Question 1

Which of these diseases would have a dramatic decrease in the CD3+ population?

Accepted Answer

A) adenosine deaminase deficiency 
B) common variable immunodeficiency 
C) Bruton's agammaglobulinemia 
D) transient hypogammaglobulinemia of infancy 
A) adenosine deaminase deficiency 
B) common variable immunodeficiency 
C) Bruton's agammaglobulinemia 
D) transient hypogammaglobulinemia of infancy A

Question 2

IgA deficiency is related to

Accepted Answer

A) early demise as the result of infection 
B) increased viral and fungal infections 
C) allergic reactions to plasma during surgery 
D) A and B 
A) early demise as the result of infection 
B) increased viral and fungal infections 
C) allergic reactions to plasma during surgery 
D) A and B C

Question 3

Selective IgA deficiencies occur mostly in

Accepted Answer

A) women 
B) men 
C) people from the Arabian Peninsula 
D) people from Asians 
A) women 
B) men 
C) people from the Arabian Peninsula 
D) people from Asians C

Question 4

Treatment of IgG hypogammaglobulinemia involves

Accepted Answer

A) a bone marrow transplant and infection management 
B) passive transfer of immune oglobulin and infection management 
C) plasmapheresis and infection management 
D) antibiotic use and chemotherapy 
A) a bone marrow transplant and infection management 
B) passive transfer of immune oglobulin and infection management 
C) plasmapheresis and infection management 
D) antibiotic use and chemotherapy

Question 5

Which of the following patients have no tonsils? Patients with

Accepted Answer

A) DiGeorge syndrome 
B) Common variable immunodeficiency 
C) Bruton's agammaglobulinemia 
D) Transient hypogammaglobulinemia of infancy 
A) DiGeorge syndrome 
B) Common variable immunodeficiency 
C) Bruton's agammaglobulinemia 
D) Transient hypogammaglobulinemia of infancy

Question 6

In DiGeorge syndrome,

Accepted Answer

A) some patients have complete lack of T cells 
B) all patients have a complete lack of T cells 
C) some patients have complete lack of B cells 
D) all patients have a complete lack of B cells 
A) some patients have complete lack of T cells 
B) all patients have a complete lack of T cells 
C) some patients have complete lack of B cells 
D) all patients have a complete lack of B cells

Question 7

(1)_________ infections suggest defects in antibody production, (2)________ infections suggest defects in T cell function, and both types of infections suggest(3) _________________

Accepted Answer

A) (1) fungal, (2) viral, (3) SCID 
B) (1) viral, (2) fungal, (3) neutrophil defects 
C) (1) bacterial, (2) viral, (3) SCID 
D) (1) bacterial (2) viral, (3) DiGeorge, 
A) (1) fungal, (2) viral, (3) SCID 
B) (1) viral, (2) fungal, (3) neutrophil defects 
C) (1) bacterial, (2) viral, (3) SCID 
D) (1) bacterial (2) viral, (3) DiGeorge,

Question 8

To measure T-cell function, we perfor0m

Accepted Answer

A) serum protein electrophoresis 
B) intradermal injection of tetanus toxoid 
C) the NBT test 
D) CD18 surface marker expression 
A) serum protein electrophoresis 
B) intradermal injection of tetanus toxoid 
C) the NBT test 
D) CD18 surface marker expression

Question 9

Purine nucleoside phosphorylase deficiency can cause

Accepted Answer

A) a buildup of excessive deoxy-GTP 
B) the buildup of deoxyadenosine and S-adenosylhomocysteine 
C) mutations in the IL-2 receptor 
D) a defect in glycosylation of immunoglobulin 
A) a buildup of excessive deoxy-GTP 
B) the buildup of deoxyadenosine and S-adenosylhomocysteine 
C) mutations in the IL-2 receptor 
D) a defect in glycosylation of immunoglobulin

Question 10

Several different defects can cause which of the following?

Accepted Answer

A) common variable immunodeficiency 
B) SCID 
C) selective IgA deficiency 
D) all of the above 
A) common variable immunodeficiency 
B) SCID 
C) selective IgA deficiency 
D) all of the above

Question 11

The nitroblue-tetrazolium test measures

Accepted Answer

A) B-cell function 
B) T-cell function 
C) complement function 
D) phagocytic cell function 
A) B-cell function 
B) T-cell function 
C) complement function 
D) phagocytic cell function

Question 12

Leukocyte adherence deficiency is due to a defect in

Accepted Answer

A) CD 18 
B) CD 19 
C) CD 20 
D) CD 21 
A) CD 18 
B) CD 19 
C) CD 20 
D) CD 21

Question 13

Bone marrow transplantation is the treatment of choice for

Accepted Answer

A) common variable immunodeficiency 
B) Bruton's agammaglobulinemia 
C) transient hypogammaglobulinemia of infancy 
D) X-SCID 
A) common variable immunodeficiency 
B) Bruton's agammaglobulinemia 
C) transient hypogammaglobulinemia of infancy 
D) X-SCID

Question 14

In this type of immunodeficiency, patients initially make their own immunoglobulin and then they develop

Accepted Answer

A) Bruton's hypogammaglobulinemia 
B) DiGeorge syndrome 
C) common variable hypogammaglobulinemia 
D) Stigel-Keil hypogammaglobulinemia 
A) Bruton's hypogammaglobulinemia 
B) DiGeorge syndrome 
C) common variable hypogammaglobulinemia 
D) Stigel-Keil hypogammaglobulinemia

Question 15

Acquired immunodeficiencies can be the result of

Accepted Answer

A) HIV 
B) alcoholism 
C) drug use 
D) all of the above 
E) A and C 
A) HIV 
B) alcoholism 
C) drug use 
D) all of the above 
E) A and C

Question 16

Infections that suggest defects in antibody production are

Accepted Answer

A) fungal 
B) viral 
C) bacterial 
D) all of these 
A) fungal 
B) viral 
C) bacterial 
D) all of these

Question 17

Treatment of DiGeorge syndrome can include

Accepted Answer

A) passive transfer of immunoglobulin 
B) bone marrow transplantation 
C) transplantation of a fetal thymus 
D) any of the above 
A) passive transfer of immunoglobulin 
B) bone marrow transplantation 
C) transplantation of a fetal thymus 
D) any of the above

Question 18

Lack of tonsils as an indicator of the lack of B cells is seen in baby boys with which of the following immunodeficiencies/

Accepted Answer

A) DiGeorge syndrome 
B) Bruton's disease 
C) Purine neucleoside phosphorylase 
D) LAD 
A) DiGeorge syndrome 
B) Bruton's disease 
C) Purine neucleoside phosphorylase 
D) LAD

Question 19

SCID is

Accepted Answer

A) always caused by Adenosine deaminase deficiency and results in no B or T cell response 
B) always caused by reticular dysgenesis and results in no B or T cell response 
C) a term used to describe a variety of different conditions that results in no B or T cell response 
D) caused by a missing piece (a small deletion) of chromosome 22 that results in no B or T cell response 
A) always caused by Adenosine deaminase deficiency and results in no B or T cell response 
B) always caused by reticular dysgenesis and results in no B or T cell response 
C) a term used to describe a variety of different conditions that results in no B or T cell response 
D) caused by a missing piece (a small deletion) of chromosome 22 that results in no B or T cell response

Question 20

In which of the following types of immunodeficiency do patients initially not make their own immunoglobulin and then they do

Accepted Answer

A) Bruton's hypogammaglobulinemia 
B) DiGeorge syndrome 
C) common variable hypogammaglobulinemia 
D) Stigel-Keil hypogammaglobulinemia 
E) transient hypogammaglobulinemia 
A) Bruton's hypogammaglobulinemia 
B) DiGeorge syndrome 
C) common variable hypogammaglobulinemia 
D) Stigel-Keil hypogammaglobulinemia 
E) transient hypogammaglobulinemia

Exam 15: Primary Immunodeficiency Diseases

Which of these diseases would have a dramatic decrease in the CD3+ population?

IgA deficiency is related to

Selective IgA deficiencies occur mostly in

Treatment of IgG hypogammaglobulinemia involves

Which of the following patients have no tonsils? Patients with

In DiGeorge syndrome,

(1)_________ infections suggest defects in antibody production, (2)________ infections suggest defects in T cell function, and both types of infections suggest(3) _________________

To measure T-cell function, we perfor0m

Purine nucleoside phosphorylase deficiency can cause

Several different defects can cause which of the following?

The nitroblue-tetrazolium test measures

Leukocyte adherence deficiency is due to a defect in

Bone marrow transplantation is the treatment of choice for

In this type of immunodeficiency, patients initially make their own immunoglobulin and then they develop

Acquired immunodeficiencies can be the result of

Infections that suggest defects in antibody production are

Treatment of DiGeorge syndrome can include

Lack of tonsils as an indicator of the lack of B cells is seen in baby boys with which of the following immunodeficiencies/

SCID is

In which of the following types of immunodeficiency do patients initially not make their own immunoglobulin and then they do

Introduction to Immunology

Antibody

Antigens-Epitopes and Immunogenicity

Cellular Immunity

Complement Pathways

Agglutination and Precipitation Reactions: the Unlabeled Immunoassays

Labeled Immunoassays

Serology Laboratory Math

Hypersensitivity Reactions

Autoimmunitysystemic

Autoimmunityorgan or Tissue Specific

Tumor Immunology

Hematopoeitc Malignancies

Immunology of Transplantation

Acquired Immunodeficiency Including Hiv and Aids

Hepatitis

Serology and Viruses Herpesviridae Family and Other Serologically

Bacterial Serology

Fungal Serology Parasitic Serology

Forensic Serology

Safety

Molecular Biology

Filters

(1)_ infections suggest defects in antibody production, (2) infections suggest defects in T cell function, and both types of infections suggest(3) _________