Exam 2: Innate Immunity: the Immediate Response to Infection

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Which of the following complement components is an opsonin that binds to complement receptor 1 (CR1)on macrophages?

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Why is it important to expose the hydrophobic sites of C7 and C8 during the formation of the membrane-attack complex?

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The plasma proteins that counteract the activity of factor P by inactivating C3 convertase through the cleavage of C3b are _____.

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Which of the following are important in anchoring the membrane-attack complex to the membrane?

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Explain the steps that take place when a bacterium is opsonized via C3b:CR1 interaction between the bacterium and a resident macrophage in tissues.

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Identify the incorrectly paired molecular association.

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