Question 1

In what direction is mRNA produced?

Accepted Answer

A) 3' to 5' direction 
B) 5' to 3' direction 
C) N-terminal to C-terminal direction 
D) C-terminal to N-terminal direction 
E) N-terminal to 3' direction 
A) 3' to 5' direction 
B) 5' to 3' direction 
C) N-terminal to C-terminal direction 
D) C-terminal to N-terminal direction 
E) N-terminal to 3' direction

Question 2

Why has the One Gene - One Polypeptide hypothesis had to be modified?

Accepted Answer

A) It was totally wrong. 
B) Genes can be spliced differently to generate a variety of related polypeptides. 
C) Enzymes sometimes consist of more than one polypeptide,each of which is coded for by its own gene. 
D) Enzymes actually code for genes. 
E) Polypeptides code for genes. 
A) It was totally wrong. 
B) Genes can be spliced differently to generate a variety of related polypeptides. 
C) Enzymes sometimes consist of more than one polypeptide,each of which is coded for by its own gene. 
D) Enzymes actually code for genes. 
E) Polypeptides code for genes.

Question 3

The initiator tRNA enters the 30S ribosomal subunit at the ____ during prokaryotic protein synthesis.

Accepted Answer

A) A site 
B) P site 
C) E site 
D) Q site 
E) 50S attachment point 
A) A site 
B) P site 
C) E site 
D) Q site 
E) 50S attachment point

Question 4

RNA interference can be used to _____ the production of a particular enzyme so that the effect of the enzyme _______ on the organism's _________ can be determined.

Accepted Answer

A) stop,deficiency,phenotype 
B) enhance,deficiency,phenotype 
C) stop,deficiency,genotype 
D) enhance,overexpression,phenotype 
E) stop,overexpression,genotype 
A) stop,deficiency,phenotype 
B) enhance,deficiency,phenotype 
C) stop,deficiency,genotype 
D) enhance,overexpression,phenotype 
E) stop,overexpression,genotype

Question 5

What is always the first amino acid incorporated at the N-terminus of a nascent polypeptide chain?

Accepted Answer

A) cysteine 
B) cystine 
C) methionine 
D) asparagine 
E) glycine 
A) cysteine 
B) cystine 
C) methionine 
D) asparagine 
E) glycine

Question 6

Most of the cellular RNA is in what form?

Accepted Answer

A) hnRNAs 
B) snoRNAs 
C) mRNAs 
D) rRNAs 
E) hmRNAs 
A) hnRNAs 
B) snoRNAs 
C) mRNAs 
D) rRNAs 
E) hmRNAs

Question 7

What did Beadle and Tatum use to generate mutations in their experimental organism?

Accepted Answer

A) mustard gas 
B) irradiation with ultraviolet light 
C) fluorescent dyes 
D) ethidium bromide 
E) Coomassie blue 
A) mustard gas 
B) irradiation with ultraviolet light 
C) fluorescent dyes 
D) ethidium bromide 
E) Coomassie blue

Question 8

What is the supposed function of the loops in tRNAs?

Accepted Answer

A) They bind to amino acids. 
B) They bind to other tRNAs. 
C) They bind to mRNAs. 
D) They serve as potential recognition sites for various proteins. 
E) They increase the buoyant density of tRNAs. 
A) They bind to amino acids. 
B) They bind to other tRNAs. 
C) They bind to mRNAs. 
D) They serve as potential recognition sites for various proteins. 
E) They increase the buoyant density of tRNAs.

Question 9

What chemical group is attached to the first methionine in a polypeptide chain in prokaryotes?

Accepted Answer

A) a formyl group 
B) a methyl group 
C) an acetyl group 
D) a phosphate group 
E) a glutamyl group 
A) a formyl group 
B) a methyl group 
C) an acetyl group 
D) a phosphate group 
E) a glutamyl group

Question 10

You incubate eukaryotic cells for 30 minutes in 3H-uridine and then immediately kill the cells and extract the RNA.Where does the radiolabel appear after this experiment?

Accepted Answer

A) in larger RNAs in the cytoplasm 
B) in smaller RNAs in the mitochondria 
C) in smaller RNAs in the cytoplasm 
D) in larger RNAs in the mitochondria 
E) in moderately sized RNAs in the Golgi complex 
A) in larger RNAs in the cytoplasm 
B) in smaller RNAs in the mitochondria 
C) in smaller RNAs in the cytoplasm 
D) in larger RNAs in the mitochondria 
E) in moderately sized RNAs in the Golgi complex

Question 11

Alcaptonuria is a genetic disease that is characterized by _________.

Accepted Answer

A) urine turning dark upon exposure to the air 
B) mental retardation 
C) paralysis 
D) urine smelling and tasting like maple syrup 
E) high fevers 
A) urine turning dark upon exposure to the air 
B) mental retardation 
C) paralysis 
D) urine smelling and tasting like maple syrup 
E) high fevers

Question 12

The chromosome regions containing rDNA are located in.

Accepted Answer

A) terminators 
B) nucleoli 
C) nucleosomes 
D) ribostores 
E) telomeres 
A) terminators 
B) nucleoli 
C) nucleosomes 
D) ribostores 
E) telomeres

Question 13

The genetic code has 64 codons,while there are only 20 amino acids.Thus,some amino acids are coded for by more than one codon.As a result,the genetic code is said to be ________.

Accepted Answer

A) regenerate 
B) degenerate 
C) overlapping 
D) nonoverlapping 
E) nonspecific 
A) regenerate 
B) degenerate 
C) overlapping 
D) nonoverlapping 
E) nonspecific

Question 14

RNA polymerase II promoters are located on the ____ side of each transcription unit.

Accepted Answer

A) 3' 
B) 5' 
C) N-terminal 
D) C-terminal 
E) internal 
A) 3' 
B) 5' 
C) N-terminal 
D) C-terminal 
E) internal

Question 15

Which codon below usually serves as the initiation codon?

Accepted Answer

A) 5'-AUG-3' 
B) 5'-GUG-3' 
C) 3'-AUG-5' 
D) 3'-GUG-3' 
E) 3'-UAC-5' 
A) 5'-AUG-3' 
B) 5'-GUG-3' 
C) 3'-AUG-5' 
D) 3'-GUG-3' 
E) 3'-UAC-5'

Question 16

The nucleotide at which transcription is initiated is called _____.

Accepted Answer

A) 0 
B) +1 
C) -1 
D) +2 
E) -2 
A) 0 
B) +1 
C) -1 
D) +2 
E) -2

Question 17

What did Archibald Garrod call diseases like alcaptonuria?

Accepted Answer

A) deadly diseases 
B) inborn errors of transcription 
C) homogentisms 
D) errors 
E) inborn errors of metabolism 
A) deadly diseases 
B) inborn errors of transcription 
C) homogentisms 
D) errors 
E) inborn errors of metabolism

Question 18

What molecule is TFIIH known to phosphorylate?

Accepted Answer

A) a G protein 
B) RNA polymerase II 
C) RNA polymerase IV 
D) peptidyltransferase 
E) DNA helicase 
A) a G protein 
B) RNA polymerase II 
C) RNA polymerase IV 
D) peptidyltransferase 
E) DNA helicase

Question 19

The process of RNA synthesis and splicing can occasionally give rise to mutations that introduce a termination codon in the middle of a coding sequence.How do cells detect and deal with these mutations?

Accepted Answer

mRNAs containing such mutations are tran

Question 20

The mechanical changes that ribosomes undergo are driven by energy from ______.

Accepted Answer

A) GTP hydrolysis 
B) ATP hydrolysis 
C) ADP hydrolysis 
D) an electrochemical gradient 
E) a concentration gradient 
A) GTP hydrolysis 
B) ATP hydrolysis 
C) ADP hydrolysis 
D) an electrochemical gradient 
E) a concentration gradient

In what direction is mRNA produced?

Why has the One Gene - One Polypeptide hypothesis had to be modified?

The initiator tRNA enters the 30S ribosomal subunit at the ____ during prokaryotic protein synthesis.

RNA interference can be used to _ the production of a particular enzyme so that the effect of the enzyme _ on the organism's _______ can be determined.

What is always the first amino acid incorporated at the N-terminus of a nascent polypeptide chain?

Most of the cellular RNA is in what form?

What did Beadle and Tatum use to generate mutations in their experimental organism?

What is the supposed function of the loops in tRNAs?

What chemical group is attached to the first methionine in a polypeptide chain in prokaryotes?

You incubate eukaryotic cells for 30 minutes in 3H-uridine and then immediately kill the cells and extract the RNA.Where does the radiolabel appear after this experiment?

Alcaptonuria is a genetic disease that is characterized by _________.

The chromosome regions containing rDNA are located in.

The genetic code has 64 codons,while there are only 20 amino acids.Thus,some amino acids are coded for by more than one codon.As a result,the genetic code is said to be ________.

RNA polymerase II promoters are located on the ____ side of each transcription unit.

Which codon below usually serves as the initiation codon?

The nucleotide at which transcription is initiated is called _____.

What did Archibald Garrod call diseases like alcaptonuria?

What molecule is TFIIH known to phosphorylate?

The process of RNA synthesis and splicing can occasionally give rise to mutations that introduce a termination codon in the middle of a coding sequence.How do cells detect and deal with these mutations?

The mechanical changes that ribosomes undergo are driven by energy from ______.

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

Exam 11: Gene Expression: From Transcription to Translation

In what direction is mRNA produced?

Why has the One Gene - One Polypeptide hypothesis had to be modified?

The initiator tRNA enters the 30S ribosomal subunit at the ____ during prokaryotic protein synthesis.

RNA interference can be used to _____ the production of a particular enzyme so that the effect of the enzyme _______ on the organism's _________ can be determined.

What is always the first amino acid incorporated at the N-terminus of a nascent polypeptide chain?

Most of the cellular RNA is in what form?

What did Beadle and Tatum use to generate mutations in their experimental organism?

What is the supposed function of the loops in tRNAs?

What chemical group is attached to the first methionine in a polypeptide chain in prokaryotes?

You incubate eukaryotic cells for 30 minutes in 3H-uridine and then immediately kill the cells and extract the RNA.Where does the radiolabel appear after this experiment?

Alcaptonuria is a genetic disease that is characterized by _________.

The chromosome regions containing rDNA are located in.

The genetic code has 64 codons,while there are only 20 amino acids.Thus,some amino acids are coded for by more than one codon.As a result,the genetic code is said to be ________.

RNA polymerase II promoters are located on the ____ side of each transcription unit.

Which codon below usually serves as the initiation codon?

The nucleotide at which transcription is initiated is called _____.

What did Archibald Garrod call diseases like alcaptonuria?

What molecule is TFIIH known to phosphorylate?

The process of RNA synthesis and splicing can occasionally give rise to mutations that introduce a termination codon in the middle of a coding sequence.How do cells detect and deal with these mutations?

The mechanical changes that ribosomes undergo are driven by energy from ______.

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

RNA interference can be used to _ the production of a particular enzyme so that the effect of the enzyme _ on the organism's _______ can be determined.