Question 1

Which statement about mild cognitive impairment (MCI) is false?

Accepted Answer

A)  Consuming more than 2,100 calories a day increases the risk of MCI for people over age 70. 
B)  MCI invariably leads to Alzheimer's disease. 
C)  People with MCI have trouble performing more than one task at a time. 
D)  With MCI, difficult tasks take longer and longer to perform. 
A)  Consuming more than 2,100 calories a day increases the risk of MCI for people over age 70. 
B)  MCI invariably leads to Alzheimer's disease. 
C)  People with MCI have trouble performing more than one task at a time. 
D)  With MCI, difficult tasks take longer and longer to perform. B

Question 2

Multiple drugs that act as _______ are currently in use for the treatment of AD.

Accepted Answer

A)  NMDA receptor agonists 
B)  NMDA receptor antagonists 
C)  cholinesterase inhibitors 
D)  acetylcholine receptor agonists 
A)  NMDA receptor agonists 
B)  NMDA receptor antagonists 
C)  cholinesterase inhibitors 
D)  acetylcholine receptor agonists C

Question 3

Which statement about the "MitoPark" mouse model is false?

Accepted Answer

A)  Substantia nigra cells die because of deficiencies in cellular respiration. 
B)  Mice exhibit behavioral outcomes that resemble PD. 
C)  MPP+ is transported into substantia nigra cells via the transporter. 
D)  Treatment with l-DOPA reversed the observed behavioral changes. 
A)  Substantia nigra cells die because of deficiencies in cellular respiration. 
B)  Mice exhibit behavioral outcomes that resemble PD. 
C)  MPP+ is transported into substantia nigra cells via the transporter. 
D)  Treatment with l-DOPA reversed the observed behavioral changes. A

Question 4

Pharmacological treatments for Parkinson's disease include all of the following except drugs that

Accepted Answer

A)  prevent motor complications. 
B)  prevent clinical progression of the disease. 
C)  prevent the initial stages of neuronal degeneration. 
D)  treat a particular symptom. 
A)  prevent motor complications. 
B)  prevent clinical progression of the disease. 
C)  prevent the initial stages of neuronal degeneration. 
D)  treat a particular symptom.

Question 5

Two very different approaches that are currently being used to treat ALS are _______ and _______.

Accepted Answer

A)  DA agonists; GLU agonists 
B)  GLU antagonists; free radical scavengers 
C)  GLU agonists; free radical scavengers increasing neurotransmission in motor control centers of the brain 
D)  DA antagonists; stem cell therapies to produce new motor neurons 
A)  DA agonists; GLU agonists 
B)  GLU antagonists; free radical scavengers 
C)  GLU agonists; free radical scavengers increasing neurotransmission in motor control centers of the brain 
D)  DA antagonists; stem cell therapies to produce new motor neurons

Question 6

Which statement about the diagnosis of Alzheimer's disease is false?

Accepted Answer

A)  It is a diagnosis of elimination. 
B)  Amyvid can be used in conjunction with PET scans to tag beta-amyloid and confirm AD. 
C)  Amyloid plaques can occur in individuals without AD. 
D)  Other causes of dementia including stroke, vitamin deficiency, and chronic infection are ruled out before a diagnosis is made. 
A)  It is a diagnosis of elimination. 
B)  Amyvid can be used in conjunction with PET scans to tag beta-amyloid and confirm AD. 
C)  Amyloid plaques can occur in individuals without AD. 
D)  Other causes of dementia including stroke, vitamin deficiency, and chronic infection are ruled out before a diagnosis is made.

Question 7

Which statement about ALS is false?

Accepted Answer

A)  Death is caused by respiratory failure as motor neurons controlling this process are lost. 
B)  Protein aggregates known as spheroids are present in degenerating neurons. 
C)  Abnormal eye movements may serve as a marker for the disease prior to other symptoms. 
D)  Both hereditary and nonhereditary cases have been seen but genes have not been identified. 
A)  Death is caused by respiratory failure as motor neurons controlling this process are lost. 
B)  Protein aggregates known as spheroids are present in degenerating neurons. 
C)  Abnormal eye movements may serve as a marker for the disease prior to other symptoms. 
D)  Both hereditary and nonhereditary cases have been seen but genes have not been identified.

Question 8

An increase in the levels of Bacteroidetes and reductions in two other bacteria (Firmicutes and Actinobacteria) have been implicated in

Accepted Answer

A)  Parkinson's disease. 
B)  Huntington's disease. 
C)  Alzheimer's disease. 
D)  ALS. 
A)  Parkinson's disease. 
B)  Huntington's disease. 
C)  Alzheimer's disease. 
D)  ALS.

Question 9

Antipsychotic drugs are sometimes used for treating which symptom(s) in individuals with Parkinson's disease?

Accepted Answer

A)  Resting tremor 
B)  Difficulty initiating movement 
C)  Hallucinations or delusions caused by DA agonists 
D)  Depression 
A)  Resting tremor 
B)  Difficulty initiating movement 
C)  Hallucinations or delusions caused by DA agonists 
D)  Depression

Question 10

Which statement about apolipoprotein E is true?

Accepted Answer

A)  Its receptor may be increased in the brains of AD patients. 
B)  The ApoE gene is a risk gene with only a minor influence on disease development. 
C)  ApoE is normally involved in moving excess cholesterol from the blood to the liver. 
D)  Early onset AD is not linked to the E4 form of the gene. 
A)  Its receptor may be increased in the brains of AD patients. 
B)  The ApoE gene is a risk gene with only a minor influence on disease development. 
C)  ApoE is normally involved in moving excess cholesterol from the blood to the liver. 
D)  Early onset AD is not linked to the E4 form of the gene.

Question 11

Explain why the nature of the disorder accounts for the fact that patients with ALS display primarily motor problems.

Accepted Answer

ALS is considered primarily a

Question 12

Which of the following is not considered a potential risk factor of MS?

Accepted Answer

A)  In utero exposure to the influenza virus 
B)  Living in an extremely cold climate before age 15 
C)  Having a first-degree relative with MS 
D)  Previous incidence of infectious disease, including mononucleosis 
A)  In utero exposure to the influenza virus 
B)  Living in an extremely cold climate before age 15 
C)  Having a first-degree relative with MS 
D)  Previous incidence of infectious disease, including mononucleosis

Which statement about mild cognitive impairment (MCI) is false?

Multiple drugs that act as _______ are currently in use for the treatment of AD.

Which statement about the "MitoPark" mouse model is false?

Pharmacological treatments for Parkinson's disease include all of the following except drugs that

Two very different approaches that are currently being used to treat ALS are _ and _.

Which statement about the diagnosis of Alzheimer's disease is false?

Which statement about ALS is false?

An increase in the levels of Bacteroidetes and reductions in two other bacteria (Firmicutes and Actinobacteria) have been implicated in

Antipsychotic drugs are sometimes used for treating which symptom(s) in individuals with Parkinson's disease?

Which statement about apolipoprotein E is true?

Explain why the nature of the disorder accounts for the fact that patients with ALS display primarily motor problems.

Which of the following is not considered a potential risk factor of MS?

Principles of Pharmacology, Structure and Function of the Nervous System

Chemical Signaling by Neurotransmitters and Hormones

Methods of Research in Psychopharmacology

Catecholamines

Serotonin

Acetylcholine

Glutamate and GABA

Drug Abuse and Addiction

Alcohol

The Opioids

Psychomotor Stimulants:

Nicotine and Caffeine

Marijuana and the Cannabinoids

Hallucinogens, PCP, and Ketamine

Inhalants, GHB, and Anabolicandrogenic Steroids

Disorders of Anxiety and Impulsivity and the Drugs Used to Treat These Disorders

Affective Disorders: Antidepressants and Mood Stabilizers

Schizophrenia: Antipsychotic Drugs

Filters

Exam 19: Neurodegenerative Disorders

Which statement about mild cognitive impairment (MCI) is false?

Multiple drugs that act as _______ are currently in use for the treatment of AD.

Which statement about the "MitoPark" mouse model is false?

Pharmacological treatments for Parkinson's disease include all of the following except drugs that

Two very different approaches that are currently being used to treat ALS are _______ and _______.

Which statement about the diagnosis of Alzheimer's disease is false?

Which statement about ALS is false?

An increase in the levels of Bacteroidetes and reductions in two other bacteria (Firmicutes and Actinobacteria) have been implicated in

Antipsychotic drugs are sometimes used for treating which symptom(s) in individuals with Parkinson's disease?

Which statement about apolipoprotein E is true?

Explain why the nature of the disorder accounts for the fact that patients with ALS display primarily motor problems.

Which of the following is not considered a potential risk factor of MS?

Principles of Pharmacology, Structure and Function of the Nervous System

Chemical Signaling by Neurotransmitters and Hormones

Methods of Research in Psychopharmacology

Catecholamines

Serotonin

Acetylcholine

Glutamate and GABA

Drug Abuse and Addiction

Alcohol

The Opioids

Psychomotor Stimulants:

Nicotine and Caffeine

Marijuana and the Cannabinoids

Hallucinogens, PCP, and Ketamine

Inhalants, GHB, and Anabolicandrogenic Steroids

Disorders of Anxiety and Impulsivity and the Drugs Used to Treat These Disorders

Affective Disorders: Antidepressants and Mood Stabilizers

Schizophrenia: Antipsychotic Drugs

Filters

Two very different approaches that are currently being used to treat ALS are _ and _.