Question 1

Match the phases of drug testing with the appropriate description.
-Phase I

Accepted Answer

A) This phase lasts about 2 years.The number of volunteers is 100 to 300 persons with the disease to assess the effectiveness of a drug and to observe for adverse side reactions. 
B) This phase lasts about 1 year and includes 20 to 80 healthy volunteers who are tested for the safety of new drug. 
C) This phase lasts about 3 years.The number of patients with a specific disease is 1000 to 3000 to further verify effectiveness and identify any specific negative side effects of the drug. 
A) This phase lasts about 2 years.The number of volunteers is 100 to 300 persons with the disease to assess the effectiveness of a drug and to observe for adverse side reactions. 
B) This phase lasts about 1 year and includes 20 to 80 healthy volunteers who are tested for the safety of new drug. 
C) This phase lasts about 3 years.The number of patients with a specific disease is 1000 to 3000 to further verify effectiveness and identify any specific negative side effects of the drug.

Question 2

Which of the following statements is (are)true about retroviruses?

Accepted Answer

A)  They contain a single,positive-stranded ribonucleic acid (RN
A) . 
B)  They contain a special enzyme called reverse transcriptase in their core. 
C)  They reverse the normal process of transcription in which DNA is converted to RNA. 
D)  All of the above. 
A)  They contain a single,positive-stranded ribonucleic acid (RN
A) . 
B)  They contain a special enzyme called reverse transcriptase in their core. 
C)  They reverse the normal process of transcription in which DNA is converted to RNA. 
D)  All of the above.

Question 3

In HIV infections,a window period of seronegativity extends from the time of initial infection up to:

Accepted Answer

A)  2 weeks. 
B)  2 to 6 weeks or longer. 
C)  6 to 12 weeks or longer. 
D)  4 to 8 months or longer. 
A)  2 weeks. 
B)  2 to 6 weeks or longer. 
C)  6 to 12 weeks or longer. 
D)  4 to 8 months or longer.

Question 4

Match the phases of drug testing with the appropriate description.
-Phase III

Accepted Answer

A) This phase lasts about 2 years.The number of volunteers is 100 to 300 persons with the disease to assess the effectiveness of a drug and to observe for adverse side reactions. 
B) This phase lasts about 1 year and includes 20 to 80 healthy volunteers who are tested for the safety of new drug. 
C) This phase lasts about 3 years.The number of patients with a specific disease is 1000 to 3000 to further verify effectiveness and identify any specific negative side effects of the drug. 
A) This phase lasts about 2 years.The number of volunteers is 100 to 300 persons with the disease to assess the effectiveness of a drug and to observe for adverse side reactions. 
B) This phase lasts about 1 year and includes 20 to 80 healthy volunteers who are tested for the safety of new drug. 
C) This phase lasts about 3 years.The number of patients with a specific disease is 1000 to 3000 to further verify effectiveness and identify any specific negative side effects of the drug.

Question 5

Human immunodeficiency virus can enter the body with cells associated with HIV.

Accepted Answer

A) True 
 B)False

Question 6

MATCHING
Match the characteristics to the three infectious patterns of HIV.

-Pattern 2: Africa,Caribbean,parts of South America.

Accepted Answer

A) Primarily a disease of heterosexuals 
B) Fewer known cases of HIV-AIDS 
C) Primarily a disease of homosexuals and intravenous (IV)drug abusers 
A) Primarily a disease of heterosexuals 
B) Fewer known cases of HIV-AIDS 
C) Primarily a disease of homosexuals and intravenous (IV)drug abusers

Question 7

In addition to lymphocytes,___________ and skin cells can be infected by HIV.

Accepted Answer

A) macrophages 
B) monocytes 
C) cells in the lymph nodes 
D) all of the above 
A) macrophages 
B) monocytes 
C) cells in the lymph nodes 
D) all of the above

Question 8

Which gene is responsible for the coding of reverse transcriptase in the human immunodeficiency virus (HIV)?

Accepted Answer

A)  env 
B)  gag 
C)  pol 
D)  tat 
A)  env 
B)  gag 
C)  pol 
D)  tat

Exam 25: Acquired Immunodeficiency Syndrome

Match the phases of drug testing with the appropriate description. -Phase I

Which of the following statements is (are)true about retroviruses?

In HIV infections,a window period of seronegativity extends from the time of initial infection up to:

Match the phases of drug testing with the appropriate description. -Phase III

Human immunodeficiency virus can enter the body with cells associated with HIV.

MATCHING Match the characteristics to the three infectious patterns of HIV. -Pattern 2: Africa,Caribbean,parts of South America.

In addition to lymphocytes,___________ and skin cells can be infected by HIV.

Which gene is responsible for the coding of reverse transcriptase in the human immunodeficiency virus (HIV)?

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Point-Of-Care Testing

Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Automated Procedures

Molecular Techniques

The Immune Response in Infectious Diseases

A Primer on Vaccines

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Hypersensitivity Reactions

Immunoproliferative Disorders

Autoimmune Disorders

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Solid Organ Transplantation

Bone Marrow Transplantation

Tumor Immunology

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