Question 1

_____ is a soluble protein.(Select all that apply.)

Accepted Answer

A) TLR4 
B) CD14 
C) lipopolysaccharide-binding protein (LBP) 
D) CXCR1 
E) mannose-binding lectin. 
A) TLR4 
B) CD14 
C) lipopolysaccharide-binding protein (LBP) 
D) CXCR1 
E) mannose-binding lectin. C,E

Question 2

of the following characterize serum amyloid protein except _____.

Accepted Answer

A) it contains approximately 100 amino acids 
B) it interacts with CD36 scavenger receptor 
C) it increases in concentration by 25% or more in response to infection 
D) it associates with high-density lipoprotein particles 
E) it activates the classical pathway of complement activation. 
A) it contains approximately 100 amino acids 
B) it interacts with CD36 scavenger receptor 
C) it increases in concentration by 25% or more in response to infection 
D) it associates with high-density lipoprotein particles 
E) it activates the classical pathway of complement activation. E

Question 3

Toll-like receptors are located _____.

Accepted Answer

A) only on the plasma membrane 
B) on the plasma membrane and the mitochondrial outer membrane 
C) on the plasma membrane and endosomal membranes 
D) only in the cytoplasm 
E) inside inflammasomes. 
A) only on the plasma membrane 
B) on the plasma membrane and the mitochondrial outer membrane 
C) on the plasma membrane and endosomal membranes 
D) only in the cytoplasm 
E) inside inflammasomes. C

Question 4

The name given to cytokines that recruit cells to move towards areas of inflammation is _____.

Accepted Answer

A) chemokines 
B) caspase-recruitment domains (CARDs) 
C) inflammakines 
D) adhesion molecules 
E) pyrogens. 
A) chemokines 
B) caspase-recruitment domains (CARDs) 
C) inflammakines 
D) adhesion molecules 
E) pyrogens.

Question 5

Match between columns
                        Premises: chronic granulomatous disease
X-linked hypohidrotic ectodermal dysplasia and immunodeficiency (NEMO deficiency)
septic shock

Accepted Answer

The Answer of failure to translocate NF\kappaB and activate macrophages is...

Question 6

An adaptor protein in the inflammasome is required to link _____ to the NOD-like receptor NLRP3.

Accepted Answer

A) MyD88 
B) procaspase-1 
C) RIPK2 
D) TAKI 
E) IKK. 
A) MyD88 
B) procaspase-1 
C) RIPK2 
D) TAKI 
E) IKK.

Question 7

All of the following acute-phase proteins increase in concentration in the plasma during inflammation with the exception of _____.

Accepted Answer

A) albumin 
B) serum amyloid A protein 
C) fibrinogen 
D) C3 
E) mannose-binding lectin. 
A) albumin 
B) serum amyloid A protein 
C) fibrinogen 
D) C3 
E) mannose-binding lectin.

Question 8

Lectins recognize microbial _____.

Accepted Answer

A) phosphate-containing lipoteichoic acids 
B) nucleic acids 
C) carbohydrates 
D) flagellin 
E) sulfated polysaccharides. 
A) phosphate-containing lipoteichoic acids 
B) nucleic acids 
C) carbohydrates 
D) flagellin 
E) sulfated polysaccharides.

Question 9

Describe the two different domains of TLRs and their respective functions.

Accepted Answer

The first domain of the TLR is an extrac

Question 10

_____ is/are needed to minimize the damaging effects to neighboring host cells during a respiratory burst.

Accepted Answer

A) Catalase activity 
B) Complement control proteins 
C) NADPH oxidase activity 
D) Neutrophil mobilization 
E) Superoxide dismutase activity. 
A) Catalase activity 
B) Complement control proteins 
C) NADPH oxidase activity 
D) Neutrophil mobilization 
E) Superoxide dismutase activity.

Question 11

Chemokine receptors form complexes with _____ after binding to their ligands.

Accepted Answer

A) inflammasome components 
B) pro-IL-1\beta 
C) potassium channels 
D) GTP-binding proteins 
E) tertiary granules. 
A) inflammasome components 
B) pro-IL-1\beta 
C) potassium channels 
D) GTP-binding proteins 
E) tertiary granules.

Question 12

The following cytokines activate NK cells early in the course of a viral infection with the exception of _____.

Accepted Answer

A) IFN-\alpha 
B) IFN-\beta 
C) IFN-\gamma 
D) IL-12 
E) IL-15. 
A) IFN-\alpha 
B) IFN-\beta 
C) IFN-\gamma 
D) IL-12 
E) IL-15.

Question 13

The lectin pathway of complement activation is induced by _____.

Accepted Answer

A) C-reactive protein 
B) antibodies bound to pathogens 
C) mannose-binding lectin 
D) iC3Bb 
E) terminal components of the complement pathway. 
A) C-reactive protein 
B) antibodies bound to pathogens 
C) mannose-binding lectin 
D) iC3Bb 
E) terminal components of the complement pathway.

Question 14

Match between columns
                        Premises: TLR3
TLR4:TLR4
CR3
lectin receptor
CR4
scavenger receptor
TLR5
CR1

Accepted Answer

The Answer of filamentous hemagglutinin and C3b and negatively charged is...

Question 15

After recognizing its ligand,a NOD receptor interacts with a signaling protein called _____,which is a serine-threonine kinase that phosphorylates TAKI.

Accepted Answer

A) CARD 
B) NLRP3 
C) RIPK2 
D) MARCO 
E) SR-A. 
A) CARD 
B) NLRP3 
C) RIPK2 
D) MARCO 
E) SR-A.

Question 16

Explain why TLRs can detect many different species of microbes despite the limited number of different TLR proteins.

Accepted Answer

Because many pathogens possess features

Question 17

Describe the different functions performed by the two subpopulations of NK cells in the blood and how they are distinguished. B.How does this compare with NK-cell subpopulations in other tissues?

Accepted Answer

The answer of Describe the different functions performed by the...

Question 18

Which of the following is not a characteristic of mannose-binding lectin?

Accepted Answer

A) acts as an opsonin by binding to mannose-containing carbohydrates of pathogens 
B) synthesized by hepatocytes 
C) induced by elevated IL-6 levels 
D) a member of the pentraxin family 
E) triggers the alternative pathway of complement activation. 
A) acts as an opsonin by binding to mannose-containing carbohydrates of pathogens 
B) synthesized by hepatocytes 
C) induced by elevated IL-6 levels 
D) a member of the pentraxin family 
E) triggers the alternative pathway of complement activation.

Question 19

Which of the following pairs is mismatched?

Accepted Answer

A) primary granules: azurophilic granules 
B) secondary granules: unsaturated lactoferrin 
C) azurophilic granules: myeloperoxidase 
D) gelatinase: iron sequestration 
E) tertiary granules: natural killer cells. 
A) primary granules: azurophilic granules 
B) secondary granules: unsaturated lactoferrin 
C) azurophilic granules: myeloperoxidase 
D) gelatinase: iron sequestration 
E) tertiary granules: natural killer cells.

Question 20

Which of the following properties is common to macrophages and neutrophils in an uninfected individual?

Accepted Answer

A) life-span 
B) anatomical location 
C) ability to phagocytose 
D) morphology 
E) formation of pus. 
A) life-span 
B) anatomical location 
C) ability to phagocytose 
D) morphology 
E) formation of pus.

_____ is a soluble protein.(Select all that apply.)

of the following characterize serum amyloid protein except _____.

Toll-like receptors are located _____.

The name given to cytokines that recruit cells to move towards areas of inflammation is _____.

An adaptor protein in the inflammasome is required to link _____ to the NOD-like receptor NLRP3.

All of the following acute-phase proteins increase in concentration in the plasma during inflammation with the exception of _____.

Lectins recognize microbial _____.

Describe the two different domains of TLRs and their respective functions.

_____ is/are needed to minimize the damaging effects to neighboring host cells during a respiratory burst.

Chemokine receptors form complexes with _____ after binding to their ligands.

The following cytokines activate NK cells early in the course of a viral infection with the exception of _____.

The lectin pathway of complement activation is induced by _____.

After recognizing its ligand,a NOD receptor interacts with a signaling protein called _____,which is a serine-threonine kinase that phosphorylates TAKI.

Explain why TLRs can detect many different species of microbes despite the limited number of different TLR proteins.

Describe the different functions performed by the two subpopulations of NK cells in the blood and how they are distinguished. B.How does this compare with NK-cell subpopulations in other tissues?

Which of the following is not a characteristic of mannose-binding lectin?

Which of the following pairs is mismatched?

Which of the following properties is common to macrophages and neutrophils in an uninfected individual?

Elements of the Immune System and Their Roles in Defense

Innate Immunity: the Immediate Response to Infection

Antibody Structure and the Generation of B-Cell Diversity

Antigen Recognition by T Lymphocytes

The Development of B Lymphocytes

The Development of T Lymphocytes

T Cell-Mediated Immunity

Immunity Mediated by B Cells and Antibodies

Preventing Infection at Mucosal Surfaces

Immunological Memory and Vaccination

Coevolution of Innate and Adaptive Immunity

Failures of the Bodys Defenses

Ige-Mediated Immunity and Allergy

Transplantation of Tissues and Organs

Disruption of Healthy Tissue by the Adaptive Immune Response

Cancer and Its Interactions With the Immune System

Filters

Exam 3: Innate Immunity: the Induced Response to Infection

_____ is a soluble protein.(Select all that apply.)

of the following characterize serum amyloid protein except _____.

Toll-like receptors are located _____.

The name given to cytokines that recruit cells to move towards areas of inflammation is _____.

An adaptor protein in the inflammasome is required to link _____ to the NOD-like receptor NLRP3.

All of the following acute-phase proteins increase in concentration in the plasma during inflammation with the exception of _____.

Lectins recognize microbial _____.

Describe the two different domains of TLRs and their respective functions.

_____ is/are needed to minimize the damaging effects to neighboring host cells during a respiratory burst.

Chemokine receptors form complexes with _____ after binding to their ligands.

The following cytokines activate NK cells early in the course of a viral infection with the exception of _____.

The lectin pathway of complement activation is induced by _____.

After recognizing its ligand,a NOD receptor interacts with a signaling protein called _____,which is a serine-threonine kinase that phosphorylates TAKI.

Explain why TLRs can detect many different species of microbes despite the limited number of different TLR proteins.

Describe the different functions performed by the two subpopulations of NK cells in the blood and how they are distinguished. B.How does this compare with NK-cell subpopulations in other tissues?

Which of the following is not a characteristic of mannose-binding lectin?

Which of the following pairs is mismatched?

Which of the following properties is common to macrophages and neutrophils in an uninfected individual?

Elements of the Immune System and Their Roles in Defense

Innate Immunity: the Immediate Response to Infection

Antibody Structure and the Generation of B-Cell Diversity

Antigen Recognition by T Lymphocytes

The Development of B Lymphocytes

The Development of T Lymphocytes

T Cell-Mediated Immunity

Immunity Mediated by B Cells and Antibodies

Preventing Infection at Mucosal Surfaces

Immunological Memory and Vaccination

Coevolution of Innate and Adaptive Immunity

Failures of the Bodys Defenses

Ige-Mediated Immunity and Allergy

Transplantation of Tissues and Organs

Disruption of Healthy Tissue by the Adaptive Immune Response

Cancer and Its Interactions With the Immune System

Filters