Exam 22: Exploring Synthetic Biology: Concepts, Techniques, and Applications

Which system is most likely to produce the stimulus-response curve shown here? In the systems shown below,the concentration of molecule 3 represents the stimulus,and the concentration of molecule 2 is the response.Molecule 1 is a substrate of molecule 3.Molecule 4 is an inactive form of molecule 3.Molecule 2 activates molecule 5.

What genus was chosen to host the first transplanted synthetic genome,and why?

What is a distinctive feature of the feed forward motif?

In a hypothetical situation in the future,you are a 22-year-old college student.Your doctor tells you that new technology has produced a lab test that can tell you your chances of developing a particular paralyzing disease by age 30.There is no treatment for this disease.Explain why you would or would not have this test done.

Why does the Hill function use maximum promoter activity as a parameter?

Which of the following is a synthetic molecule used in MAGE (Multiplex Automated Genome Engineering)?

In one application of synthetic biology in the human gut,a genetic circuit induces lysis of E.coli to release toxins when it encounters a particular pathogen.

Explain the four questions that guide research in systems biology.

In the Hill equation,what is the significance of the term "n"?

The araBAD operon contains an AND gate and a feed forward loop motif.

In a hypothetical situation in the future,you are a medical doctor,and you have just received the lab results for one of your patients,a 22-year-old college student.The test results show that this student has a 20% chance of developing a paralyzing disease by age 30.There is no known treatment for this disease.Your patient has now come in to find out the results of the test.What do you do?

Which of the following was not a component of the metabolic engineering strategy for artemisinic acid production?

Studies of complex biological networks would not be possible without high-throughput computational tools.

An emergent property is

Which of the following is the correct Hill function for activation?

Bistable circuits have only two possible states: ON or OFF.

In an analogy comparing computer systems to biological systems,which of the following pairs of components is most correct?

A molecular ratchet

Which of the following is not a parameter of the Hill function for activation?

A network motif is the same as a protein motif.