Exam 12: Control of Gene Expression

Which level of control of gene expression is defined as determining if a particular gene can give rise to mRNA and,if so,how often?

Mechanisms have been discovered that regulate the rate of mRNA translation in response to changing cellular requirements; these mechanism can act at both the ______ and ______ levels.

To which nucleotide base are methyl groups added during the process of DNA methylation?

What is used to maintain the Ran-GTP gradient across the nuclear envelope?

What strategy in transcription factor research allows the simultaneous monitoring of all sites in the genome that carry out a particular activity with the goal of identifying all of the sites bound by a given transcription factor under a given set of physiological conditions?

The glucocorticoid receptor functions as both a hormone receptor and a transcription factor.How are these functions connected to the protein's location in the cell?

What is the name of the linkage than holds the lactose disaccharide together?

The oskar protein is required for the ________,which develop at the _______ end of the larva.

What domain of a transcription factor is responsible for recognizing and associating with specific DNA base pair sequences?

Scientists often stain chromosomes from mitotic cells and photograph the chromosomes in the microscope.Each chromosome is cut out of the photograph,the chromosomes are matched up in homologous pairs and they are placed in order of decreasing size.These pictures can be used to screen individuals for chromosomal abnormalities,like extra,missing or grossly altered chromosomes.What is such a picture called?

To what is the NLS - protein cargo - importing $\alpha$ / $\beta$ complex thought to bind when it seems to dock to the outer surface of the nucleus near the nuclear pore complex?

Which of the following would be the most acceptable explanation for why cloned animals actually have telomeres of normal length on their chromosomes?

Which type of molecule binds at the core promoter sites in association with RNA polymerase?

What is the normal length of a poly(A)tail?

What site on a bacterial operon segment of a chromosome is adjacent to or overlaps with a promoter?

You are interpreting data on a DNA chip or microarray.You expose the chip to a mixture of two cDNA populations: one from cells that were not treated with a glucocorticoid hormone (untreated controls; labeled with a red fluorescent dye)and a population from cells that were treated with glucocorticoid hormones (glucocorticoid-treated; labeled with green fluorescent dye).You look at a spot on the chip representing the gene for phosphofructokinase,a gene that is not affected by glucocorticoid treatment,but is instead expressed in all cells.What color should the spot representing the phosphofructokinase gene be?

What extends from the methylguanosine cap at the start of an mRNA to the AUG initiation codon?

There are genes on the X chromosome that manage to escape inactivation by an as yet unknown mechanism.What particular genes are included in this group and what might be the reason that they remain activated?

The enzymes that remove acetyl groups from histones in the chromatin are ________.

What phenomenon greatly expands the diversity of regulatory factors that can be generated from a limited number of polypeptides?