Exam 11: Gene Expression: From Transcription to Translation

Before the genetic code was actually known,Francis Crick predicted that it was degenerate.What piece of evidence led him to make this prediction?

Where are the unusual bases of tRNAs predominantly concentrated?

The snoRNA genes are found in the ______ of genes coding for polypeptides involved in _______.

What enzyme is responsible for covalently linking amino acids to the 3'-end of the cognate tRNA?

The corresponding segment of DNA from which the primary transcript is transcribed is called a _____.

In an experiment,you purify a cysteine-charged tRNA and chemically alter the amino acid attached to it converting it to alanine.You place this charged tRNA in a cell-free protein-synthesizing system with all of the other charged tRNAs,mRNA and other substances needed for the synthesis of proteins.What,if anything,will be different from the normal protein coded for by the mRNA in the mixture?

With what protein does the double-stranded miRNA become associated? The RNA duplex then is disassembled and one of the single strands is incorporated into a RISC complex.

A pri-mRNA is cleaved within the nucleus by an enzyme called _______ into a shorter,double-stranded,hairpin-shaped precursor called a ________.

How would you describe the arrangement of the 5S rRNA genes?