Exam 10: Memory Formation: Early Stages

When glutamate and ampakines both bind to the AMPA receptor, the channel stays open longer.

GluN1-GluN2A receptor complexes influx more calcium than GluN1-GluN2B receptor complexes.

Which statement(s) about NMDA receptors is/are true? (Select all that apply.)

GluN1-GluN2B to GLuN1-GLuN2A receptors ratio increases during development.

The formation of a memory trace begins when a behavioral experience activates a neuronal ensemble that represents the experience.

GluA1 KO mice _______. (Select all that apply.)

The Doogie mouse is genetically engineered to overexpress _______ subunits.

The Doogie mouse was engineered to overexpress GluN2A receptors.

How did Tonegawa's laboratory discover a role for the GluN1 receptor?

In the radial arm maze methodology, if a rat revisits an arm, it is making an error of _______ memory.

Tonegawa deleted the _______ subunit in _______ cells in the CA1 field of the mouse hippocampus.

Working memory cannot be studied in animals because they cannot communicate what problems they are trying to solve.

Describe the composition of the NMDA receptor.

The formation of a _______ begins when a behavioral experience activates a set of weakly connected neurons.

The Doogie mouse was engineered to overexpress GluN2B receptors.

Morris used a pharmacological treatment to study the role of NMDA receptors in memory formation.

What are ampakines?

In the radial arm maze methodology, if a rat revisits an arm that was never baited, it is making an error of _______ memory.

Is it reasonable to expect that behavioral experiences that produce memories would engage the LIMK signaling pathway? Why?

NMDA receptors are required for both the acquisition and the retrieval of memories.