Exam 10: Preventing Infection at Mucosal Surfaces

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Describe four actions of effector CD4 TH2 cells that provide protection from infections by intestinal helminths and lead to expulsion of the parasites from the gastrointestinal tract.

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which anatomical location are Peyer's patches?

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The dominant immunoglobulin synthesized at mucosal surfaces is _____.

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All of the following are part of Waldeyer's ring except _____.

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Identify three locations where secretory IgA can bind to antigens in mucosal tissue,and for each give the fate of the antigen upon binding to secretory IgA.

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_____ assists in the differentiation of blood-derived monocytes into intestinal macrophages.

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Which of the following is not an activity associated with secretory IgA and secretory IgM in mucosal secretions?

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_____ microorganisms are microbes that colonize mucosal surfaces but under normal circumstances do not cause disease.

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IgA proteases produced by Streptococcus pneumoniae mediate all of the following effects except _____.

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Because the mucosae _____,this tissue is predisposed to infection.

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Explain how secondary lymphoid tissues of the mucosa are (A)similar to and (B)different from secondary lymphoid tissues elsewhere in the body (the systemic immune system).

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Unlike secreted mucins,membrane mucins _____.

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Intracytoplasmic bacteria in enterocytes of the gastrointestinal tract are detected by _____.

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Identify ways in which intestinal macrophages are (A)similar to and (B)different from macrophages in non-mucosal tissues.

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The cytokine influencing eosinophil development and function during helminth infections is _____.

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_____ makes up the membranes of connective tissue that help to anchor the gastrointestinal tract and hold it in place.

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Laboratory animals reared in gnotobiotic conditions _____.

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Secretory IgA binds to pathogens in all of the following locations except the _____.

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Match the term with its function.
FoxP3-positive T cells
antimicrobial products in crypts
M cells
suppress immune responses to food antigen
goblet cells
portals for antigen transport
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Responses:
FoxP3-positive T cells
antimicrobial products in crypts
M cells
suppress immune responses to food antigen
goblet cells
portals for antigen transport
brush border
microvilli on enterocytes for nutrient absorption
Paneth cells
mucus secretion
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The large population of microbes that contribute to the gut microbiota and have an important role in food processing are called _____.

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