Question 1

Which of the following can cause allergy symptoms and inflammation by degranulation?

Accepted Answer

A)  dendritic cells 
B)  erythrocytes 
C)  macrophages 
D)  polymorphonuclear leukocytes 
A)  dendritic cells 
B)  erythrocytes 
C)  macrophages 
D)  polymorphonuclear leukocytes

Question 2

Mannose on mammalian cells is inaccessible to mannose-binding lectin.

Accepted Answer

A) True 
 B)False

Question 3

Antibodies are soluble proteins produced by T cells.

Accepted Answer

A) True 
 B)False

Question 4

The unique antigen-reactive proteins of T cells are

Accepted Answer

A)  antibodies. 
B)  immunoglobins. 
C)  T cell receptors. 
D)  None of these are correct. 
A)  antibodies. 
B)  immunoglobins. 
C)  T cell receptors. 
D)  None of these are correct.

Question 5

All TLR can react with only one specific PAMP.

Accepted Answer

A) True 
 B)False

Question 6

Which of the following are molecular mediators of inflammation?

Accepted Answer

A)  immunoglobulins 
B)  lipopolysaccharide 
C)  erythrocytes 
D)  both chemokines and cytokines 
A)  immunoglobulins 
B)  lipopolysaccharide 
C)  erythrocytes 
D)  both chemokines and cytokines

Question 7

Intracellular pathogens sometimes produce ________ that can kill phagocytes.

Accepted Answer

A)  lipopolysaccharides 
B)  PAMPs 
C)  PRRs 
D)  leukocidins 
A)  lipopolysaccharides 
B)  PAMPs 
C)  PRRs 
D)  leukocidins

Question 8

When dendritic cells ingest antigen, they migrate to the ________, where they present the antigen to T lymphocytes.

Accepted Answer

A)  kidneys 
B)  lymph nodes 
C)  thymus 
D)  spleen 
A)  kidneys 
B)  lymph nodes 
C)  thymus 
D)  spleen

Question 9

Briefly describe the effect of deposition of antibody or complement on the surface of a pathogen or antigen in relation to opsonization.

Accepted Answer

Opsonization is the enhancement of phago

Question 10

Immunoglobulins are produced by B cells and are also known as

Accepted Answer

A)  antibodies. 
B)  antigens. 
C)  bacteria. 
D)  pathogens. 
A)  antibodies. 
B)  antigens. 
C)  bacteria. 
D)  pathogens.

Question 11

Some Mycobacterium species produce carotenoids that neutralize singlet oxygen and prevent killing.

Accepted Answer

A) True 
 B)False

Question 12

Inflammation is the usual outcome of an adaptive immune response but not an innate immune response.

Accepted Answer

A) True 
 B)False

Question 13

Stem cells are produced and developed in the

Accepted Answer

A)  bone marrow. 
B)  brain. 
C)  liver. 
D)  stems of plants. 
A)  bone marrow. 
B)  brain. 
C)  liver. 
D)  stems of plants.

Question 14

The inflammatory cytokines IL-1, IL-6, and TNF-α are also

Accepted Answer

A)  opsonizing agents that coat foreign cells. 
B)  responsible for decreasing vascular permeability. 
C)  capable of producing systemic fever by stimulating the release of prostaglandins in the brain. 
D)  part of the classical pathway of complement activation. 
A)  opsonizing agents that coat foreign cells. 
B)  responsible for decreasing vascular permeability. 
C)  capable of producing systemic fever by stimulating the release of prostaglandins in the brain. 
D)  part of the classical pathway of complement activation.

Question 15

Which of the following is a function of dendritic cells?

Accepted Answer

A)  antigen presentation 
B)  plaque formation 
C)  phagocytosis 
D)  both phagocytosis and plaque formation 
A)  antigen presentation 
B)  plaque formation 
C)  phagocytosis 
D)  both phagocytosis and plaque formation

Question 16

Communication between cells of the immune system is accomplished in many cases through

Accepted Answer

A)  allelic exclusion. 
B)  clonal deletion. 
C)  cytokines. 
D)  allelic exclusion, clonal deletion, and cytokines. 
A)  allelic exclusion. 
B)  clonal deletion. 
C)  cytokines. 
D)  allelic exclusion, clonal deletion, and cytokines.

Question 17

Oxygen compounds toxic to pathogens include

Accepted Answer

A)  hydrogen peroxide. 
B)  hypochlorus acid. 
C)  nitric oxide. 
D)  hydrogen peroxide, hypochlorus acid, and nitric oxide. 
A)  hydrogen peroxide. 
B)  hypochlorus acid. 
C)  nitric oxide. 
D)  hydrogen peroxide, hypochlorus acid, and nitric oxide.

Question 18

Interaction of a PAMP with a TLR triggers transmembrane signal transduction and subsequent

Accepted Answer

A)  clonal expansion. 
B)  antibody production. 
C)  complement protein activation. 
D)  phagocytosis and inflammation. 
A)  clonal expansion. 
B)  antibody production. 
C)  complement protein activation. 
D)  phagocytosis and inflammation.

Question 19

How does the body respond when it first encounters a foreign particle or bacterial pathogen?

Accepted Answer

The body has defensive cells called phag

Question 20

Enhanced phagocytosis of antibody-sensitized cells is known as

Accepted Answer

A)  complementation. 
B)  immunization. 
C)  opsonization. 
D)  tolerance. 
A)  complementation. 
B)  immunization. 
C)  opsonization. 
D)  tolerance.

Exam 26: Innate Immunity: Broadly Specific Host Defenses

Which of the following can cause allergy symptoms and inflammation by degranulation?

Mannose on mammalian cells is inaccessible to mannose-binding lectin.

Antibodies are soluble proteins produced by T cells.

The unique antigen-reactive proteins of T cells are

All TLR can react with only one specific PAMP.

Which of the following are molecular mediators of inflammation?

Intracellular pathogens sometimes produce ________ that can kill phagocytes.

When dendritic cells ingest antigen, they migrate to the ________, where they present the antigen to T lymphocytes.

Briefly describe the effect of deposition of antibody or complement on the surface of a pathogen or antigen in relation to opsonization.

Immunoglobulins are produced by B cells and are also known as

Some Mycobacterium species produce carotenoids that neutralize singlet oxygen and prevent killing.

Inflammation is the usual outcome of an adaptive immune response but not an innate immune response.

Stem cells are produced and developed in the

The inflammatory cytokines IL-1, IL-6, and TNF-α are also

Which of the following is a function of dendritic cells?

Communication between cells of the immune system is accomplished in many cases through

Oxygen compounds toxic to pathogens include

Interaction of a PAMP with a TLR triggers transmembrane signal transduction and subsequent

How does the body respond when it first encounters a foreign particle or bacterial pathogen?

Enhanced phagocytosis of antibody-sensitized cells is known as

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