Question 1

Which of the following represents a palindromic sequence?

Accepted Answer

A) ACCTTCCA 
B) ATTCCAAT 
C) GATTAATC 
D) GGTAATCC 
E) none of the above 
A) ACCTTCCA 
B) ATTCCAAT 
C) GATTAATC 
D) GGTAATCC 
E) none of the above

Question 2

Draw the two forms of a phosphodiester bond that can occur under physiological pH. If the pKa for this conversion is 6.2, what form predominates in the lysosome where the pH is about 5?

Accepted Answer

@#IMG-DLM& The protonated form

Question 3

Which of the following is the most commonly observed nucleic acid form for storing of genomic information?

Accepted Answer

A) single-stranded DNA 
B) double-stranded DNA 
C) single-stranded RNA 
D) double-stranded RNA 
E) hybrid molecules of DNA and RNA 
A) single-stranded DNA 
B) double-stranded DNA 
C) single-stranded RNA 
D) double-stranded RNA 
E) hybrid molecules of DNA and RNA

Question 4

Which of the following base pairs would have 2 hydrogen bonds and a distance between C-1' of 1.08 nm?

Accepted Answer

A) A-C 
B) G-C 
C) A-T 
D) G-T 
E) none of the above 
A) A-C 
B) G-C 
C) A-T 
D) G-T 
E) none of the above

Question 5

From the following polynucleotide sequence, one would conclude which of the following? ACCAGTCG

Accepted Answer

A) the base found at the 3' end of the molecule is adenine 
B) the base found at the 5' end of the molecule is adenine 
C) the terminal adenosine contains a free 3' hydroxyl group 
D) the terminal guanosine contains a free 5' phosphate group 
E) none of the above 
A) the base found at the 3' end of the molecule is adenine 
B) the base found at the 5' end of the molecule is adenine 
C) the terminal adenosine contains a free 3' hydroxyl group 
D) the terminal guanosine contains a free 5' phosphate group 
E) none of the above

Question 6

Show the typical hydrogen bonds that from when adenine pairs with its complimentary base.

Accepted Answer

The answer of Show the typical hydrogen bonds that from...

Question 7

Which of the following correctly describes the structure of a nucleotide?

Accepted Answer

A) adenine is bound via a link between N-7 and C-1 of ribose 
B) phosphates are always bound to C-2 of ribose 
C) cytosine is bound via a link between the amine on C-4 and C-1 of ribose 
D) guanine is bound via a link between N-9 and C-1 of ribose 
E) none of the above 
A) adenine is bound via a link between N-7 and C-1 of ribose 
B) phosphates are always bound to C-2 of ribose 
C) cytosine is bound via a link between the amine on C-4 and C-1 of ribose 
D) guanine is bound via a link between N-9 and C-1 of ribose 
E) none of the above

Question 8

Which of the following secondary structures is correctly identified?

Accepted Answer

A) Z-DNA: left-handed DNA with pyrimidines in the syn conformation and purines in the anti conformation 
B) hairpin structure: self-complimentary single stranded molecules that form a parallel helix 
C) cruciform: a double hairpin formed in a region of palindromic DNA 
D) H-DNA: triple helical structure that results when Watson-Crick base pairing does not form and instead, Hoogsteen base pairing occurs 
E) none of the above 
A) Z-DNA: left-handed DNA with pyrimidines in the syn conformation and purines in the anti conformation 
B) hairpin structure: self-complimentary single stranded molecules that form a parallel helix 
C) cruciform: a double hairpin formed in a region of palindromic DNA 
D) H-DNA: triple helical structure that results when Watson-Crick base pairing does not form and instead, Hoogsteen base pairing occurs 
E) none of the above

Which of the following represents a palindromic sequence?

Draw the two forms of a phosphodiester bond that can occur under physiological pH. If the pK_a for this conversion is 6.2, what form predominates in the lysosome where the pH is about 5?

Which of the following is the most commonly observed nucleic acid form for storing of genomic information?

Which of the following base pairs would have 2 hydrogen bonds and a distance between C-1' of 1.08 nm?

From the following polynucleotide sequence, one would conclude which of the following? ACCAGTCG

Show the typical hydrogen bonds that from when adenine pairs with its complimentary base.

Which of the following correctly describes the structure of a nucleotide?

Which of the following secondary structures is correctly identified?

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars, Saccharides, Glycans

Lipids, Membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Lipid Metabolism Ii: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, Utilization, and Turnover

Metabolism of Nitogenous Compounds II: Amino Acids, Porphyrins, and Neurotransmitters

Nucleotide Metabolism

Mechanisms of Signal Transduction

Genes, Genomes and Chromosomes

DNA Replication

DNA Restructuring: Repair, Recombination, Rearrangement, Amplification

Information Readout: Transcription and Post-Transcriptional Processing

Information Decoding: Translation and Post-Translational Protein Processing

Regulation of Gene Expression

Filters

Exam 4: Nucleic Acids

Which of the following represents a palindromic sequence?

Draw the two forms of a phosphodiester bond that can occur under physiological pH. If the pKa for this conversion is 6.2, what form predominates in the lysosome where the pH is about 5?

Which of the following is the most commonly observed nucleic acid form for storing of genomic information?

Which of the following base pairs would have 2 hydrogen bonds and a distance between C-1' of 1.08 nm?

From the following polynucleotide sequence, one would conclude which of the following? ACCAGTCG

Show the typical hydrogen bonds that from when adenine pairs with its complimentary base.

Which of the following correctly describes the structure of a nucleotide?

Which of the following secondary structures is correctly identified?

The Scope of Biochemistry

The Matrix of Life: Weak Interactions in an Aqueous Environment

The Energetics of Life

Introduction to Proteins: the Primary Level of Protein Structure

The Three-Dimensional Structure of Proteins

Protein Function and Evolution

Contractile Proteins and Molecular Motors

Carbohydrates: Sugars, Saccharides, Glycans

Lipids, Membranes and Cellular Transport

Enzymes: Biological Catalysts

Chemical Logic of Metabolism

Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway

Citric Acid Cycle and Glyoxylate Cycle

Electron Transport, Oxidative Phosphorylation, and Oxygen Metabolism

Photosynthesis

Lipid Metabolism I: Fatty Acids, Triacylglycerols, and Lipoproteins

Interorgan and Intracellular Coordination of Energy Metabolism in Vertebrates

Lipid Metabolism Ii: Membrane Lipids, Steroids, Isoprenoids, and Eicosanoids

Metabolism of Nitrogenous Compounds I: Principles of Biosynthesis, Utilization, and Turnover

Metabolism of Nitogenous Compounds II: Amino Acids, Porphyrins, and Neurotransmitters

Nucleotide Metabolism

Mechanisms of Signal Transduction

Genes, Genomes and Chromosomes

DNA Replication

DNA Restructuring: Repair, Recombination, Rearrangement, Amplification

Information Readout: Transcription and Post-Transcriptional Processing

Information Decoding: Translation and Post-Translational Protein Processing

Regulation of Gene Expression

Filters

Draw the two forms of a phosphodiester bond that can occur under physiological pH. If the pK_a for this conversion is 6.2, what form predominates in the lysosome where the pH is about 5?