Question 1

What is the M component in a monoclonal gammopathy?

Accepted Answer

A)  Excessive IgM antibody 
B)  Monoclonal antibody or cell line 
C)  Excessive number of macrophages 
D)  Proliferation of malignant cells 
A)  Excessive IgM antibody 
B)  Monoclonal antibody or cell line 
C)  Excessive number of macrophages 
D)  Proliferation of malignant cells

Question 2

Multiple myeloma is the most common form of dysproteinemia.It accounts for (1)_______% of all types of malignant diseases and (2)_______% of hematologic malignancies.
A)1
B)10
C)15
D)25

Accepted Answer

1,A;2,B
Multiple myeloma (MM),the most c

Question 3

Match the types of cryoglobulin with the correct description.

-Type III

Accepted Answer

A) Mixed cryoglobulins in which both constituent immunoglobulins are polyclonal.More than 90% contain IgM rheumatoid factor and IgG.These cryoglobulins are seen in a variety of autoimmune,systemic rheumatic diseases and persistent infections with immune complexes (e.g. ,bacterial endocarditis). 
B) Cryoglobulins composed of a single class;IgM and IgG classes most common;IgA or light-chain,single cryoglobulins seen less frequently.This type constitutes about 25% of cryoglobulins and is generally associated with multiple myeloma,macroglobulinemia,and other,rarer neoplastic proliferations of plasma cells and lymphocytes. 
C) Cryoglobulins consist of two forms.The monoclonal form always has rheumatoid factor activity and usually is an IgM with k light chains.The second form is polyclonal IgG,which reacts with the monoclonal IgM rheumatoid factor. 
A) Mixed cryoglobulins in which both constituent immunoglobulins are polyclonal.More than 90% contain IgM rheumatoid factor and IgG.These cryoglobulins are seen in a variety of autoimmune,systemic rheumatic diseases and persistent infections with immune complexes (e.g. ,bacterial endocarditis). 
B) Cryoglobulins composed of a single class;IgM and IgG classes most common;IgA or light-chain,single cryoglobulins seen less frequently.This type constitutes about 25% of cryoglobulins and is generally associated with multiple myeloma,macroglobulinemia,and other,rarer neoplastic proliferations of plasma cells and lymphocytes. 
C) Cryoglobulins consist of two forms.The monoclonal form always has rheumatoid factor activity and usually is an IgM with k light chains.The second form is polyclonal IgG,which reacts with the monoclonal IgM rheumatoid factor.

Question 4

Bence Jones proteinuria is often associated with:

Accepted Answer

A)  intrarenal obstruction. 
B)  direct tubular-cell injury. 
C)  renal failure. 
D)  all of the above. 
A)  intrarenal obstruction. 
B)  direct tubular-cell injury. 
C)  renal failure. 
D)  all of the above.

Question 5

MATCHING
Match the terms with the appropriate definition.

-Monoclonal gammopathy

Accepted Answer

A) Benign or malignant condition that results from a single clone of lymphoid-plasma cells producing elevated levels of a single class and type of immunoglobulin 
B) Condition characterized by the elevation of two or more immunoglobulins by several clones of plasma cells 
A) Benign or malignant condition that results from a single clone of lymphoid-plasma cells producing elevated levels of a single class and type of immunoglobulin 
B) Condition characterized by the elevation of two or more immunoglobulins by several clones of plasma cells

What is the M component in a monoclonal gammopathy?

Multiple myeloma is the most common form of dysproteinemia.It accounts for (1)_% of all types of malignant diseases and (2)_% of hematologic malignancies. A)1 B)10 C)15 D)25

Match the types of cryoglobulin with the correct description. -Type III

Bence Jones proteinuria is often associated with:

MATCHING Match the terms with the appropriate definition. -Monoclonal gammopathy

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Point-Of-Care Testing

Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Automated Procedures

Molecular Techniques

The Immune Response in Infectious Diseases

A Primer on Vaccines

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Acquired Immunodeficiency Syndrome

Hypersensitivity Reactions

Autoimmune Disorders

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Solid Organ Transplantation

Bone Marrow Transplantation

Tumor Immunology

Filters

Exam 27: Immunoproliferative Disorders

What is the M component in a monoclonal gammopathy?

Multiple myeloma is the most common form of dysproteinemia.It accounts for (1)_______% of all types of malignant diseases and (2)_______% of hematologic malignancies. A)1 B)10 C)15 D)25

Match the types of cryoglobulin with the correct description. -Type III

Bence Jones proteinuria is often associated with:

MATCHING Match the terms with the appropriate definition. -Monoclonal gammopathy

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Point-Of-Care Testing

Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Automated Procedures

Molecular Techniques

The Immune Response in Infectious Diseases

A Primer on Vaccines

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Acquired Immunodeficiency Syndrome

Hypersensitivity Reactions

Autoimmune Disorders

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Solid Organ Transplantation

Bone Marrow Transplantation

Tumor Immunology

Filters

Multiple myeloma is the most common form of dysproteinemia.It accounts for (1)_% of all types of malignant diseases and (2)_% of hematologic malignancies. A)1 B)10 C)15 D)25