Exam 19: Lipid Metabolism Ii: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids

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The enzyme PGH synthase contains two different functionalities, a that uses two molecules of oxygen as substrates and which performs a 2 electron reduction.

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Question 1

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7-dehydrocholesterol reacts with _________ to produce cholecalciferol (vitamin D₃)

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Question 2

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In prokaryotes, _ is used exclusively as the precursor for phosphatidic acid while in eukaryotes, _is one of three possible precursors.

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Question 3

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Which of the following is accomplished in one enzyme catalyzed reaction?

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Question 4

The synthesis of which of the following molecules would be inhibited by aspirin?

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Question 5

Which of the following amino acids is critical for choline and phosphatidylcholine synthesis?

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Question 6

In eukaryotes, the conversion of DHAP to 1-acylglycerol-3-phosphate is a two-step process. Show the reactants and products missing in the following scheme.

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Question 7

Show the products of the following reaction and name them:

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Question 8

Which of the following is used to activate phosphatidic acid for conversion to various phospholipids?

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Question 9

The synthesis of 1 molecule of cholesterol requires _ molecules of isopentenyl pyrophosphate, with each molecule of isopentenyl pyrophosphate requiring _ molecules of acetyl-CoA.

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Question 10

What is the term for the molecule shown below?

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Question 11

Which of the following explains why the bile acids are much better suited than cholesterol for use as emulsification agents for fats?

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Question 12

Which of the following is the regulatory step in cholesterol synthesis?

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Question 13

What classification is given to the following molecule?

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Question 14

The synthesis of the glycosphingolipids begins with the reaction of either UDP-glucose or UDP-galactose with _____________.

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Question 15

Tay-Sachs disease is caused by a deficiency of which results in an accumulation of _.

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Question 16

Which of the following forms of vitamin A is covalently attached to a lysine residue of the protein opsin to form the complex called rhodopsin?

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Question 17

How is the activity of HMG-CoA reductase reduced?

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Question 18

The synthesis of phosphatidylethanolamine in prokaryotes involves ___ while in mammals _ occurs.

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Question 19

Which of the following phospholipids is produced in eukaryotes but not prokaryotes?

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Question 20

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Exam 19: Lipid Metabolism Ii: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids

The enzyme PGH synthase contains two different functionalities, a __________ that uses two molecules of oxygen as substrates and __________ which performs a 2 electron reduction.

7-dehydrocholesterol reacts with _________ to produce cholecalciferol (vitamin D3)

In prokaryotes, _________ is used exclusively as the precursor for phosphatidic acid while in eukaryotes, _________is one of three possible precursors.

Which of the following is accomplished in one enzyme catalyzed reaction?

The synthesis of which of the following molecules would be inhibited by aspirin?

Which of the following amino acids is critical for choline and phosphatidylcholine synthesis?

In eukaryotes, the conversion of DHAP to 1-acylglycerol-3-phosphate is a two-step process. Show the reactants and products missing in the following scheme.

Show the products of the following reaction and name them:

Which of the following is used to activate phosphatidic acid for conversion to various phospholipids?

The synthesis of 1 molecule of cholesterol requires _____ molecules of isopentenyl pyrophosphate, with each molecule of isopentenyl pyrophosphate requiring _____ molecules of acetyl-CoA.

What is the term for the molecule shown below?

Which of the following explains why the bile acids are much better suited than cholesterol for use as emulsification agents for fats?

Which of the following is the regulatory step in cholesterol synthesis?

What classification is given to the following molecule?

The synthesis of the glycosphingolipids begins with the reaction of either UDP-glucose or UDP-galactose with _____________.

Tay-Sachs disease is caused by a deficiency of __________ which results in an accumulation of ___________.

Which of the following forms of vitamin A is covalently attached to a lysine residue of the protein opsin to form the complex called rhodopsin?

How is the activity of HMG-CoA reductase reduced?

The synthesis of phosphatidylethanolamine in prokaryotes involves _________________ while in mammals _______________ occurs.

Which of the following phospholipids is produced in eukaryotes but not prokaryotes?

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Nucleic Acids

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars, Saccharides, Glycans

Lipids, Membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, Utilization, and Turnover

Metabolism of Nitogenous Compounds II: Amino Acids, Porphyrins, and Neurotransmitters

Nucleotide Metabolism

Mechanisms of Signal Transduction

Genes, Genomes and Chromosomes

DNA Replication

DNA Restructuring: Repair, Recombination, Rearrangement, Amplification

Information Readout: Transcription and Post-Transcriptional Processing

Information Decoding: Translation and Post-Translational Protein Processing

Regulation of Gene Expression

Filters

The enzyme PGH synthase contains two different functionalities, a that uses two molecules of oxygen as substrates and which performs a 2 electron reduction.

7-dehydrocholesterol reacts with _________ to produce cholecalciferol (vitamin D₃)

In prokaryotes, _ is used exclusively as the precursor for phosphatidic acid while in eukaryotes, _is one of three possible precursors.

The synthesis of 1 molecule of cholesterol requires _ molecules of isopentenyl pyrophosphate, with each molecule of isopentenyl pyrophosphate requiring _ molecules of acetyl-CoA.

Tay-Sachs disease is caused by a deficiency of which results in an accumulation of _.

The synthesis of phosphatidylethanolamine in prokaryotes involves ___ while in mammals _ occurs.