Exam 33: Specific Adaptive Immunity

Autoimmunity and autoimmune disease are both most often fatal.

Class I major histocompatibility complex molecules are found on ____________ cells.

T-cell receptors can only recognize antigens on the surfaces of antigen-presenting cells; they cannot bind free antigen.

An immune complex resulting from an interaction of antibody with cells or particles which becomes large enough to settle out of solution is called a(n)

If the clonal selection theory is correct, there exists at least one lymphocyte capable of synthesizing an antibody specific to each antigen prior to exposure to the antigen.

Which of the following types of immunoglobulins is most abundant in serum?

The __________ chains are structurally distinct for each immunoglobulin class.

Which type(s) of antigen-presenting cell can activate T cells?

During activation of a T cell, the cytokine it produces to stimulate its own proliferation is

The protein chains in a complete antibody molecule are connected to each other by ___________ bonds.

Tumor cells of the immune system that produce large quantities of antibodies and can be readily cultivated are called

If a T cell that has received signal 1 for activation fails to also receive signal 2 it may become

Botulinum antitoxin produced in a horse and given to a human suffering from botulism food poisoning is an example of

Superantigens exert their damaging effects by

Pentameric IgM activates complement up to 20-fold more effectively than does the hexameric form of IgM.

A type of antibody light chain is the ___________ chain.

Which of the following is not true concerning T-independent B cell activation?

T cells attack

Which of the following is a characteristic associated with secondary antibody responses?

Each antigen has one antigenic determinant site or epitope.