Exam 29: Regulation of Gene Expression

Give the sequence and draw the first two residues of a morpholino oligo that would serve as an antisense RNA for the following mRNA sequence (you may use the letter A, C, G and U to denote the bases): 5'-CAUGUCC-3'

DNA methylation in eukaryotes plays a role in ____________.

At the transcriptional level, how does tryptophan control the production of genes within the trp operon?

When bacteriophage $\lambda$ lysogeny terminates and lytic growth in E. coli cells begins, ____ is inactivated leading to unoccupied O_R sites. _____ is produced, ultimately resulting in DNA replication.

What is thought to occur when CRP binds to DNA?

In a histone protein, what modification to lysine marks the nucleosome as a transcription target?

The phosphorylation of several RNA polymerase II serine residues has been identified as a key event in eukaryotic translation initiation. Which of the following is one of the enzymes responsible for this phosphorylation?

On the polycistronic mRNA of bacteriophage MS2, the ability to translate multiple copies of the coat protein but only a single copy of the A protein is accomplished by _________.

A short RNA that is complimentary to a specific mRNA and used for inhibition of translation is called ______________.

Which of the genes in the SOS regulon encodes a DNA polymerase?

If both lactose and glucose are present in large amounts, which of the following scenarios would result?

DNA damage that requires RecA to bind to a DNA gap activates proteolysis of _____, which then activates the transcription of genes within the SOS regulon.

An mRNA whose translation is controlled by binding of a metabolic end product such as flavin adenine dinucleotide or adenosylcobalamin is called a____________.

Which of the following bacteriophage $\lambda$ proteins serves as both an activator and a repressor?

Which of the following accounts for the greater complexity in eukaryotic transcriptional control when compared with prokaryotic control?

Design an antisense RNA that prevents the start of translation for any mRNA in an E. coli cell.

What elements are contained within the promoter of the lactose operon?

Lysine methylation in a histone protein produces a form of chromatin known as ________ with the genes being transcriptionally __________.

Bacteriophage $\lambda$ establishment of lysogeny in E. coli cells requires a high concentration of _____. This is achieved by the ____ protein binding to the P_RE regulatory site.

The bromodomain of nucleosome remodeling complexes binds to ____________ histones while the chromodomain binds to ___________ histones.