Exam 10: Preventing Infection at Mucosal Surfaces

In addition to M cells,_____ can capture pathogens directly from the lumen of the gut.

_____ compensates for the absence of secretory IgA in selective IgA deficiency because it can be secreted by mucosal tissues using the same receptor needed for transcytosis.

M cells,unlike dendritic cells,_____.

The significance of MAdCAM-1 on the endothelium of blood vessels is that it binds to _____.

Explain why individuals who have the condition selective IgA deficiency do not succumb to repeated infection through mucosal surfaces.

All of the following are expressed by intestinal epithelial cells except _____.

In which of the following tissues is IgA2 produced at approximately twice the level of IgA1?

Describe the route that a Peyer's patch-activated T lymphocyte follows,beginning with a naive T lymphocyte in a high endothelial venule and ending with an effector T lymphocyte in the lamina propria.

Why do children who have had their tonsils or adenoids removed respond less effectively to the oral polio vaccine than children who still have these tissues?

Secretory IgA and _____ can bind to the poly-Ig receptor and be transported into the lumen of the gut or across other mucosal surfaces.

Waldeyer's ring includes which of the following? (Select all that apply.)

Which of the following migrates from non-mucosal tissue to draining lymph nodes to facilitate the induction of adaptive immune responses?

_____ is the vascular addressin found on endothelial cells of intestinal mucosa that binds to integrins of gut-homing effector lymphocytes.

If a B cell has been activated by antigen in the mucosa of the respiratory tract,then _____.(Select all that apply.)

What is the function of the TNF-family cytokine APRIL made by epithelial cells of the colon?

Secretory IgA is best described as _____.

Mucosae of a healthy intestinal tract _____.(Select all that apply.)

Describe two ways in which dendritic cells capture antigen from the intestine for presentation to T lymphocytes.