Question 1

A benign tumor of glandular tissue is known as a(n)_____.

Accepted Answer

A) sarcoma 
B) myeloma 
C) adenoma 
D) adenocarcinoma 
E) lymphoma. 
A) sarcoma 
B) myeloma 
C) adenoma 
D) adenocarcinoma 
E) lymphoma. C

Question 2

Provide examples where tumor cells transferred between a donor and a recipient are either (A)rejected and do not cause cancer,or (B)not rejected and cause cancer.

Accepted Answer

A.	If primary tumor cells are donated between MHC-disparate mice, the cytotoxic T cells of the recipient recognize differences in MHC class I and kill the tumor cells.
	B.	(i) The marsupial known as the Tasmanian devil can pass tumor cells between individuals when fighting and biting each other’s faces. Because of limited MHC diversity in the species, there is a lack of allograft rejection, and the tumor cells establish themselves at the site of facial injury. (ii) In humans, residual tumor cells in an HLA-matched transplanted organ will not be rejected because the recipient is immunosuppressed and unable to mount an antitumor immune response.

Question 3

Proteins not expressed on normal cells but found on tumor cells are called _____.

Accepted Answer

A) cancer stem cell antigens 
B) oncogenic antigens 
C) tumor-associated antigens 
D) tumor-specific antigens 
E) proto-oncogene products. 
A) cancer stem cell antigens 
B) oncogenic antigens 
C) tumor-associated antigens 
D) tumor-specific antigens 
E) proto-oncogene products. D

Question 4

Systemic distribution of cancer cells to other sites of the body through the bloodstream or lymph is a process known as _____.

Accepted Answer

A) apoptosis 
B) neoplasia 
C) angiogenesis 
D) metastasis 
E) malignant transformation. 
A) apoptosis 
B) neoplasia 
C) angiogenesis 
D) metastasis 
E) malignant transformation.

Question 5

Explain why the incidence of cancer is higher in the elderly than in young people.

Accepted Answer

For a cell to become cancerous and under

Question 6

Human herpesvirus 8 (HHV8)is associated with the development of _____ in immunocompromised patients.

Accepted Answer

A) Burkitt's lymphoma 
B) chronic myeloid leukemia 
C) melanoma 
D) myeloma 
E) Kaposi's sarcoma. 
A) Burkitt's lymphoma 
B) chronic myeloid leukemia 
C) melanoma 
D) myeloma 
E) Kaposi's sarcoma.

Question 7

Which of the following cell types in a tumor biopsy would not be associated with a promising prognosis?

Accepted Answer

A) B cells 
B) memory T cells 
C) TFH cells 
D) regulatory T cells 
E) cytotoxic T cells. 
A) B cells 
B) memory T cells 
C) TFH cells 
D) regulatory T cells 
E) cytotoxic T cells.

Question 8

A malignant tumor is characterized by which of the following features? (Select all that apply.)

Accepted Answer

A) encapsulation 
B) localized 
C) restricted in size 
D) metastasizes to distant sites 
E) results from multiple mutations affecting cell division or survival. 
A) encapsulation 
B) localized 
C) restricted in size 
D) metastasizes to distant sites 
E) results from multiple mutations affecting cell division or survival.

Question 9

_____ agents usually cause single nucleotide substitutions in DNA,whereas _____ agents produce more significant damage to DNA.

Accepted Answer

A) mutagenic; carcinogenic 
B) chemical; physical 
C) benign; malignant 
D) tumor-associated; tumor-specific 
E) benign; oncogenic. 
A) mutagenic; carcinogenic 
B) chemical; physical 
C) benign; malignant 
D) tumor-associated; tumor-specific 
E) benign; oncogenic.

Question 10

_____ describes the condition in which a cell becomes able to cause cancer.

Accepted Answer

A) Malignant mutation 
B) Malignant recombination 
C) Malignant neoplasm 
D) Malignant transformation 
E) Malignant suppression. 
A) Malignant mutation 
B) Malignant recombination 
C) Malignant neoplasm 
D) Malignant transformation 
E) Malignant suppression.

Question 11

A.How is it possible for a tumor-specific antigen to be composed of a unique sequence of amino acids not encoded in the genome of the tumor cell?
B.Give a specific example.

Accepted Answer

A.The proteasome not only degrades prote

Question 12

Adoptive transfer of sipuleucel-T-primed dendritic cells is a form of immunotherapy currently used for the treatment of _____.

Accepted Answer

A) late-stage metastatic prostate cancer 
B) multiple myeloma 
C) chronic myelogenous leukemia 
D) melanoma 
E) cervical cancer. 
A) late-stage metastatic prostate cancer 
B) multiple myeloma 
C) chronic myelogenous leukemia 
D) melanoma 
E) cervical cancer.

Question 13

Human papillomaviruses express proteins that bind to _____ and block its function.(Select all that apply.)

Accepted Answer

A) MIC glycoproteins 
B) p53 
C) CT antigens 
D) TLR4 
E) Rb. 
A) MIC glycoproteins 
B) p53 
C) CT antigens 
D) TLR4 
E) Rb.

Question 14

A tumor-associated antigen normally expressed only in the testis is called a _____ antigen.

Accepted Answer

A) MIC 
B) CT 
C) male-specific 
D) sex chromosome-encoded 
E) privileged. 
A) MIC 
B) CT 
C) male-specific 
D) sex chromosome-encoded 
E) privileged.

Question 15

Match between columns
                        Premises: ipilimumab
brentuximab
ibritumomab
lirilumab
nivolumab
elotuzumab
vemurafenib

Accepted Answer

The Answer of CD30 and CD20 and BRAF and programmed is...

Question 16

An example of a physical agent that increases an individual's predisposition to developing cancer is_____.(Select all that apply.)

Accepted Answer

A) cigarette smoke 
B) X-rays 
C) ultraviolet radiation 
D) asbestos 
E) exposure to radioactive sources. 
A) cigarette smoke 
B) X-rays 
C) ultraviolet radiation 
D) asbestos 
E) exposure to radioactive sources.

Question 17

A.What is Li-Fraumeni syndrome?
B.What is the underlying cause?

Accepted Answer

A.Li-Fraumeni syndrome is a condition in

Question 18

Provide an example of a monoclonal antibody that can be modified differently to either detect or eradicate a tumor.

Accepted Answer

Ibritumomab,an anti-CD20 antibody,is use

Question 19

A protein expressed in response to damage to DNA that results in death to the cell is _____.

Accepted Answer

A) Ras 
B) p53 
C) Rb 
D) Abl 
E) MAGEA1. 
A) Ras 
B) p53 
C) Rb 
D) Abl 
E) MAGEA1.

Question 20

Li-Fraumeni syndrome is linked to a greater risk of cancer as a result of the inheritance of a germline mutation in one copy of _____.

Accepted Answer

A) TLR-9 
B) p53 
C) CTLA4 
D) heat-shock protein 
E) Rb. 
A) TLR-9 
B) p53 
C) CTLA4 
D) heat-shock protein 
E) Rb.

A benign tumor of glandular tissue is known as a(n)_____.

Provide examples where tumor cells transferred between a donor and a recipient are either (A)rejected and do not cause cancer,or (B)not rejected and cause cancer.

Proteins not expressed on normal cells but found on tumor cells are called _____.

Systemic distribution of cancer cells to other sites of the body through the bloodstream or lymph is a process known as _____.

Explain why the incidence of cancer is higher in the elderly than in young people.

Human herpesvirus 8 (HHV8)is associated with the development of _____ in immunocompromised patients.

Which of the following cell types in a tumor biopsy would not be associated with a promising prognosis?

A malignant tumor is characterized by which of the following features? (Select all that apply.)

_ agents usually cause single nucleotide substitutions in DNA,whereas _ agents produce more significant damage to DNA.

_____ describes the condition in which a cell becomes able to cause cancer.

A.How is it possible for a tumor-specific antigen to be composed of a unique sequence of amino acids not encoded in the genome of the tumor cell? B.Give a specific example.

Adoptive transfer of sipuleucel-T-primed dendritic cells is a form of immunotherapy currently used for the treatment of _____.

Human papillomaviruses express proteins that bind to _____ and block its function.(Select all that apply.)

A tumor-associated antigen normally expressed only in the testis is called a _____ antigen.

An example of a physical agent that increases an individual's predisposition to developing cancer is_____.(Select all that apply.)

A.What is Li-Fraumeni syndrome? B.What is the underlying cause?

Provide an example of a monoclonal antibody that can be modified differently to either detect or eradicate a tumor.

A protein expressed in response to damage to DNA that results in death to the cell is _____.

Li-Fraumeni syndrome is linked to a greater risk of cancer as a result of the inheritance of a germline mutation in one copy of _____.

Elements of the Immune System and Their Roles in Defense

Innate Immunity: the Immediate Response to Infection

Innate Immunity: the Induced Response to Infection

Antibody Structure and the Generation of B-Cell Diversity

Antigen Recognition by T Lymphocytes

The Development of B Lymphocytes

The Development of T Lymphocytes

T Cell-Mediated Immunity

Immunity Mediated by B Cells and Antibodies

Preventing Infection at Mucosal Surfaces

Immunological Memory and Vaccination

Coevolution of Innate and Adaptive Immunity

Failures of the Bodys Defenses

Ige-Mediated Immunity and Allergy

Transplantation of Tissues and Organs

Disruption of Healthy Tissue by the Adaptive Immune Response

Filters

Exam 17: Cancer and Its Interactions With the Immune System

A benign tumor of glandular tissue is known as a(n)_____.

Provide examples where tumor cells transferred between a donor and a recipient are either (A)rejected and do not cause cancer,or (B)not rejected and cause cancer.

Proteins not expressed on normal cells but found on tumor cells are called _____.

Systemic distribution of cancer cells to other sites of the body through the bloodstream or lymph is a process known as _____.

Explain why the incidence of cancer is higher in the elderly than in young people.

Human herpesvirus 8 (HHV8)is associated with the development of _____ in immunocompromised patients.

Which of the following cell types in a tumor biopsy would not be associated with a promising prognosis?

A malignant tumor is characterized by which of the following features? (Select all that apply.)

_____ agents usually cause single nucleotide substitutions in DNA,whereas _____ agents produce more significant damage to DNA.

_____ describes the condition in which a cell becomes able to cause cancer.

A.How is it possible for a tumor-specific antigen to be composed of a unique sequence of amino acids not encoded in the genome of the tumor cell? B.Give a specific example.

Adoptive transfer of sipuleucel-T-primed dendritic cells is a form of immunotherapy currently used for the treatment of _____.

Human papillomaviruses express proteins that bind to _____ and block its function.(Select all that apply.)

A tumor-associated antigen normally expressed only in the testis is called a _____ antigen.

An example of a physical agent that increases an individual's predisposition to developing cancer is_____.(Select all that apply.)

A.What is Li-Fraumeni syndrome? B.What is the underlying cause?

Provide an example of a monoclonal antibody that can be modified differently to either detect or eradicate a tumor.

A protein expressed in response to damage to DNA that results in death to the cell is _____.

Li-Fraumeni syndrome is linked to a greater risk of cancer as a result of the inheritance of a germline mutation in one copy of _____.

Elements of the Immune System and Their Roles in Defense

Innate Immunity: the Immediate Response to Infection

Innate Immunity: the Induced Response to Infection

Antibody Structure and the Generation of B-Cell Diversity

Antigen Recognition by T Lymphocytes

The Development of B Lymphocytes

The Development of T Lymphocytes

T Cell-Mediated Immunity

Immunity Mediated by B Cells and Antibodies

Preventing Infection at Mucosal Surfaces

Immunological Memory and Vaccination

Coevolution of Innate and Adaptive Immunity

Failures of the Bodys Defenses

Ige-Mediated Immunity and Allergy

Transplantation of Tissues and Organs

Disruption of Healthy Tissue by the Adaptive Immune Response

Filters

_ agents usually cause single nucleotide substitutions in DNA,whereas _ agents produce more significant damage to DNA.