in number of cells that accumulate

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant

Question 15

Tumor immunity has the following general feature-tumors express antigens that are recognized as foreign by the immune system of the tumor-bearing host.

Accepted Answer

A) True 
 B)False

Question 16

The term tumor is commonly used to describe a proliferation of cells that produces a(n):

Accepted Answer

A)  mass. 
B)  inflammatory condition. 
C)  reaction. 
D)  either b or c 
A)  mass. 
B)  inflammatory condition. 
C)  reaction. 
D)  either b or c

Question 17

Match the antigens with the appropriate description.

-Tumor-specific antigens

Accepted Answer

A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism 
A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism

Question 18

MATCHING
Match the characteristics with the type of tumor.

-Usually encapsulated

Accepted Answer

A) Benign 
B) Malignant 
A) Benign 
B) Malignant

Question 19

Tumors can be described as benign or malignant.

Accepted Answer

A) True 
 B)False

Question 20

Match the antigens with the appropriate description.

-Carcinofetal antigens

Accepted Answer

A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism 
A) Cell surface molecules coded for by tumorigenic viruses 
B) Gene derepression responsible for the production of increased concentrations of these gene products 
C) Chemically induced tumors 
D) Caused by no known mechanism

Exam 33: Tumor Immunology

The evaluation of HER2/neu has what clinical function?

A new positive prognostic indicator for primary breast cancer in women is:

Most tumors are of connective tissue origin.

Cancer results from a series of genetic alterations that can include affecting a host's ability to repair resulting damage to DNA.

MATCHING Match the characteristics with the type of tumor. -Minimal mitotic activity

Match the following.Chemotherapeutic agents are placed into various classes of drug action: -Act on the S,G2,or M phase of mitosis

Match the antigens with the appropriate description. -Tumor-associated antigens

The most common cause of pediatric cancer deaths is:

MATCHING Match the characteristics with the type of tumor. -Metastasis

A cancer-disposing gene,BRCA2,is associated with a very high risk of:

MATCHING Match the characteristics with the type of tumor. -Resembling the parent tissue

Tumor immunity has the following general feature-the normal immune response frequently prevents the growth of tumors.

Tumor immunity has the following general feature-the immune system can be stimulated to kill tumor cells and rid the host of the tumor.

MATCHING Match the characteristics with the type of tumor. -Increase in number of cells that accumulate

Tumor immunity has the following general feature-tumors express antigens that are recognized as foreign by the immune system of the tumor-bearing host.

The term tumor is commonly used to describe a proliferation of cells that produces a(n):

Match the antigens with the appropriate description. -Tumor-specific antigens

MATCHING Match the characteristics with the type of tumor. -Usually encapsulated

Tumors can be described as benign or malignant.

Match the antigens with the appropriate description. -Carcinofetal antigens

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Point-Of-Care Testing

Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Automated Procedures

Molecular Techniques

The Immune Response in Infectious Diseases

A Primer on Vaccines

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Acquired Immunodeficiency Syndrome

Hypersensitivity Reactions

Immunoproliferative Disorders

Autoimmune Disorders

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Solid Organ Transplantation

Bone Marrow Transplantation

Filters